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B3QZG1

- PNP_PHYMT

UniProt

B3QZG1 - PNP_PHYMT

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Protein

Polyribonucleotide nucleotidyltransferase

Gene

pnp

Organism
Phytoplasma mali (strain AT)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.UniRule annotation

Catalytic activityi

RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotation

Cofactori

Magnesium.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi513 – 5131MagnesiumUniRule annotation
Metal bindingi519 – 5191MagnesiumUniRule annotation

GO - Molecular functioni

  1. 3'-5'-exoribonuclease activity Source: InterPro
  2. magnesium ion binding Source: UniProtKB-HAMAP
  3. polyribonucleotide nucleotidyltransferase activity Source: UniProtKB-HAMAP
  4. RNA binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. mRNA catabolic process Source: UniProtKB-HAMAP
  2. RNA processing Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Ligandi

Magnesium, Metal-binding, RNA-binding

Enzyme and pathway databases

BioCyciPMAL37692:GC0T-415-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Polyribonucleotide nucleotidyltransferaseUniRule annotation (EC:2.7.7.8UniRule annotation)
Alternative name(s):
Polynucleotide phosphorylaseUniRule annotation
Short name:
PNPaseUniRule annotation
Gene namesi
Name:pnpUniRule annotation
Ordered Locus Names:ATP_00381
OrganismiPhytoplasma mali (strain AT)
Taxonomic identifieri482235 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesAcholeplasmatalesAcholeplasmataceaeCandidatus Phytoplasma16SrX (Apple proliferation group)
ProteomesiUP000002020: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 728728Polyribonucleotide nucleotidyltransferasePRO_0000381910Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi37692.ATP_00381.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini580 – 64061KHUniRule annotationAdd
BLAST
Domaini650 – 72475S1 motifUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the polyribonucleotide nucleotidyltransferase family.UniRule annotation
Contains 1 KH domain.UniRule annotation
Contains 1 S1 motif domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG1185.
HOGENOMiHOG000218326.
KOiK00962.
OMAiGTENTIC.
OrthoDBiEOG6WT8CC.

Family and domain databases

Gene3Di1.10.10.400. 1 hit.
2.40.50.140. 1 hit.
3.30.1370.10. 1 hit.
3.30.230.70. 2 hits.
HAMAPiMF_01595. PNPase.
InterProiIPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
IPR012340. NA-bd_OB-fold.
IPR012162. PNPase.
IPR027408. PNPase/RNase_PH_dom.
IPR015848. PNPase_PH_RNA-bd_bac/org-type.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR022967. S1_dom.
[Graphical view]
PANTHERiPTHR11252. PTHR11252. 1 hit.
PfamiPF00013. KH_1. 1 hit.
PF03726. PNPase. 1 hit.
PF01138. RNase_PH. 2 hits.
PF03725. RNase_PH_C. 2 hits.
PF00575. S1. 1 hit.
[Graphical view]
PIRSFiPIRSF005499. PNPase. 1 hit.
SMARTiSM00322. KH. 1 hit.
SM00316. S1. 1 hit.
[Graphical view]
SUPFAMiSSF46915. SSF46915. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF54211. SSF54211. 2 hits.
SSF54791. SSF54791. 1 hit.
SSF55666. SSF55666. 2 hits.
TIGRFAMsiTIGR03591. polynuc_phos. 1 hit.
PROSITEiPS50084. KH_TYPE_1. 1 hit.
PS50126. S1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3QZG1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDLNTKNNNK KVFEIIFENN VLRIEIGEIS RQANGSVMLF YKDTVILSVA
60 70 80 90 100
VCGDKKNSLN FLPLTVNYQE KLYAAGKIPG GFLRREGKPS DQEILCSRLI
110 120 130 140 150
DRTIRPLFSK NFKNEVQLIN MVLSSDPDGN NENIALLGSS LALLISDIPF
160 170 180 190 200
FEPVSSVCVG KIGDNLIINP TLSQRENSSF FLILAGTKDS LNMVEMSSKE
210 220 230 240 250
ISENNFLESI KFGHEIIKKL CLFQTEIANQ IGKTKIKIPL HNVNNLLEVE
260 270 280 290 300
IKDKYFSEIE MILKNKCNVN NVKKSDILKK LKENVLENYK EKFLNNKKDN
310 320 330 340 350
FNLLDLENQK LYLNEVEIIF DFLVRTIIRE TILKENIRPD GRNSSEIRSI
360 370 380 390 400
TSRIDILPRT HGSALFTRGG TQSLAIVTLG TLRESKIIDD LSDEVDKRFM
410 420 430 440 450
LHYNFPAFAV GSVGRYLAPS RREIGHGMLA EKALECVLPS ENDFPYSIRV
460 470 480 490 500
VSEILDSNGS SSQATICASS MALMSAGVPL KSLVAGVAMG LIVDDIDKIN
510 520 530 540 550
HYTILSDIEG LEDYQGDIDF KIAGTKVGIT ALQLDIKIKG ITLEIFEKVL
560 570 580 590 600
EQAKKDRIKI LNEMEKVINK SRNEVSKYAP KVKMILIKPE KIRDIIGSGG
610 620 630 640 650
KIINQIIEKH DNVKIDIMQD GKIYIMHQNM EIVDLTVTYI QNFLKKIKVE
660 670 680 690 700
NVYEVKILRF VKDKMDKTFG AIAEIFPGIE GFIHISKLEN YKVDKVEDVL
710 720
KIGQIILVKC IKINERGQID LSKKDVFK
Length:728
Mass (Da):82,279
Last modified:September 2, 2008 - v1
Checksum:i84D02E226ACDBDE1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU469464 Genomic DNA. Translation: CAP18568.1.
RefSeqiYP_002004412.1. NC_011047.1.

