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B3R1Z9 (RNC_CUPTR) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribonuclease 3
EC=3.1.26.3
Alternative name(s):
Ribonuclease III
Short name=RNase III
Gene names
Name:rnc
Ordered Locus Names:RALTA_A2056
OrganismCupriavidus taiwanensis (strain R1 / LMG 19424) (Ralstonia taiwanensis (strain LMG 19424)) [Complete proteome] [HAMAP]
Taxonomic identifier164546 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Cupriavidus

Protein attributes

Sequence length256 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon By similarity. HAMAP-Rule MF_00104

Catalytic activity

Endonucleolytic cleavage to 5'-phosphomonoester. HAMAP-Rule MF_00104

Cofactor

Mg2+ By similarity.

Subunit structure

Homodimer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Contains 1 DRBM (double-stranded RNA-binding) domain.

Contains 1 RNase III domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 256256Ribonuclease 3 HAMAP-Rule MF_00104
PRO_1000094105

Regions

Domain3 – 125123RNase III
Domain152 – 22271DRBM

Sites

Active site421 Potential
Active site1141 By similarity
Metal binding381Magnesium By similarity
Metal binding1111Magnesium By similarity
Metal binding1141Magnesium By similarity

Sequences

Sequence LengthMass (Da)Tools
B3R1Z9 [UniParc].

Last modified September 2, 2008. Version 1.
Checksum: 20EB73F316AA076A

FASTA25628,519
        10         20         30         40         50         60 
MNLDALQQRL GYRFSKPELL QQALTHRSHS AQHNERLEFL GDSVLNCAVA DMLYGMFGKL 

        70         80         90        100        110        120 
DEGDLSRVRA NLVKQQALYE IAQMLQLSDT LRLGEGELKS GGFRRPSILA DALEAIVGAV 

       130        140        150        160        170        180 
FLDAGFDAAR ALIRKLYIPI LEQVDPRTLG KDAKTLLQEY LQGHKIALPQ YNVIATHGAA 

       190        200        210        220        230        240 
HSQQFEVECT VPKLEVRVFG TGASRRAAEQ AAAKLALDEV QKLVPQLLKR SRAERTGKTR 

       250 
KQPQPQDPQL SLRLKE

« Hide

References

[1]"Genome sequence of the beta-rhizobium Cupriavidus taiwanensis and comparative genomics of rhizobia."
Amadou C., Pascal G., Mangenot S., Glew M., Bontemps C., Capela D., Carrere S., Cruveiller S., Dossat C., Lajus A., Marchetti M., Poinsot V., Rouy Z., Servin B., Saad M., Schenowitz C., Barbe V., Batut J., Medigue C., Masson-Boivin C.
Genome Res. 18:1472-1483(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: R1 / LMG 19424.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CU633749 Genomic DNA. Translation: CAQ69996.1.
RefSeqYP_002006059.1. NC_010528.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRING164546.RALTA_A2056.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAQ69996; CAQ69996; RALTA_A2056.
GeneID6454429.
KEGGcti:RALTA_A2056.
PATRIC21530742. VBICupTai42494_2016.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0571.
HOGENOMHOG000246809.
KOK03685.
OMALTHKSCK.
ProtClustDBPRK00102.

Enzyme and pathway databases

BioCycCTAI164546:GJNE-2051-MONOMER.

Family and domain databases

Gene3D1.10.1520.10. 1 hit.
3.30.160.20. 1 hit.
HAMAPMF_00104. RNase_III.
InterProIPR001159. Ds-RNA-bd.
IPR014720. dsRNA-bd-like_dom.
IPR011907. RNase_III.
IPR000999. RNase_III_dom.
[Graphical view]
PANTHERPTHR11207. PTHR11207. 1 hit.
PfamPF00035. dsrm. 1 hit.
PF00636. Ribonuclease_3. 1 hit.
[Graphical view]
SMARTSM00358. DSRM. 1 hit.
SM00535. RIBOc. 1 hit.
[Graphical view]
SUPFAMSSF69065. RNase_III. 1 hit.
TIGRFAMsTIGR02191. RNaseIII. 1 hit.
PROSITEPS50137. DS_RBD. 1 hit.
PS00517. RNASE_3_1. 1 hit.
PS50142. RNASE_3_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRNC_CUPTR
AccessionPrimary (citable) accession number: B3R1Z9
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 2, 2008
Last modified: May 1, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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