B3R9B5 (B3R9B5_CUPTR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Error-prone DNA polymerase 1 HAMAP MF_01902
EC=2.7.7.7 HAMAP MF_01902

Gene names

Name:	dnaE2 EMBL CAQ71490.1
Synonyms:	dnaE2-1 HAMAP MF_01902
Ordered Locus Names:	RALTA_B0874

Organism

Cupriavidus taiwanensis (strain R1 / LMG 19424) (Ralstonia taiwanensis (strain LMG 19424)) [Complete proteome] [HAMAP]

Taxonomic identifier

164546 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Cupriavidus

Protein attributes

Sequence length	1121 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902 SAAS SAAS004013
Subcellular location	Cytoplasm By similarity HAMAP MF_01902 SAAS SAAS004013.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP MF_01902

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP MF_01902 SAAS SAAS004013 DNA replication HAMAP MF_01902 SAAS SAAS004013
Cellular component	Cytoplasm HAMAP MF_01902 SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase HAMAP MF_01902 SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B3R9B5 [UniParc]. Last modified September 2, 2008. Version 1. Checksum: 8E3F18BC897E1193	FASTA	1,121	124,321
	10 20 30 40 50 60 MPDYVELHCI SNFTFLTGAS HPGELIERAF GLGYSGLALT DECSVAGTAR AHDAIETLRK 70 80 90 100 110 120 RLHDAVERSA ARGEEGVDEP LLDDEASDAG DDDPHAHASR HQRLQALARA ADAFRLLIGS 130 140 150 160 170 180 RFSLTPADGS ERAPLRLVLI AQHREGFGNL SELITLGRRR AQKGSYRLHP EDLSEPAAGE 190 200 210 220 230 240 AHLRGMPGCV ALLLPDYCAE PERLLAQAEW CRAVFGERAW IALEQLQGHA DALHRARLEA 250 260 270 280 290 300 VSAQTGVPLA AAGAVTMHVR SRKPLSDVLT AIRLGQPLAE CGMALAPNAE QHLRMRQVLS 310 320 330 340 350 360 RLYPREALAQ TLKIAESCDF SLATLRYEYP EELVPPGETP ISYLRKEVER GKRERFPNGL 370 380 390 400 410 420 KPEWEEQLKE ELELIEEKHY EPFFLTVHDI VRFARSRGIL CQGRGSAANS LVCFCLYVTE 430 440 450 460 470 480 VSPEQANLLF GRFLSRERDE PPDIDVDFEH QRREEVIQYI YDKYGRHRAA LAASLITYRS 490 500 510 520 530 540 RSALRDVGRA LGIDASVVEQ VVKGQAWWDG GPGFVDKIAR YGLDPESPAV QQWASLTAQL 550 560 570 580 590 600 RGFPRHLSQH VGGFVIARHK LSRLVPIENA AMADRSVIQW DKDDLESLGL LKVDVLALGM 610 620 630 640 650 660 LSAIRRALEM IPNPSRDPAR AGLPARMEDI PKEDKPTYDM ICRADTIGVF QIESRAQQSM 670 680 690 700 710 720 LPRLQPREYY DLVVEVAIVR PGPIQGGMVH PYLKRREAFR RTQKPPVYFN AVIEKVLGRT 730 740 750 760 770 780 LGVPIFQEQV MQLAIDAAGF SPGQADQLRR SMAAWRRRGD LRQHQDALVR ALTGNGYPES 790 800 810 820 830 840 FALAICKQIE GFGEYGFPES HAASFAKLVY VSSWLKCHHP AAFLCALLNS QPMGFYSPSQ 850 860 870 880 890 900 LVQDARRHDV EVLPVDVTIS RWDSTLEPVA ESDAAIIRQE RPPHPRVRLG LGRVKGMREA 910 920 930 940 950 960 AALRIEAARA QRAFDSVEDL ALRAGLDRHD IDVLAAADAL APLAGNRRQA RWQARAAAAH 970 980 990 1000 1010 1020 AAHRDLLYEA PPAEAALALP APRLGEDVTA DYASLGLSLK SHPLALLRHK LAAMRFATAS 1030 1040 1050 1060 1070 1080 QLERCANGRR VRACGIVTVR QRPSTASGTI FATIEDETGS INLILWPDLV ERQRKEVLGA 1090 1100 1110 1120 TLLGVVGTWQ RQGDVRHLVA QELVDLSPML GRLLVGSRDF H

References

[1]

"Genome sequence of the beta-rhizobium Cupriavidus taiwanensis and comparative genomics of rhizobia." Amadou C., Pascal G., Mangenot S., Glew M., Bontemps C., Capela D., Carrere S., Cruveiller S., Dossat C., Lajus A., Marchetti M., Poinsot V., Rouy Z., Servin B., Saad M., Schenowitz C., Barbe V., Batut J., Medigue C., Masson-Boivin C. Genome Res. 18:1472-1483(2008) [PubMed: 18490699] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU633750 Genomic DNA. Translation: CAQ71490.1.
RefSeq	YP_002007547.1. NC_010530.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B3R9B5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6456790.
GenomeReviews	Gene locus RALTA_B0874 in contig CU633750_GR.
KEGG	cti:RALTA_B0874.
PATRIC	21535525. VBICupTai42494_4372.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG734490.
OMA	RCANGRR.
ProtClustDB	PRK05672.
Family and domain databases
HAMAP	MF_01902. DNApol_error_prone. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR023073. DNA_pol_error_prone. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR004805. PolC_alpha. [Graphical view]
KO	K14162.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B3R9B5_CUPTR

Accession

Primary (citable) accession number: B3R9B5

Entry history

Integrated into UniProtKB/TrEMBL:	September 2, 2008
Last sequence update:	September 2, 2008
Last modified:	December 14, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)