ID   B3RB98_CUPTR            Unreviewed;       481 AA.
AC   B3RB98;
DT   02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   02-SEP-2008, sequence version 1.
DT   27-MAR-2024, entry version 87.
DE   SubName: Full=NAD+-dependent betaine aldehyde dehydrogenase {ECO:0000313|EMBL:CAQ72173.1};
DE            EC=1.2.1.8 {ECO:0000313|EMBL:CAQ72173.1};
GN   Name=betB2 {ECO:0000313|EMBL:CAQ72173.1};
GN   OrderedLocusNames=RALTA_B1578 {ECO:0000313|EMBL:CAQ72173.1};
OS   Cupriavidus taiwanensis (strain DSM 17343 / BCRC 17206 / CCUG 44338 / CIP
OS   107171 / LMG 19424 / R1) (Ralstonia taiwanensis (strain LMG 19424)).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=977880 {ECO:0000313|EMBL:CAQ72173.1, ECO:0000313|Proteomes:UP000001692};
RN   [1] {ECO:0000313|EMBL:CAQ72173.1, ECO:0000313|Proteomes:UP000001692}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17343 / BCRC 17206 / CCUG 44338 / CIP 107171 / LMG 19424 /
RC   R1 {ECO:0000313|Proteomes:UP000001692};
RX   PubMed=18490699; DOI=10.1101/gr.076448.108;
RA   Amadou C., Pascal G., Mangenot S., Glew M., Bontemps C., Capela D.,
RA   Carrere S., Cruveiller S., Dossat C., Lajus A., Marchetti M., Poinsot V.,
RA   Rouy Z., Servin B., Saad M., Schenowitz C., Barbe V., Batut J., Medigue C.,
RA   Masson-Boivin C.;
RT   "Genome sequence of the beta-rhizobium Cupriavidus taiwanensis and
RT   comparative genomics of rhizobia.";
RL   Genome Res. 18:1472-1483(2008).
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC       {ECO:0000256|RuleBase:RU003345}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CU633750; CAQ72173.1; -; Genomic_DNA.
DR   RefSeq; WP_012356389.1; NC_010530.1.
DR   AlphaFoldDB; B3RB98; -.
DR   GeneID; 29764370; -.
DR   KEGG; cti:RALTA_B1578; -.
DR   eggNOG; COG1012; Bacteria.
DR   HOGENOM; CLU_005391_1_0_4; -.
DR   BioCyc; CTAI977880:RALTA_RS23235-MONOMER; -.
DR   Proteomes; UP000001692; Chromosome 2.
DR   GO; GO:0008802; F:betaine-aldehyde dehydrogenase activity; IEA:UniProtKB-EC.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR016160; Ald_DH_CS_CYS.
DR   InterPro; IPR029510; Ald_DH_CS_GLU.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR   PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU003345}.
FT   DOMAIN          12..477
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   COILED          67..94
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   ACT_SITE        248
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ   SEQUENCE   481 AA;  50963 MW;  60152B63481B5E2F CRC64;
     MTVFLNHIDG EWTACQSGRT FDNINPADTA DLVGRFQASS AVDAHAAVAA AAAAFAGWKK
     TPVGKRAAIL NRAAEHLEAN ADSIAAELTR EEGKALALAR DEVLRSAQTL RFYAVEGQTF
     TGEVFPNDDP DQLVYSQREP LGVVTVIAPW NFPVSIPARK IAPALVTGNT VVFKPSSEAP
     LSGYRLAEAL VKAGLPKGVL NFITGSAAEI GAAITEAPAV RAISFTGSSR AGEQIHRAVP
     LTTRTQMELG GKNPLIVMED ADLDRAVDLT IKGGFSLSGQ ACTGTSRVLV GEAVKAAYTE
     RLLAKVATLK VGSGMAPGMD LGPLASQKQL ETVLRYIDIG RSEATLLCGG MRLTGGDFDK
     GYYVAPTVFT DVTQQMRIAR EEIFGPVIAI LGFTDYADAI AKANDTEYGL AAAIVTSNPR
     YIHHFASDIE AGTVKINRTT TGNLVNAPFG GVKRSSTSTF RESGRTGLEF YTQVKTVYRG
     A
//