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Protein

Argininosuccinate lyase

Gene

argH

Organism
Chlorobaculum parvum (strain NCIB 8327) (Chlorobium vibrioforme subsp. thiosulfatophilum (strain DSM 263 / NCIB 8327))
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

2-(N(omega)-L-arginino)succinate = fumarate + L-arginine.UniRule annotation

Pathwayi: L-arginine biosynthesis

This protein is involved in step 3 of the subpathway that synthesizes L-arginine from L-ornithine and carbamoyl phosphate.UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Argininosuccinate synthase (argG)
  3. Argininosuccinate lyase (argH)
This subpathway is part of the pathway L-arginine biosynthesis, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes L-arginine from L-ornithine and carbamoyl phosphate, the pathway L-arginine biosynthesis and in Amino-acid biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase
Biological processAmino-acid biosynthesis, Arginine biosynthesis

Enzyme and pathway databases

BioCyciCPAR517417:G1GC8-1016-MONOMER.
UniPathwayiUPA00068; UER00114.

Names & Taxonomyi

Protein namesi
Recommended name:
Argininosuccinate lyaseUniRule annotation (EC:4.3.2.1UniRule annotation)
Short name:
ASALUniRule annotation
Alternative name(s):
ArginosuccinaseUniRule annotation
Gene namesi
Name:argHUniRule annotation
Ordered Locus Names:Cpar_0985
OrganismiChlorobaculum parvum (strain NCIB 8327) (Chlorobium vibrioforme subsp. thiosulfatophilum (strain DSM 263 / NCIB 8327))
Taxonomic identifieri517417 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobaculum
Proteomesi
  • UP000008811 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000890731 – 463Argininosuccinate lyaseAdd BLAST463

Interactioni

Protein-protein interaction databases

STRINGi517417.Cpar_0985.

Structurei

3D structure databases

ProteinModelPortaliB3QN90.
SMRiB3QN90.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CH7. Bacteria.
COG0165. LUCA.
HOGENOMiHOG000242744.
KOiK01755.
OMAiSIMPHKK.
OrthoDBiPOG091H026A.

Family and domain databases

CDDicd01359. Argininosuccinate_lyase. 1 hit.
Gene3Di1.10.275.10. 2 hits.
HAMAPiMF_00006. Arg_succ_lyase. 1 hit.
InterProiView protein in InterPro
IPR029419. Arg_succ_lyase_C.
IPR009049. Argininosuccinate_lyase.
IPR024083. Fumarase/histidase_N.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
PANTHERiPTHR43814. PTHR43814. 1 hit.
PfamiView protein in Pfam
PF14698. ASL_C2. 1 hit.
PF00206. Lyase_1. 1 hit.
PRINTSiPR00149. FUMRATELYASE.
SUPFAMiSSF48557. SSF48557. 1 hit.
TIGRFAMsiTIGR00838. argH. 1 hit.
PROSITEiView protein in PROSITE
PS00163. FUMARATE_LYASES. 1 hit.

Sequencei

Sequence statusi: Complete.

B3QN90-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDQSKQKEL LWQSRFSEPF DREALQFSSS VHVDGLLYRE DIQGSIAHAT
60 70 80 90 100
MLGEEGIISA GESEQIVEGL KAVEKEIESG ELVPVWEDED IHTVIENRLK
110 120 130 140 150
ELIGPAAGKL HSGRSRNDQV ATDTRLYLRR NIDRLVGLLE AMQSTLLDKA
160 170 180 190 200
ERYKSTIMFG YTHLQRAQPM SAGHYYMAWH SMFGRDAERL ADLRKRANIS
210 220 230 240 250
PLGAAAFAGS TLPLNPARSA ELLEFDGVFA NSIDAVSDRD LVIEFVSACS
260 270 280 290 300
MIMMHLSRFS EDVILWTSAE FNYLSISDAF ATGSSIMPQK KNADIAELVR
310 320 330 340 350
GKTGRVYGNL MNLLTIMKGL PLSYNRDMQE DKPPLFDTAE TTASSLSVFR
360 370 380 390 400
RMIEKTWLNE ERLAKLTAED LSLATEIAEY LVKKQIPFRD AHRITGKIVA
410 420 430 440 450
YAIEKSKTLP TISLDEYRTF SESFDEGIYD DLKPDASVNS KKTAGSCSFK
460
SVEEQIARAR KNS
Length:463
Mass (Da):51,895
Last modified:September 2, 2008 - v1
Checksum:i7581FC0BDAACBE1A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001099 Genomic DNA. Translation: ACF11393.1.
RefSeqiWP_012502226.1. NC_011027.1.

Genome annotation databases

EnsemblBacteriaiACF11393; ACF11393; Cpar_0985.
KEGGicpc:Cpar_0985.

Similar proteinsi

Entry informationi

Entry nameiARLY_CHLP8
AccessioniPrimary (citable) accession number: B3QN90
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 2, 2008
Last modified: February 28, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome