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B3QVV1 (B3QVV1_CHLT3) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Putative K(+)-stimulated pyrophosphate-energized sodium pump HAMAP-Rule MF_01129

EC=3.6.1.1 HAMAP-Rule MF_01129
Alternative name(s):
Membrane-bound sodium-translocating pyrophosphatase HAMAP-Rule MF_01129
Pyrophosphate-energized inorganic pyrophosphatase HAMAP-Rule MF_01129
Gene names
Name:hppA HAMAP-Rule MF_01129
Ordered Locus Names:Ctha_0689 EMBL ACF13158.1
OrganismChloroherpeton thalassium (strain ATCC 35110 / GB-78) [Complete proteome] [HAMAP] EMBL ACF13158.1
Taxonomic identifier517418 [NCBI]
Taxonomic lineageBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChloroherpeton

Protein attributes

Sequence length689 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na+ movement across the membrane By similarity. HAMAP-Rule MF_01129

Catalytic activity

Diphosphate + H2O = 2 phosphate. HAMAP-Rule MF_01129

Cofactor

Magnesium By similarity. HAMAP-Rule MF_01129

Enzyme regulation

Requires K+ for maximal activity By similarity. HAMAP-Rule MF_01129

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_01129

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01129.

Sequence similarities

Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily. [View classification] HAMAP-Rule MF_01129

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Transmembrane1 – 2121Helical; By similarity HAMAP-Rule MF_01129
Transmembrane55 – 7521Helical; By similarity HAMAP-Rule MF_01129
Transmembrane81 – 10121Helical; By similarity HAMAP-Rule MF_01129
Transmembrane132 – 15221Helical; By similarity HAMAP-Rule MF_01129
Transmembrane167 – 18721Helical; By similarity HAMAP-Rule MF_01129
Transmembrane243 – 26321Helical; By similarity HAMAP-Rule MF_01129
Transmembrane268 – 28821Helical; By similarity HAMAP-Rule MF_01129
Transmembrane304 – 32421Helical; By similarity HAMAP-Rule MF_01129
Transmembrane340 – 36021Helical; By similarity HAMAP-Rule MF_01129
Transmembrane377 – 39721Helical; By similarity HAMAP-Rule MF_01129
Transmembrane399 – 41921Helical; By similarity HAMAP-Rule MF_01129
Transmembrane420 – 44021Helical; By similarity HAMAP-Rule MF_01129
Transmembrane475 – 49521Helical; By similarity HAMAP-Rule MF_01129
Transmembrane510 – 53021Helical; By similarity HAMAP-Rule MF_01129
Transmembrane574 – 59421Helical; By similarity HAMAP-Rule MF_01129
Transmembrane599 – 61921Helical; By similarity HAMAP-Rule MF_01129
Transmembrane669 – 68921Helical; By similarity HAMAP-Rule MF_01129

Sites

Site4731Determinant of potassium dependence By similarity HAMAP-Rule MF_01129

Sequences

Sequence LengthMass (Da)Tools
B3QVV1 [UniParc].

Last modified September 2, 2008. Version 1.
Checksum: 62B677120D391198

FASTA68970,969
        10         20         30         40         50         60 
MDTLIYAIPA AGVISLLYAS LKTSWVTKQP TGTQEMTEIA GHIAEGAKAF LQREYRILII 

        70         80         90        100        110        120 
FVVAVAALLA FANMGRTDSS WLVAVSFVIG ALCSAGAGFI GMTVATKANV RTTHAARTGL 

       130        140        150        160        170        180 
AEALNVAFSG GLVMGLSVVG LGVLGLSVLF IVYSNLFDEV GRVINVISGF SLGASSIALF 

       190        200        210        220        230        240 
ARVGGGIYTK AADVGADLAG KVYEGIPEDD PRNPATIADN VGDNVGDVAG MGADLFESYV 

       250        260        270        280        290        300 
GSIIGTMVLG AAFVPVFQEM GVMPTAAVLL PLVLAGVGII VSILGSFFVK VKEGGNPQTA 

       310        320        330        340        350        360 
LNTGEFGASG VMAVLSYFII TMFLPEKWEL DGMTYTSQNI FFAVLIGLVS GVLIGIITEY 

       370        380        390        400        410        420 
YCSTHNKPVL GIAYQSVTGA ATNIIAGLGV GMFSTGFPII VLSIAIVASH YFAGLFGIAI 

       430        440        450        460        470        480 
AALGMLSVTG IQLAVDAYGP ISDNAGGIAE MSGMPPEVRE RTDTLDAVGN TTAAIGKGFA 

       490        500        510        520        530        540 
IGSAALTALA LFAAFMQQAN ISSIDISHPV IMAGLLIGAM LPFVFSAMAM GAVGRAARDM 

       550        560        570        580        590        600 
ITEVGRQFRE IKGLREGTAK AEYAKCVDIS TKAALREMIL PGLMGVFVPV IVGFTSKDML 

       610        620        630        640        650        660 
GGLLAGVTSS GVLMAIFQSN AGGAWDNAKK RIEGKLEIDG VMYGKGSDVH KAAVVGDTVG 

       670        680 
DPFKDTSGPS LNILMKLIAV VALVIAPLL 

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References

[1]"Complete sequence of Chloroherpeton thalassium ATCC 35110."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Liu Z., Li T., Zhao F. expand/collapse author list , Overmann J., Bryant D.A., Richardson P.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 35110 / GB-78.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001100 Genomic DNA. Translation: ACF13158.1.
RefSeqYP_001995605.1. NC_011026.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING517418.Ctha_0689.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACF13158; ACF13158; Ctha_0689.
GeneID6421734.
KEGGcts:Ctha_0689.
PATRIC21429959. VBIChlTha99257_0807.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3808.
HOGENOMHOG000007098.
KOK15987.
OMAHIAQAST.
OrthoDBEOG6TXQSF.
ProtClustDBPRK00733.

Enzyme and pathway databases

BioCycCTHA517418:GHTO-693-MONOMER.

Family and domain databases

HAMAPMF_01129. PPase_energized_pump.
InterProIPR004131. PPase-energised_H-pump.
[Graphical view]
PfamPF03030. H_PPase. 1 hit.
[Graphical view]
PIRSFPIRSF001265. H+-PPase. 1 hit.
TIGRFAMsTIGR01104. V_PPase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB3QVV1_CHLT3
AccessionPrimary (citable) accession number: B3QVV1
Entry history
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: April 16, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)