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B3QVV1

- B3QVV1_CHLT3

UniProt

B3QVV1 - B3QVV1_CHLT3

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Protein
Putative K(+)-stimulated pyrophosphate-energized sodium pump
Gene
hppA, Ctha_0689
Organism
Chloroherpeton thalassium (strain ATCC 35110 / GB-78)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na+ movement across the membrane By similarity.UniRule annotation

Catalytic activityi

Diphosphate + H2O = 2 phosphate.UniRule annotation

Cofactori

Magnesium By similarity.UniRule annotation

Enzyme regulationi

Requires K+ for maximal activity By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei473 – 4731Determinant of potassium dependence By similarityUniRule annotation

GO - Molecular functioni

  1. hydrogen-translocating pyrophosphatase activity Source: UniProtKB-HAMAP
  2. inorganic diphosphatase activity Source: UniProtKB-HAMAP
  3. magnesium ion binding Source: UniProtKB-HAMAP
  4. potassium ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. proton transport Source: InterPro
  2. sodium ion transport Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotationImported

Keywords - Biological processi

Ion transport, Sodium transportUniRule annotation, Transport

Keywords - Ligandi

MagnesiumUniRule annotation, PotassiumUniRule annotation, Sodium

Enzyme and pathway databases

BioCyciCTHA517418:GHTO-693-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative K(+)-stimulated pyrophosphate-energized sodium pumpUniRule annotation (EC:3.6.1.1UniRule annotation)
Alternative name(s):
Membrane-bound sodium-translocating pyrophosphatase
Pyrophosphate-energized inorganic pyrophosphatase
Gene namesi
Name:hppAUniRule annotation
Ordered Locus Names:Ctha_0689Imported
OrganismiChloroherpeton thalassium (strain ATCC 35110 / GB-78)Imported
Taxonomic identifieri517418 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChloroherpeton
ProteomesiUP000001208: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei1 – 2121Helical; By similarityUniRule annotation
Add
BLAST
Transmembranei55 – 7521Helical; By similarityUniRule annotation
Add
BLAST
Transmembranei81 – 10121Helical; By similarityUniRule annotation
Add
BLAST
Transmembranei132 – 15221Helical; By similarityUniRule annotation
Add
BLAST
Transmembranei167 – 18721Helical; By similarityUniRule annotation
Add
BLAST
Transmembranei243 – 26321Helical; By similarityUniRule annotation
Add
BLAST
Transmembranei268 – 28821Helical; By similarityUniRule annotation
Add
BLAST
Transmembranei304 – 32421Helical; By similarityUniRule annotation
Add
BLAST
Transmembranei340 – 36021Helical; By similarityUniRule annotation
Add
BLAST
Transmembranei377 – 39721Helical; By similarityUniRule annotation
Add
BLAST
Transmembranei399 – 41921Helical; By similarityUniRule annotation
Add
BLAST
Transmembranei420 – 44021Helical; By similarityUniRule annotation
Add
BLAST
Transmembranei475 – 49521Helical; By similarityUniRule annotation
Add
BLAST
Transmembranei510 – 53021Helical; By similarityUniRule annotation
Add
BLAST
Transmembranei574 – 59421Helical; By similarityUniRule annotation
Add
BLAST
Transmembranei599 – 61921Helical; By similarityUniRule annotation
Add
BLAST
Transmembranei669 – 68921Helical; By similarityUniRule annotation
Add
BLAST

GO - Cellular componenti

  1. integral component of plasma membrane Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cell membraneUniRule annotation, Membrane

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi517418.Ctha_0689.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiCOG3808.
HOGENOMiHOG000007098.
KOiK15987.
OMAiPVESIAY.
OrthoDBiEOG6TXQSF.

