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B3R075 (RNC_PHYMT) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribonuclease 3
EC=3.1.26.3
Alternative name(s):
Ribonuclease III
Short name=RNase III
Gene names
Name:rnc
Ordered Locus Names:ATP_00052
OrganismPhytoplasma mali (strain AT) [Complete proteome] [HAMAP]
Taxonomic identifier482235 [NCBI]
Taxonomic lineageBacteria › Tenericutes › Mollicutes › Acholeplasmatales › Acholeplasmataceae › Candidatus Phytoplasma › 16SrX (Apple proliferation group) ›

Protein attributes

Sequence length225 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon By similarity. HAMAP-Rule MF_00104

Catalytic activity

Endonucleolytic cleavage to 5'-phosphomonoester. HAMAP-Rule MF_00104

Cofactor

Mg2+ By similarity.

Subunit structure

Homodimer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Contains 1 DRBM (double-stranded RNA-binding) domain.

Contains 1 RNase III domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 225225Ribonuclease 3 HAMAP-Rule MF_00104
PRO_1000202841

Regions

Domain2 – 128127RNase III
Domain152 – 22069DRBM

Sites

Active site471 Potential
Active site1171 By similarity
Metal binding431Magnesium By similarity
Metal binding1141Magnesium By similarity
Metal binding1171Magnesium By similarity

Sequences

Sequence LengthMass (Da)Tools
B3R075 [UniParc].

Last modified September 2, 2008. Version 1.
Checksum: 1F90DE8305A26BE2

FASTA22525,768
        10         20         30         40         50         60 
MLSTLIKKLK IKPKQISLYK MSITHSSYAN ENKLKKKDNE RLEFLGDAVI NLLMADYLYT 

        70         80         90        100        110        120 
KKEKENEGFM SKKRAQSVCE DSLVIYAKSI QLQNYILLGK GEKNKNINNS ILANAFEALF 

       130        140        150        160        170        180 
GAIYLDLGYY IAKKVFILIV IPRLSNIIDN IDFKTQLQEL VQSQKKTISY YITEEKGLDH 

       190        200        210        220 
SKEFTAEVFL EKKNVGRGFG KTKKSAEQDA ARYVLNILSK GEKND

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References

[1]"The linear chromosome of the plant-pathogenic mycoplasma 'Candidatus Phytoplasma mali'."
Kube M., Schneider B., Kuhl H., Dandekar T., Heitmann K., Migdoll A.M., Reinhardt R., Seemueller E.
BMC Genomics 9:306-306(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AT.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CU469464 Genomic DNA. Translation: CAP18239.1.
RefSeqYP_002004094.1. NC_011047.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRING37692.ATP_00052.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAP18239; CAP18239; ATP_00052.
GeneID6450605.
KEGGpml:ATP_00052.
PATRIC31994283. VBICanPhy52977_0054.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0571.
HOGENOMHOG000246808.
KOK03685.
OMARACELPR.
ProtClustDBCLSK343805.

Family and domain databases

Gene3D1.10.1520.10. 1 hit.
3.30.160.20. 1 hit.
HAMAPMF_00104. RNase_III.
InterProIPR001159. Ds-RNA-bd.
IPR014720. dsRNA-bd-like_dom.
IPR011907. RNase_III.
IPR000999. RNase_III_dom.
[Graphical view]
PANTHERPTHR11207. PTHR11207. 1 hit.
PfamPF00035. dsrm. 1 hit.
PF00636. Ribonuclease_3. 1 hit.
[Graphical view]
SMARTSM00358. DSRM. 1 hit.
SM00535. RIBOc. 1 hit.
[Graphical view]
SUPFAMSSF69065. RNase_III. 1 hit.
TIGRFAMsTIGR02191. RNaseIII. 1 hit.
PROSITEPS50137. DS_RBD. 1 hit.
PS00517. RNASE_3_1. 1 hit.
PS50142. RNASE_3_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRNC_PHYMT
AccessionPrimary (citable) accession number: B3R075
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: September 2, 2008
Last modified: May 1, 2013
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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