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B3QQ94 (B3QQ94_CHLP8) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Non-canonical purine NTP pyrophosphatase HAMAP MF_01405
EC=3.6.1.19 HAMAP MF_01405
Alternative name(s):
Non-standard purine NTP pyrophosphatase HAMAP MF_01405
Nucleoside-triphosphate diphosphatase HAMAP MF_01405
Nucleoside-triphosphate pyrophosphatase HAMAP MF_01405
Gene names
Ordered Locus Names:Cpar_1705
OrganismChlorobaculum parvum (strain NCIB 8327) (Chlorobium vibrioforme subsp. thiosulfatophilum (strain DSM 263 / NCIB 8327)) [Complete proteome] [HAMAP]
Taxonomic identifier517417 [NCBI]
Taxonomic lineageBacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobaculum

Protein attributes

Sequence length223 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP/dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions By similarity. HAMAP MF_01405

Catalytic activity

A nucleoside triphosphate + H2O = a nucleotide + diphosphate. HAMAP MF_01405 SAAS SAAS020922

Cofactor

Binds 1 divalent metal cation ion per subunit; can use either magnesium or manganese By similarity. HAMAP MF_01405 SAAS SAAS020922

Subunit structure

Homodimer By similarity. HAMAP MF_01405 SAAS SAAS020922

Sequence similarities

Belongs to the HAM1 NTPase family. HAMAP MF_01405 RuleBase RU003781

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region12 – 176Substrate binding By similarity HAMAP MF_01405
Region81 – 822Substrate binding By similarity HAMAP MF_01405

Sites

Metal binding471Magnesium or manganese By similarity HAMAP MF_01405
Metal binding811Magnesium or manganese By similarity HAMAP MF_01405
Binding site1771Substrate By similarity HAMAP MF_01405
Binding site1971Substrate By similarity HAMAP MF_01405
Binding site2031Substrate By similarity HAMAP MF_01405

Sequences

Sequence LengthMass (Da)Tools
B3QQ94 [UniParc].

Last modified September 2, 2008. Version 1.
Checksum: AF290CAF17236E37

FASTA22324,275
        10         20         30         40         50         60 
MSTETIDIVL ATGNRDKVRE LKPVLEGIHP ALRVRALFEL GLEADVEETE TTLEDNARLK 

        70         80         90        100        110        120 
ADAIFELVRS QLNHFIALAD DTGLEVDALN GEPGVYSARF APMPPGQSPT YADNVRHLLD 

       130        140        150        160        170        180 
RMTGKTDRSA RFRTVIAMKG LLPSAADNDV TIEETVEGSV EGVITETTIG EGGFGYDPIF 

       190        200        210        220 
MPAGTGKTFA QLTIDEKNAI SHRGRAVQAA VRRIRQLLEQ CGL

« Hide

References

[1]"Complete sequence of Chlorobaculum parvum NCIB 8327."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Zhao F., Li T., Liu Z. expand/collapse author list , Overmann J., Bryant D.A., Richardson P.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NCIB 8327.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001099 Genomic DNA. Translation: ACF12097.1.
RefSeqYP_001999297.1. NC_011027.1.

3D structure databases

ProteinModelPortalB3QQ94.
ModBaseSearch...

Protein-protein interaction databases

STRINGB3QQ94.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6420646.
GenomeReviewsGene locus Cpar_1705 in contig CP001099_GR.
KEGGcpc:Cpar_1705.
PATRIC21366705. VBIChlPar72705_1706.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG697237.
OMAYSKRYDQ.
ProtClustDBPRK14826.

Family and domain databases

HAMAPMF_01405. Non_canon_purine_NTPase.
[Tree]
InterProIPR002637. Ham1p-like.
IPR020922. Nucleoside-triphosphatase.
[Graphical view]
KOK02428.
PANTHERPTHR11067. Ham1p_like. 1 hit.
PfamPF01725. Ham1p_like. 1 hit.
[Graphical view]
TIGRFAMsTIGR00042. TIGR00042. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB3QQ94_CHLP8
AccessionPrimary (citable) accession number: B3QQ94
Entry history
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: December 14, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info