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B3QQ86 (B3QQ86_CHLP8) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
1-deoxy-D-xylulose-5-phosphate synthase HAMAP MF_00315
EC=2.2.1.7 HAMAP MF_00315
Alternative name(s):
1-deoxyxylulose-5-phosphate synthase HAMAP MF_00315
Gene names
Name:dxs HAMAP MF_00315
Ordered Locus Names:Cpar_1696
OrganismChlorobaculum parvum (strain NCIB 8327) (Chlorobium vibrioforme subsp. thiosulfatophilum (strain DSM 263 / NCIB 8327)) [Complete proteome] [HAMAP]
Taxonomic identifier517417 [NCBI]
Taxonomic lineageBacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobaculum

Protein attributes

Sequence length642 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) By similarity. HAMAP MF_00315 SAAS SAAS005477

Catalytic activity

Pyruvate + D-glyceraldehyde 3-phosphate = 1-deoxy-D-xylulose 5-phosphate + CO2. HAMAP MF_00315 SAAS SAAS005477

Cofactor

Binds 1 thiamine pyrophosphate per subunit By similarity. HAMAP MF_00315 SAAS SAAS005477

Pathway

Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5-phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1. HAMAP MF_00315 SAAS SAAS005477

Subunit structure

Homodimer By similarity. HAMAP MF_00315 SAAS SAAS005477

Sequence similarities

Belongs to the transketolase family. DXPS subfamily. HAMAP MF_00315

Sequences

Sequence LengthMass (Da)Tools
B3QQ86 [UniParc].

Last modified September 2, 2008. Version 1.
Checksum: C2BEB1C9E1C59A7D

FASTA64269,524
        10         20         30         40         50         60 
MTEALSSPVS QGYSLLSTIH DPADLKKLSI SQLEQVAAEC RRKVIELVSQ HGGHFASSLG 

        70         80         90        100        110        120 
VVELTVALHH VYQSPTDRFI WDVGHQAYVH KMLTGRLEQM DTNRRYNGLA GFPKRSESAH 

       130        140        150        160        170        180 
DAFDTGHAST SISAAAGMAV ARDLAGRSEK VVAIIGDGSL TGGMAFEAMN HLGDVKSDVL 

       190        200        210        220        230        240 
VILNDNQMAI SPSTGGLNNY LVNLPLNKTY NKLRKFVWDS ISLMHNDIGE TAKTAVHRLE 

       250        260        270        280        290        300 
DGIKAAFTPG AYFEALGFRY FGPIDGHNME QLTKALSEMR SLPHPKLLHV ITKKGKGFKP 

       310        320        330        340        350        360 
AEENQPKWHA SAGGFDIETG ANLKAPGKPA KPKYQEVFGE ALVELALKDQ TITAITAAMP 

       370        380        390        400        410        420 
SGTSLDLFQQ AIPSRFFDVG IAEQHAVTFC AGLALGGFKP VCAIYSTFLQ RGYDQLIHDV 

       430        440        450        460        470        480 
ALQNLHVVFA IDRAGLVGED GPTHHGAFDL SYLNAVPNLT IMAPGDEQEL RDMLYTALYE 

       490        500        510        520        530        540 
VKGPVAIRYP RGTGTGATLH KEFTPIPVGK GRVLREGDTV ALLGIGSMSQ RALETAELLE 

       550        560        570        580        590        600 
KAGLNPLVCD MRFLKPLDTE MIDMAAAKCK HIVTIEENSI IGGFGSSVTS YLSHAHPGMK 

       610        620        630        640 
SISFGLPDDF VTHGSMQELY KEVGLDAETL AEKIQEFCKV EA

« Hide

References

[1]"Complete sequence of Chlorobaculum parvum NCIB 8327."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Zhao F., Li T., Liu Z. expand/collapse author list , Overmann J., Bryant D.A., Richardson P.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NCIB 8327.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001099 Genomic DNA. Translation: ACF12089.1.
RefSeqYP_001999289.1. NC_011027.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB3QQ86.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6420637.
GenomeReviewsGene locus Cpar_1696 in contig CP001099_GR.
KEGGcpc:Cpar_1696.
PATRIC21366689. VBIChlPar72705_1698.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG571647.
OMATRSYTQY.
ProtClustDBPRK05444.

Family and domain databases

HAMAPMF_00315. DXP_synth.
[Tree]
InterProIPR005477. Dxylulose-5-P_synthase.
IPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR015941. Transketolase-like_C.
IPR005475. Transketolase-like_Pyr-bd.
IPR020826. Transketolase_BS.
IPR005476. Transketolase_C.
IPR005474. Transketolase_N.
[Graphical view]
Gene3DG3DSA:3.40.50.920. Transketo_C_like. 1 hit.
KOK01662.
PfamPF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
PF00456. Transketolase_N. 1 hit.
[Graphical view]
SMARTSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMSSF52922. Transketo_C_like. 1 hit.
TIGRFAMsTIGR00204. Dxs. 1 hit.
PROSITEPS00801. TRANSKETOLASE_1. 1 hit.
PS00802. TRANSKETOLASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB3QQ86_CHLP8
AccessionPrimary (citable) accession number: B3QQ86
Entry history
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: December 14, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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