Genome annotation databases

EnsemblBacteriaiCAP18568; CAP18568; ATP_00381.
GeneIDi6450674.
KEGGipml:ATP_00381.
PATRICi31995025. VBICanPhy52977_0393.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU469464 Genomic DNA. Translation: CAP18568.1 .
RefSeqi YP_002004412.1. NC_011047.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 37692.ATP_00381.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAP18568 ; CAP18568 ; ATP_00381 .
GeneIDi 6450674.
KEGGi pml:ATP_00381.
PATRICi 31995025. VBICanPhy52977_0393.

Phylogenomic databases

eggNOGi COG1185.
HOGENOMi HOG000218326.
KOi K00962.
OMAi GTENTIC.
OrthoDBi EOG6WT8CC.

Enzyme and pathway databases

BioCyci PMAL37692:GC0T-415-MONOMER.

Family and domain databases

Gene3Di 1.10.10.400. 1 hit.
2.40.50.140. 1 hit.
3.30.1370.10. 1 hit.
3.30.230.70. 2 hits.
HAMAPi MF_01595. PNPase.
InterProi IPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
IPR012340. NA-bd_OB-fold.
IPR012162. PNPase.
IPR027408. PNPase/RNase_PH_dom.
IPR015848. PNPase_PH_RNA-bd_bac/org-type.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR022967. S1_dom.
[Graphical view ]
PANTHERi PTHR11252. PTHR11252. 1 hit.
Pfami PF00013. KH_1. 1 hit.
PF03726. PNPase. 1 hit.
PF01138. RNase_PH. 2 hits.
PF03725. RNase_PH_C. 2 hits.
PF00575. S1. 1 hit.
[Graphical view ]
PIRSFi PIRSF005499. PNPase. 1 hit.
SMARTi SM00322. KH. 1 hit.
SM00316. S1. 1 hit.
[Graphical view ]
SUPFAMi SSF46915. SSF46915. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF54211. SSF54211. 2 hits.
SSF54791. SSF54791. 1 hit.
SSF55666. SSF55666. 2 hits.
TIGRFAMsi TIGR03591. polynuc_phos. 1 hit.
PROSITEi PS50084. KH_TYPE_1. 1 hit.
PS50126. S1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The linear chromosome of the plant-pathogenic mycoplasma 'Candidatus Phytoplasma mali'."
    Kube M., Schneider B., Kuhl H., Dandekar T., Heitmann K., Migdoll A.M., Reinhardt R., Seemueller E.
    BMC Genomics 9:306-306(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AT.

Entry informationi

Entry nameiPNP_PHYMT
AccessioniPrimary (citable) accession number: B3QZG1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 1, 2009
Last sequence update: September 2, 2008
Last modified: October 29, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3