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B3QT02 (B3QT02_CHLT3) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
1-deoxy-D-xylulose-5-phosphate synthase HAMAP MF_00315
EC=2.2.1.7 HAMAP MF_00315
Alternative name(s):
1-deoxyxylulose-5-phosphate synthase HAMAP MF_00315
Gene names
Name:dxs HAMAP MF_00315
Ordered Locus Names:Ctha_0174
OrganismChloroherpeton thalassium (strain ATCC 35110 / GB-78) [Complete proteome] [HAMAP]
Taxonomic identifier517418 [NCBI]
Taxonomic lineageBacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chloroherpeton

Protein attributes

Sequence length647 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) By similarity. HAMAP MF_00315 SAAS SAAS005477

Catalytic activity

Pyruvate + D-glyceraldehyde 3-phosphate = 1-deoxy-D-xylulose 5-phosphate + CO2. HAMAP MF_00315 SAAS SAAS005477

Cofactor

Binds 1 thiamine pyrophosphate per subunit By similarity. HAMAP MF_00315 SAAS SAAS005477

Pathway

Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5-phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1. HAMAP MF_00315 SAAS SAAS005477

Subunit structure

Homodimer By similarity. HAMAP MF_00315 SAAS SAAS005477

Sequence similarities

Belongs to the transketolase family. DXPS subfamily. HAMAP MF_00315

Sequences

Sequence LengthMass (Da)Tools
B3QT02 [UniParc].

Last modified September 2, 2008. Version 1.
Checksum: C79C24907BD430F5

FASTA64770,436
        10         20         30         40         50         60 
MNPNLKESEE LASFGTYLSK IDSPEDLRKF SIEELPAIAQ ECRELVIDAV SKNGGHFGSS 

        70         80         90        100        110        120 
LGVAELSVAL HYAYNTPKDQ IIWDVGHQAY VHKILTGRKN FFYSNRKYGG VSGFPKRAES 

       130        140        150        160        170        180 
CYDAFGVGHA STSISAATGM AAARDLAHED FKVVAVIGDG SMTGGMAFEG MNHLGHLKTD 

       190        200        210        220        230        240 
VTVILNDNRM SIDPNVGGLR EYLTDITTNF TYNKIRRDIW QTLSKFDNEI GSTARRLVRG 

       250        260        270        280        290        300 
IEDGLKAALT PGSYFEALGF RYFGPIDGHD VGHLARVLTE IRGLPHPKLL HIVTVKGKGF 

       310        320        330        340        350        360 
APAEANQSKW HAQSGAFDKV TGVSLKKADP NAAPKYQDVF GDAITKIAGK DQRVVGVTAA 

       370        380        390        400        410        420 
MPSGTSLKKL GEKYPERFFD VGIAEPHAVT FAAGMAVHGF KPVCAIYSTF LQRAYDQIIH 

       430        440        450        460        470        480 
DVALQKLNVI FAIDRAGLVG ADGPTHHGVF DLSFLRMIPN MVVMAPMHEQ ELCDMLLTAV 

       490        500        510        520        530        540 
KYENGPVAVR YPRGNGLGMA LQEFKQLPIG KGEVLRDGEE IAILGIGLMS NVALEAAALL 

       550        560        570        580        590        600 
EAQGVSPLVA NMRFVKPIDT ELLDAICARF DRIVTIEENT VIGGFGSAVC EYLQEKGHRN 

       610        620        630        640 
RVLTLGIPDR FIEHGSVADL HREIGLDAQG VVKRILEFAH SEDIVAM

« Hide

References

[1]"Complete sequence of Chloroherpeton thalassium ATCC 35110."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Liu Z., Li T., Zhao F. expand/collapse author list , Overmann J., Bryant D.A., Richardson P.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 35110 / GB-78.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001100 Genomic DNA. Translation: ACF12645.1.
RefSeqYP_001995092.1. NC_011026.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB3QT02.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6421063.
GenomeReviewsGene locus Ctha_0174 in contig CP001100_GR.
KEGGcts:Ctha_0174.
PATRIC21428749. VBIChlTha99257_0205.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG571647.
OMAIMEYAYL.
ProtClustDBPRK05444.

Family and domain databases

HAMAPMF_00315. DXP_synth.
[Tree]
InterProIPR005477. Dxylulose-5-P_synthase.
IPR011766. TPP_enzyme-bd_C.
IPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR015941. Transketolase-like_C.
IPR005475. Transketolase-like_Pyr-bd.
IPR020826. Transketolase_BS.
IPR005476. Transketolase_C.
IPR005474. Transketolase_N.
[Graphical view]
Gene3DG3DSA:3.40.50.920. Transketo_C_like. 1 hit.
KOK01662.
PfamPF02775. TPP_enzyme_C. 1 hit.
PF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
[Graphical view]
SMARTSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMSSF52922. Transketo_C_like. 1 hit.
TIGRFAMsTIGR00204. Dxs. 1 hit.
PROSITEPS00801. TRANSKETOLASE_1. 1 hit.
PS00802. TRANSKETOLASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB3QT02_CHLT3
AccessionPrimary (citable) accession number: B3QT02
Entry history
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: December 14, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info