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B3QW90 (B3QW90_CHLT3) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Dihydroorotate dehydrogenase HAMAP MF_00224
Short name=DHOD HAMAP MF_00224
Short name=DHODase HAMAP MF_00224
Short name=DHOdehase HAMAP MF_00224
EC=1.3.-.- HAMAP MF_00224
Gene names
Name:pyrD HAMAP MF_00224
Ordered Locus Names:Ctha_0734
OrganismChloroherpeton thalassium (strain ATCC 35110 / GB-78) [Complete proteome] [HAMAP]
Taxonomic identifier517418 [NCBI]
Taxonomic lineageBacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chloroherpeton

Protein attributes

Sequence length311 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the conversion of dihydroorotate to orotate By similarity. HAMAP MF_00224

Catalytic activity

(S)-dihydroorotate + acceptor = orotate + reduced acceptor. HAMAP MF_00224

Cofactor

Binds 1 FMN per subunit By similarity. HAMAP MF_00224 SAAS SAAS012135

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway. HAMAP MF_00224

Subcellular location

Cytoplasm By similarity HAMAP MF_00224.

Sequence similarities

Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. HAMAP MF_00224

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1361Nucleophile By similarity PIRSR PIRSR000164-1

Sequences

Sequence LengthMass (Da)Tools
B3QW90 [UniParc].

Last modified September 2, 2008. Version 1.
Checksum: 94F403FC07C575B1

FASTA31133,365
        10         20         30         40         50         60 
MNVIVENPVA VSLGRGLDLK NPVMLASGTV SYGEELYKLN DLSAIGGIVT KAISLEPRQG 

        70         80         90        100        110        120 
NAPQRLVETH AGVLNAIGLA NIGVERFIQN KMPFLRSLDA RVVVNVVGGS IEDYCEVIKT 

       130        140        150        160        170        180 
LNEVEGIDGY EINLSCPNVK GECIIFGVDA HATHEITSAL REITDRHLMI KLTPNVTSIG 

       190        200        210        220        230        240 
SIAMAAEKAG ADSISLINTL VGMAVDYRTK KPLLRNVTGG LSGPAIKPVA VAKVWEASKS 

       250        260        270        280        290        300 
VNIPIIGMGG IADFEDAMEF FVVGASAVQI GTMNFVYPNI SSKIARRIEE YFRNTSDVPF 

       310 
HEYVGSLICT F

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References

[1]"Complete sequence of Chloroherpeton thalassium ATCC 35110."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Liu Z., Li T., Zhao F. expand/collapse author list , Overmann J., Bryant D.A., Richardson P.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 35110 / GB-78.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001100 Genomic DNA. Translation: ACF13203.1.
RefSeqYP_001995650.1. NC_011026.1.

3D structure databases

ProteinModelPortalB3QW90.
ModBaseSearch...

Protein-protein interaction databases

STRINGB3QW90.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6421780.
GenomeReviewsGene locus Ctha_0734 in contig CP001100_GR.
KEGGcts:Ctha_0734.
PATRIC21430075. VBIChlTha99257_0864.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG472415.
OMAVALRMVW.
ProtClustDBCLSK637846.

Family and domain databases

HAMAPMF_00224. DHO_dh_type1.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR005720. Dihydroorotate_DH.
IPR024920. Dihydroorotate_DH_1.
IPR012135. Dihydroorotate_DH_1_2.
IPR001295. Dihydroorotate_DH_CS.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK00226.
PfamPF01180. DHO_dh. 1 hit.
[Graphical view]
PIRSFPIRSF000164. DHO_oxidase. 1 hit.
TIGRFAMsTIGR01037. PyrD_sub1_fam. 1 hit.
PROSITEPS00912. DHODEHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB3QW90_CHLT3
AccessionPrimary (citable) accession number: B3QW90
Entry history
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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