B3QQE3 (B3QQE3_CHLP8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lipid-A-disaccharide synthase EMBL ACF12146.1
EC=2.4.1.182 EMBL ACF12146.1

Gene names

Ordered Locus Names:

Cpar_1754

Organism

Chlorobaculum parvum (strain NCIB 8327) (Chlorobium vibrioforme subsp. thiosulfatophilum (strain DSM 263 / NCIB 8327)) [Complete proteome] [HAMAP]

Taxonomic identifier

517417 [NCBI]

Taxonomic lineage

Bacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobaculum

Protein attributes

Sequence length	388 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 EMBL ACF12146.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B3QQE3 [UniParc]. Last modified September 2, 2008. Version 1. Checksum: 01CB9C5D4936EA5C	FASTA	388	43,501
	10 20 30 40 50 60 MMQFQQPTCG KTLFVLAGEV SGDLHAAGPV RMLLEQAPDT KVFGVGGRKL AELGAELLYT 70 80 90 100 110 120 TDEMSIMGFV EVLKQAPFLR KVIRELKAAI VREKPDAALL VDYPGMNLHL AAFLKKQGIP 130 140 150 160 170 180 VIYYISPQVW AWKERRVEKI RAYVDRLLVI FNFEVEFFRR HGIEAEFVGN PVVEELAEME 190 200 210 220 230 240 FPPKPQFLEK MGIDPDARII GLLPGSRRQE IEKIFPEMLG AAKLIQEKAK TVFLLGKSSH 250 260 270 280 290 300 IDPALYERHI RDAGVEPFDC TSYEVMQYSD LELVTSGTAT LESLCFAVPM VVLYKTSPLN 310 320 330 340 350 360 YFIGKRLVKL NNIALANIVS CGLLSEKQAV PELIQHEANA ENISRKALDI LCNEPVASAM 370 380 RRELQEARAR LSSDSPSRHV AAVLLEYL

References

[1]

"Complete sequence of Chlorobaculum parvum NCIB 8327." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Zhao F., Li T., Liu Z. , Overmann J., Bryant D.A., Richardson P. Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NCIB 8327.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001099 Genomic DNA. Translation: ACF12146.1.
RefSeq	YP_001999346.1. NC_011027.1.
3D structure databases
ProteinModelPortal	B3QQE3.
ModBase	Search...
Protein-protein interaction databases
STRING	B3QQE3.
Protein family/group databases
CAZy	GT19. Glycosyltransferase Family 19.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6420697.
GenomeReviews	Gene locus Cpar_1754 in contig CP001099_GR.
KEGG	cpc:Cpar_1754.
PATRIC	21366809. VBIChlPar72705_1756.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG584837.
OMA	PDFNLGL.
ProtClustDB	CLSK637261.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B3QQE3_CHLP8

Accession

Primary (citable) accession number: B3QQE3

Entry history

Integrated into UniProtKB/TrEMBL:	September 2, 2008
Last sequence update:	September 2, 2008
Last modified:	December 14, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)