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B3QQU3

- B3QQU3_CHLP8

UniProt

B3QQU3 - B3QQU3_CHLP8

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Protein

Alanine racemase

Gene

Cpar_0286

Organism
Chlorobaculum parvum (strain NCIB 8327) (Chlorobium vibrioforme subsp. thiosulfatophilum (strain DSM 263 / NCIB 8327))
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei51 – 511Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei152 – 1521SubstrateUniRule annotation
Active sitei280 – 2801Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei328 – 3281Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciCPAR517417:GH95-300-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Cpar_0286Imported
OrganismiChlorobaculum parvum (strain NCIB 8327) (Chlorobium vibrioforme subsp. thiosulfatophilum (strain DSM 263 / NCIB 8327))Imported
Taxonomic identifieri517417 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobaculum
ProteomesiUP000008811: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei51 – 511N6-(pyridoxal phosphate)lysineUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi517417.Cpar_0286.

Structurei

3D structure databases

ProteinModelPortaliB3QQU3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000031444.
KOiK01775.
OMAiAEININN.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3QQU3 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSADSRQNSS TADPAAPNLS EALISLGNLR HNLACIQAIS GSRCRIMGIV
60 70 80 90 100
KADAYGHGAA QVTATLEEEG IREFGVANIH EAIELKQSHR MQPESRILAF
110 120 130 140 150
ASPLAGHIEH YLEHDVEMTV CDHETVRTAE AKAAASGRRL RVQAKIDTGM
160 170 180 190 200
GRLGVTPEEA HSLLELIDRC PNLDLVGIYT HFAEGHKAGG FTARQLEQFL
210 220 230 240 250
DVTGGYEQRT GRTVLKHAAN SGAIVSTPSA RLDMVRPGIL LYGCHPMDAE
260 270 280 290 300
PTNVPVKPVM QFQCKVMFVK KVTAGTSISY SRTWSAPTST NIATLSAGYA
310 320 330 340 350
DGVHRTLSNK ATVSIGGNRY HQVGTVTMDQ TMVDLGQNRS VKVGDTAVLF
360 370 380
GWDGPSAGEQ AIAAGTISYE LLCAVSKRVK RVFV
Length:384
Mass (Da):41,236
Last modified:September 2, 2008 - v1
Checksum:i2036E6A2C17ED69A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001099 Genomic DNA. Translation: ACF10713.1.
RefSeqiWP_012501546.1. NC_011027.1.
YP_001997913.1. NC_011027.1.

Genome annotation databases

EnsemblBacteriaiACF10713; ACF10713; Cpar_0286.
GeneIDi6419199.
KEGGicpc:Cpar_0286.
PATRICi21363799. VBIChlPar72705_0284.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001099 Genomic DNA. Translation: ACF10713.1 .
RefSeqi WP_012501546.1. NC_011027.1.
YP_001997913.1. NC_011027.1.

3D structure databases

ProteinModelPortali B3QQU3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 517417.Cpar_0286.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACF10713 ; ACF10713 ; Cpar_0286 .
GeneIDi 6419199.
KEGGi cpc:Cpar_0286.
PATRICi 21363799. VBIChlPar72705_0284.

Phylogenomic databases

eggNOGi COG0787.
HOGENOMi HOG000031444.
KOi K01775.
OMAi AEININN.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci CPAR517417:GH95-300-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NCIB 8327Imported.

Entry informationi

Entry nameiB3QQU3_CHLP8
AccessioniPrimary (citable) accession number: B3QQU3
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: October 29, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3