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Protein

ATP synthase subunit alpha

Gene

atpA

Organism
Chloroherpeton thalassium (strain ATCC 35110 / GB-78)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.UniRule annotation

Catalytic activityi

ATP + H2O + H+(In) = ADP + phosphate + H+(Out).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei393Required for activityUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi171 – 178ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processATP synthesis, Hydrogen ion transport, Ion transport, Transport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCTHA517418:G1GC9-910-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
ATP synthase subunit alphaUniRule annotation (EC:3.6.3.14UniRule annotation)
Alternative name(s):
ATP synthase F1 sector subunit alphaUniRule annotation
F-ATPase subunit alphaUniRule annotation
Gene namesi
Name:atpAUniRule annotation
Ordered Locus Names:Ctha_0873
OrganismiChloroherpeton thalassium (strain ATCC 35110 / GB-78)
Taxonomic identifieri517418 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChloroherpeton
Proteomesi
  • UP000001208 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, CF(1), Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001433551 – 537ATP synthase subunit alphaAdd BLAST537

Proteomic databases

PRIDEiB3QWX7

Interactioni

Subunit structurei

F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has four main subunits: a, b, b' and c.UniRule annotation

Protein-protein interaction databases

STRINGi517418.Ctha_0873

Structurei

3D structure databases

SMRiB3QWX7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATPase alpha/beta chains family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDG Bacteria
COG0056 LUCA
HOGENOMiHOG000130111
KOiK02111
OMAiGNAQIKS
OrthoDBiPOG091H01QH

Family and domain databases

CDDicd01132 F1_ATPase_alpha, 1 hit
Gene3Di1.20.150.20, 1 hit
2.40.30.20, 1 hit
HAMAPiMF_01346 ATP_synth_alpha_bact, 1 hit
InterProiView protein in InterPro
IPR023366 ATP_synth_asu-like_sf
IPR000793 ATP_synth_asu_C
IPR038376 ATP_synth_asu_C_sf
IPR033732 ATP_synth_F1_a
IPR005294 ATP_synth_F1_asu
IPR020003 ATPase_a/bsu_AS
IPR004100 ATPase_F1/V1/A1_a/bsu_N
IPR036121 ATPase_F1/V1/A1_a/bsu_N_sf
IPR000194 ATPase_F1/V1/A1_a/bsu_nucl-bd
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00006 ATP-synt_ab, 1 hit
PF00306 ATP-synt_ab_C, 1 hit
PF02874 ATP-synt_ab_N, 1 hit
PIRSFiPIRSF039088 F_ATPase_subunit_alpha, 1 hit
SUPFAMiSSF50615 SSF50615, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00962 atpA, 1 hit
PROSITEiView protein in PROSITE
PS00152 ATPASE_ALPHA_BETA, 1 hit

Sequencei

Sequence statusi: Complete.

B3QWX7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTAVRPDEI SAILRKQLSG FDSEVDVYDV GTVLQVGDGI ARIYGLSKVA
60 70 80 90 100
AGELVEFPHN VTGMVLNLEE DNVGAVLFGS SDLIKEGDTV KRTKILASIP
110 120 130 140 150
VGEAMLGRVI NPLGEPIDGK GAIKTEIRLP LERRAPGVIF RHPVKEPLQT
160 170 180 190 200
GLKAIDSMIP IGRGQRELII GDRQTGKTAV AIDTIINQKA SHTKEAQEKG
210 220 230 240 250
AKPVYCIYVA TGQKASTVAQ VVNILEKHGA MEYTTVISAT ASDPAPLQFI
260 270 280 290 300
SPYAGATLGE YFRDTGRHAL VIYDDLSKQA VAYRQVSLLL RRPPGREAYP
310 320 330 340 350
GDVFYLHSRL LERAARITND DALAKQMNDL PDSIKPMAKG GGSLTALPII
360 370 380 390 400
ETQAGDVSAY IPTNVISITD GQIFLESNLF NSGQRPAINV GISVSRVGGS
410 420 430 440 450
AQIKGMKKVA GTLRLDLAQY RELEAFAKFG SDLDKATQAQ LTRGGRLVEI
460 470 480 490 500
LKQGQYVPMA VEKQVAILFV GTQGILDTLP ANLVRKFEVA FLEMLELKHK
510 520 530
DILNTIATAG QMDADTQKKL RQVAEQFLET FKQANVK
Length:537
Mass (Da):58,157
Last modified:September 2, 2008 - v1
Checksum:i2C04CF2D640AFE96
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001100 Genomic DNA Translation: ACF13341.1
RefSeqiWP_012499425.1, NC_011026.1

Genome annotation databases

EnsemblBacteriaiACF13341; ACF13341; Ctha_0873
KEGGicts:Ctha_0873

Similar proteinsi

Entry informationi

Entry nameiATPA_CHLT3
AccessioniPrimary (citable) accession number: B3QWX7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 2, 2008
Last modified: March 28, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health