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Protein

S-adenosylmethionine:tRNA ribosyltransferase-isomerase

Gene

queA

Organism
Chlorobaculum parvum (strain NCIB 8327) (Chlorobium vibrioforme subsp. thiosulfatophilum (strain DSM 263 / NCIB 8327))
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + 7-aminomethyl-7-carbaguanosine(34) in tRNA = L-methionine + adenine + epoxyqueuosine(34) in tRNA.UniRule annotation

Pathwayi: tRNA-queuosine biosynthesis

This protein is involved in the pathway tRNA-queuosine biosynthesis, which is part of tRNA modification.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway tRNA-queuosine biosynthesis and in tRNA modification.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processQueuosine biosynthesis
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciCPAR517417:G1GC8-1475-MONOMER
UniPathwayiUPA00392

Names & Taxonomyi

Protein namesi
Recommended name:
S-adenosylmethionine:tRNA ribosyltransferase-isomeraseUniRule annotation (EC:2.4.99.17UniRule annotation)
Alternative name(s):
Queuosine biosynthesis protein QueAUniRule annotation
Gene namesi
Name:queAUniRule annotation
Ordered Locus Names:Cpar_1439
OrganismiChlorobaculum parvum (strain NCIB 8327) (Chlorobium vibrioforme subsp. thiosulfatophilum (strain DSM 263 / NCIB 8327))
Taxonomic identifieri517417 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobaculum
Proteomesi
  • UP000008811 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000947631 – 340S-adenosylmethionine:tRNA ribosyltransferase-isomeraseAdd BLAST340

Proteomic databases

PRIDEiB3QPI5

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi517417.Cpar_1439

Family & Domainsi

Sequence similaritiesi

Belongs to the QueA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105E2N Bacteria
COG0809 LUCA
HOGENOMiHOG000004401
KOiK07568
OMAiYSYGDGM
OrthoDBiPOG091H00ZG

Family and domain databases

HAMAPiMF_00113 QueA, 1 hit
InterProiView protein in InterPro
IPR003699 QueA
IPR036100 QueA_sf
PANTHERiPTHR30307 PTHR30307, 1 hit
PfamiView protein in Pfam
PF02547 Queuosine_synth, 1 hit
SUPFAMiSSF111337 SSF111337, 1 hit
TIGRFAMsiTIGR00113 queA, 1 hit

Sequencei

Sequence statusi: Complete.

B3QPI5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRVEEFDYTL PEERIATYPP AERGSTRLIV LDRAADSITH SVYASLHERL
60 70 80 90 100
RPGDLLVLNN SKVIRARLIA NKPTGGRIEL MLLEKHEGVQ NLALYRGRLK
110 120 130 140 150
VGDRLLAHGA ELTVEALPDH GVARLSCDTA NLTELFEAHG SVPIPPYLKR
160 170 180 190 200
DAEEVDRERY QTVFAELPGS VAAPTASLNL TDELLEKIKA KGVDVVHITL
210 220 230 240 250
HVGLGTFLPI RSETFEEHVM HREFYNIPES SAHKIGEAKA RGGRVVAVGT
260 270 280 290 300
TVTRALEHAA PRLLDSDFSQ EVSGEADIFI YPGYEFRIID ALLTNFHAPR
310 320 330 340
STVLMLTAAF AGKELLRRAY QEALERDYRF LSYGDSMFIS
Length:340
Mass (Da):37,913
Last modified:September 2, 2008 - v1
Checksum:i0D3BEAFE3327EF18
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001099 Genomic DNA Translation: ACF11838.1
RefSeqiWP_012502671.1, NC_011027.1

Genome annotation databases

EnsemblBacteriaiACF11838; ACF11838; Cpar_1439
KEGGicpc:Cpar_1439

Similar proteinsi

Entry informationi

Entry nameiQUEA_CHLP8
AccessioniPrimary (citable) accession number: B3QPI5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 2, 2008
Last modified: May 23, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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