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B3QTV0 (B3QTV0_CHLT3) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Non-canonical purine NTP pyrophosphatase HAMAP MF_01405
EC=3.6.1.19 HAMAP MF_01405
Alternative name(s):
Non-standard purine NTP pyrophosphatase HAMAP MF_01405
Nucleoside-triphosphate diphosphatase HAMAP MF_01405
Nucleoside-triphosphate pyrophosphatase HAMAP MF_01405
Gene names
Ordered Locus Names:Ctha_1841
OrganismChloroherpeton thalassium (strain ATCC 35110 / GB-78) [Complete proteome] [HAMAP]
Taxonomic identifier517418 [NCBI]
Taxonomic lineageBacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chloroherpeton

Protein attributes

Sequence length227 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP/dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions By similarity. HAMAP MF_01405

Catalytic activity

A nucleoside triphosphate + H2O = a nucleotide + diphosphate. HAMAP MF_01405 SAAS SAAS020922

Cofactor

Binds 1 divalent metal cation ion per subunit; can use either magnesium or manganese By similarity. HAMAP MF_01405 SAAS SAAS020922

Subunit structure

Homodimer By similarity. HAMAP MF_01405 SAAS SAAS020922

Sequence similarities

Belongs to the HAM1 NTPase family. HAMAP MF_01405 RuleBase RU003781

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region18 – 236Substrate binding By similarity HAMAP MF_01405
Region87 – 882Substrate binding By similarity HAMAP MF_01405

Sites

Metal binding531Magnesium or manganese By similarity HAMAP MF_01405
Metal binding871Magnesium or manganese By similarity HAMAP MF_01405
Binding site1841Substrate By similarity HAMAP MF_01405
Binding site2041Substrate By similarity HAMAP MF_01405
Binding site2101Substrate By similarity HAMAP MF_01405

Sequences

Sequence LengthMass (Da)Tools
B3QTV0 [UniParc].

Last modified September 2, 2008. Version 1.
Checksum: 6416ACF4802A2F34

FASTA22724,887
        10         20         30         40         50         60 
MIDYPEIPAG KTALILATGN RDKVAEIKPL LMPIAEHLVI FSLADLPKLP EVEENAPTLE 

        70         80         90        100        110        120 
GNAKKKAKEI FEHTQSHFAN LITLADDTGL EVAALNGAPG VYSARYAATP QKEKPSYADN 

       130        140        150        160        170        180 
VDKLLSDMQN LTNRTARFRT VIALVSRTNF GKESSPIYFE EVLEATVQGE ITYEKHGSSG 

       190        200        210        220 
FGYDPIFRVS EVGKTFAELS VSEKNQISHR GKAVQTAVKF LTKCFLG

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References

[1]"Complete sequence of Chloroherpeton thalassium ATCC 35110."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Liu Z., Li T., Zhao F. expand/collapse author list , Overmann J., Bryant D.A., Richardson P.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 35110 / GB-78.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001100 Genomic DNA. Translation: ACF14298.1.
RefSeqYP_001996745.1. NC_011026.1.

3D structure databases

ProteinModelPortalB3QTV0.
ModBaseSearch...

Protein-protein interaction databases

STRINGB3QTV0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6422919.
GenomeReviewsGene locus Ctha_1841 in contig CP001100_GR.
KEGGcts:Ctha_1841.
PATRIC21432719. VBIChlTha99257_2155.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG697237.
OMAYSKRYDQ.
ProtClustDBPRK14826.

Family and domain databases

HAMAPMF_01405. Non_canon_purine_NTPase.
[Tree]
InterProIPR002637. Ham1p-like.
IPR020922. Nucleoside-triphosphatase.
[Graphical view]
KOK02428.
PANTHERPTHR11067. Ham1p_like. 1 hit.
PfamPF01725. Ham1p_like. 1 hit.
[Graphical view]
TIGRFAMsTIGR00042. TIGR00042. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB3QTV0_CHLT3
AccessionPrimary (citable) accession number: B3QTV0
Entry history
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: December 14, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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