B3QQY3 (B3QQY3_CHLP8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Chromosomal replication initiator protein DnaA HAMAP MF_00377

Gene names

Name:	dnaA HAMAP MF_00377
Ordered Locus Names:	Cpar_0001

Organism

Chlorobaculum parvum (strain NCIB 8327) (Chlorobium vibrioforme subsp. thiosulfatophilum (strain DSM 263 / NCIB 8327)) [Complete proteome] [HAMAP]

Taxonomic identifier

517417 [NCBI]

Taxonomic lineage

Bacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobaculum

Protein attributes

Sequence length	493 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids By similarity. HAMAP MF_00377 RuleBase RU000577
Subcellular location	Cytoplasm By similarity HAMAP MF_00377.
Sequence similarities	Belongs to the DnaA family. HAMAP MF_00377 RuleBase RU004227

Ontologies

Keywords
Biological process	DNA replication HAMAP MF_00377 RuleBase RU000577
Cellular component	Cytoplasm HAMAP MF_00377
Ligand	ATP-binding HAMAP MF_00377 RuleBase RU000577 DNA-binding HAMAP MF_00377 RuleBase RU000577 Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA-dependent DNA replication initiation Inferred from electronic annotation. Source: HAMAP regulation of DNA replication Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP DNA replication origin binding Inferred from electronic annotation. Source: HAMAP nucleoside-triphosphatase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	195 – 202	8	ATP By similarity HAMAP MF_00377

Sequences

	Sequence		Length	Mass (Da)
	B3QQY3 [UniParc]. Last modified September 2, 2008. Version 1. Checksum: 2ECB94D759A67912	FASTA	493	55,615
	10 20 30 40 50 60 MPELIQQAPT GNLQATHSQS GSFAEKVWNA CLELIQENIN SLAFKTWFLP IRPLSFSGSE 70 80 90 100 110 120 LTIEVPSQFF YEWIEENYSV HVKQALRQVI GPEAKLMYSI VMDKSQGQPV TIELPHQNAH 130 140 150 160 170 180 APTESDTKPE RAQEPVSAER ERFERNRTKF ESNLNPKYTF STLIRGDCNS LAFAAAKSIA 190 200 210 220 230 240 QNPGQNAFNP LVIYGGVGLG KTHMMQAIGN SVLENRISGA VLYVSSEKFA IDFVNAIQNG 250 260 270 280 290 300 NIQEFSAFYR NIDVLIIDDI QFFAGKEKTQ EEIFHIFNTL HQANKQIILS ADRPIKEIKG 310 320 330 340 350 360 IEDRLISRFN WGLSTDIQAP DYETRKAIIQ SKLKQNGVNL DPAVIEFIAT NVTNNVRELE 370 380 390 400 410 420 GCIVKLLAAH SLDNQEIDLQ FTKSTLKDII RYNTKQLTLE TIEKAVCSFF SITPNDLKGK 430 440 450 460 470 480 SKKKEIAVGR QIAMYLSKDM TDSSLKTIGL HFGGRDHSTV IHALNTIEKK ITSSNEERKK 490 IEELKKRIEI MSM

References

[1]

"Complete sequence of Chlorobaculum parvum NCIB 8327." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Zhao F., Li T., Liu Z. , Overmann J., Bryant D.A., Richardson P. Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NCIB 8327.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001099 Genomic DNA. Translation: ACF10430.1.
RefSeq	YP_001997630.1. NC_011027.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B3QQY3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6421041.
GenomeReviews	Gene locus Cpar_0001 in contig CP001099_GR.
KEGG	cpc:Cpar_0001.
PATRIC	21363205. VBIChlPar72705_0001.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG695666.
OMA	CHTLNAL.
ProtClustDB	PRK00149.
Family and domain databases
HAMAP	MF_00377. DnaA_bact. [Tree]
InterPro	IPR003593. ATPase_AAA+_core. IPR001957. Chromosome_initiator_DnaA. IPR020591. Chromosome_initiator_DnaA-like. IPR018312. Chromosome_initiator_DnaA_CS. IPR013159. DnaA_C. IPR013317. DnaA_Hda. IPR010921. Trp_repressor/repl_initiator. [Graphical view]
Gene3D	G3DSA:1.10.1750.10. DnaA_C. 1 hit.
KO	K02313.
Pfam	PF00308. Bac_DnaA. 1 hit. PF08299. Bac_DnaA_C. 1 hit. [Graphical view]
PRINTS	PR00051. DNAA.
SMART	SM00382. AAA. 1 hit. SM00760. Bac_DnaA_C. 1 hit. [Graphical view]
SUPFAM	SSF48295. Trp_repress_rep. 1 hit.
TIGRFAMs	TIGR00362. DnaA. 1 hit.
PROSITE	PS01008. DNAA. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B3QQY3_CHLP8

Accession

Primary (citable) accession number: B3QQY3

Entry history

Integrated into UniProtKB/TrEMBL:	September 2, 2008
Last sequence update:	September 2, 2008
Last modified:	December 14, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)