B3QSL3 (B3QSL3_CHLT3) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lipid-A-disaccharide synthase EMBL ACF14060.1

Gene names

Ordered Locus Names:

Ctha_1602

Organism

Chloroherpeton thalassium (strain ATCC 35110 / GB-78) [Complete proteome] [HAMAP]

Taxonomic identifier

517418 [NCBI]

Taxonomic lineage

Bacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chloroherpeton

Protein attributes

Sequence length	384 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B3QSL3 [UniParc]. Last modified September 2, 2008. Version 1. Checksum: 4DB74D1C8044E8AF	FASTA	384	42,872
	10 20 30 40 50 60 MQTLNKKLFI LAGEASGDLH ASGAVAELKK KQPDIDIFGI GGAKLQALGV RLIYHAEEVN 70 80 90 100 110 120 FMGFAEVIKH YPFLRKVFEK IKATILEEKP AAALLVDYPG MNLMLAEFLH KEGIPVIYYI 130 140 150 160 170 180 APQVWAWKEG RVKKIKQFVT RLLVVFDFEV DFFKKHGVKA EFVGHPIIEE LAEVNLPQKA 190 200 210 220 230 240 EFLLEKGISP EKKLIGLLPG SRRQELERIL PEMLSAAKLL RQKHDAVFLL GKAPNLPAEF 250 260 270 280 290 300 YQKFLEQSGV TPTFVTAYEV MQFSDAAMVT SGTVTLESLC FGLPMVVVYR TGTLNYQIGK 310 320 330 340 350 360 RLVKIQNFSL ANIVSKGLYS TTQTVPELLQ ENMTGEKIAA EIDKLLTNEN YRNTMRSSLL 370 380 DARANLGSLL PSKEVADAIL ETVS

References

[1]

"Complete sequence of Chloroherpeton thalassium ATCC 35110." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Liu Z., Li T., Zhao F. , Overmann J., Bryant D.A., Richardson P. Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35110 / GB-78.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001100 Genomic DNA. Translation: ACF14060.1.
RefSeq	YP_001996507.1. NC_011026.1.
3D structure databases
ProteinModelPortal	B3QSL3.
ModBase	Search...
Protein-protein interaction databases
STRING	B3QSL3.
Protein family/group databases
CAZy	GT19. Glycosyltransferase Family 19.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6422677.
GenomeReviews	Gene locus Ctha_1602 in contig CP001100_GR.
KEGG	cts:Ctha_1602.
PATRIC	21432163. VBIChlTha99257_1880.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG584837.
OMA	PDFNLGL.
ProtClustDB	CLSK637261.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B3QSL3_CHLT3

Accession

Primary (citable) accession number: B3QSL3

Entry history

Integrated into UniProtKB/TrEMBL:	September 2, 2008
Last sequence update:	September 2, 2008
Last modified:	December 14, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)