Family and domain databases

HAMAPiMF_01129. PPase_energized_pump.
InterProiIPR004131. PPase-energised_H-pump.
[Graphical view]
PfamiPF03030. H_PPase. 1 hit.
[Graphical view]
PIRSFiPIRSF001265. H+-PPase. 1 hit.
TIGRFAMsiTIGR01104. V_PPase. 1 hit.

Sequencei

Sequence statusi: Complete.

B3QVV1-1 [UniParc]FASTAAdd to Basket

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MDTLIYAIPA AGVISLLYAS LKTSWVTKQP TGTQEMTEIA GHIAEGAKAF    50
LQREYRILII FVVAVAALLA FANMGRTDSS WLVAVSFVIG ALCSAGAGFI 100
GMTVATKANV RTTHAARTGL AEALNVAFSG GLVMGLSVVG LGVLGLSVLF 150
IVYSNLFDEV GRVINVISGF SLGASSIALF ARVGGGIYTK AADVGADLAG 200
KVYEGIPEDD PRNPATIADN VGDNVGDVAG MGADLFESYV GSIIGTMVLG 250
AAFVPVFQEM GVMPTAAVLL PLVLAGVGII VSILGSFFVK VKEGGNPQTA 300
LNTGEFGASG VMAVLSYFII TMFLPEKWEL DGMTYTSQNI FFAVLIGLVS 350
GVLIGIITEY YCSTHNKPVL GIAYQSVTGA ATNIIAGLGV GMFSTGFPII 400
VLSIAIVASH YFAGLFGIAI AALGMLSVTG IQLAVDAYGP ISDNAGGIAE 450
MSGMPPEVRE RTDTLDAVGN TTAAIGKGFA IGSAALTALA LFAAFMQQAN 500
ISSIDISHPV IMAGLLIGAM LPFVFSAMAM GAVGRAARDM ITEVGRQFRE 550
IKGLREGTAK AEYAKCVDIS TKAALREMIL PGLMGVFVPV IVGFTSKDML 600
GGLLAGVTSS GVLMAIFQSN AGGAWDNAKK RIEGKLEIDG VMYGKGSDVH 650
KAAVVGDTVG DPFKDTSGPS LNILMKLIAV VALVIAPLL 689
Length:689
Mass (Da):70,969
Last modified:September 2, 2008 - v1
Checksum:i62B677120D391198
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001100 Genomic DNA. Translation: ACF13158.1.
RefSeqiYP_001995605.1. NC_011026.1.

Genome annotation databases

EnsemblBacteriaiACF13158; ACF13158; Ctha_0689.
GeneIDi6421734.
KEGGicts:Ctha_0689.
PATRICi21429959. VBIChlTha99257_0807.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001100 Genomic DNA. Translation: ACF13158.1 .
RefSeqi YP_001995605.1. NC_011026.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 517418.Ctha_0689.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACF13158 ; ACF13158 ; Ctha_0689 .
GeneIDi 6421734.
KEGGi cts:Ctha_0689.
PATRICi 21429959. VBIChlTha99257_0807.

Phylogenomic databases

eggNOGi COG3808.
HOGENOMi HOG000007098.
KOi K15987.
OMAi PVESIAY.
OrthoDBi EOG6TXQSF.

Enzyme and pathway databases

BioCyci CTHA517418:GHTO-693-MONOMER.

Family and domain databases

HAMAPi MF_01129. PPase_energized_pump.
InterProi IPR004131. PPase-energised_H-pump.
[Graphical view ]
Pfami PF03030. H_PPase. 1 hit.
[Graphical view ]
PIRSFi PIRSF001265. H+-PPase. 1 hit.
TIGRFAMsi TIGR01104. V_PPase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Chloroherpeton thalassium ATCC 35110."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Liu Z., Li T., Zhao F.
    , Overmann J., Bryant D.A., Richardson P.
    Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35110 / GB-78.

Entry informationi

Entry nameiB3QVV1_CHLT3
AccessioniPrimary (citable) accession number: B3QVV1
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: May 14, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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