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Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene

aat

Organism
Cupriavidus taiwanensis (strain DSM 17343 / BCRC 17206 / CIP 107171 / LMG 19424 / R1) (Ralstonia taiwanensis (strain LMG 19424))
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + N-terminal L-lysyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-lysyl-[protein].UniRule annotation
L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-arginyl-[protein].UniRule annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase

Enzyme and pathway databases

BioCyciCTAI977880:G1GJV-1273-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation (EC:2.3.2.6UniRule annotation)
Alternative name(s):
L/F-transferaseUniRule annotation
LeucyltransferaseUniRule annotation
PhenyalanyltransferaseUniRule annotation
Gene namesi
Name:aatUniRule annotation
Ordered Locus Names:RALTA_A1316
OrganismiCupriavidus taiwanensis (strain DSM 17343 / BCRC 17206 / CIP 107171 / LMG 19424 / R1) (Ralstonia taiwanensis (strain LMG 19424))
Taxonomic identifieri977880 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus
Proteomesi
  • UP000001692 Componenti: Chromosome 1

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001319151 – 250Leucyl/phenylalanyl-tRNA--protein transferaseAdd BLAST250

Interactioni

Protein-protein interaction databases

STRINGi977880.RALTA_A1316

Structurei

3D structure databases

SMRiB3R4T2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108R4Z Bacteria
COG2360 LUCA
HOGENOMiHOG000102325
KOiK00684
OMAiYRQGIFP

Family and domain databases

HAMAPiMF_00688 Leu_Phe_trans, 1 hit
InterProiView protein in InterPro
IPR016181 Acyl_CoA_acyltransferase
IPR004616 Leu/Phe-tRNA_Trfase
PANTHERiPTHR30098 PTHR30098, 1 hit
PfamiView protein in Pfam
PF03588 Leu_Phe_trans, 1 hit
SUPFAMiSSF55729 SSF55729, 1 hit
TIGRFAMsiTIGR00667 aat, 1 hit

Sequencei

Sequence statusi: Complete.

B3R4T2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIAWLDPQDP FPPVEHALGP DSEAPGLLAA SRELSPQRLL LAYRQGIFPW
60 70 80 90 100
YSSGQPVLWW STDPRMVLAP PALRVSVNLR KTLRRVLRDA DWEIRVDHDF
110 120 130 140 150
LAVMRACAST PREGQDGTWI TDAIIAAYGA LHRNGLAHSV ESWYRGERVG
160 170 180 190 200
GLYGVALGRM FFGESMFAHR TDASKIALAA LCAFLGNHGV AMIDCQQETD
210 220 230 240 250
HLASLGARPI PRAEFVAHVR AATAQPAISP WRFDKSVLER WAGTPAAPAA
Length:250
Mass (Da):27,484
Last modified:September 2, 2008 - v1
Checksum:i0AF58527BAA15EAA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU633749 Genomic DNA Translation: CAQ69275.1
RefSeqiWP_012352601.1, NC_010528.1

Genome annotation databases

EnsemblBacteriaiCAQ69275; CAQ69275; RALTA_A1316
GeneIDi29760752
KEGGicti:RALTA_A1316

Similar proteinsi

Entry informationi

Entry nameiLFTR_CUPTR
AccessioniPrimary (citable) accession number: B3R4T2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 2, 2008
Last modified: April 25, 2018
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health