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B3QZC7 (AROA_CHLT3) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-phosphoshikimate 1-carboxyvinyltransferase
EC=2.5.1.19
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase
Short name=EPSP synthase
Short name=EPSPS
Gene names
Name:aroA
Ordered Locus Names:Ctha_1357
OrganismChloroherpeton thalassium (strain ATCC 35110 / GB-78) [Complete proteome] [HAMAP]
Taxonomic identifier517418 [NCBI]
Taxonomic lineageBacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chloroherpeton

Protein attributes

Sequence length435 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-phosphoshikimate 1-carboxyvinyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4354353-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
PRO_1000099683

Sequences

Sequence LengthMass (Da)Tools
B3QZC7 [UniParc].

Last modified September 2, 2008. Version 1.
Checksum: 0AC8B846BC9CAC5D

FASTA43547,621
        10         20         30         40         50         60 
MKTFNGTFFN LPPDKSISHR TALIGALSNG ITEITNYSAG LDNQTTLSVL QSLGVDIQQE 

        70         80         90        100        110        120 
SFLTNDGYEQ RKVVIKSSGL WSLSRSKREL MCNNSGSTIR MLSGILAAQP FRTTLVGDHS 

       130        140        150        160        170        180 
LMKRPMRRVA EPLTQMGASI KLSETGAPPI EIEGKKPLSP IQFYQKIPSA QVKSLVIFAA 

       190        200        210        220        230        240 
LHADGISEII EPIQTRNHTE LMLGLEPELQ PDGSRKIVIE GQKNIEAKPF TVPADPSGAC 

       250        260        270        280        290        300 
FLVALGLLSG KSDIRLKNVG LNHTRAGYLS LLREAGAKLP TENNRTIGGE LLGDIIISND 

       310        320        330        340        350        360 
YITKPLRIND AQIVSDIIDE IPMLAVLSAM ATGEFELHHA AELRAKESDR IHALVMNLQR 

       370        380        390        400        410        420 
LGFVCEEYKD GFCVTGRTHN PTGTIEITTF YDHRIAMSFA IAGHFSNAEI QLDDNSSIAV 

       430 
SFPNFFSLID SMQKT

« Hide

References

[1]"Complete sequence of Chloroherpeton thalassium ATCC 35110."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Liu Z., Li T., Zhao F. expand/collapse author list , Overmann J., Bryant D.A., Richardson P.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 35110 / GB-78.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001100 Genomic DNA. Translation: ACF13820.1.
RefSeqYP_001996267.1. NC_011026.1.

3D structure databases

ProteinModelPortalB3QZC7.
ModBaseSearch...

Protein-protein interaction databases

STRINGB3QZC7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6422423.
GenomeReviewsGene locus Ctha_1357 in contig CP001100_GR.
KEGGcts:Ctha_1357.
PATRIC21431561. VBIChlTha99257_1587.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG646626.
OMALECANIS.
ProtClustDBPRK02427.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. False negative.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROA_CHLT3
AccessionPrimary (citable) accession number: B3QZC7
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 2, 2008
Last modified: January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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