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Protein

Putative thymidine phosphorylase

Gene

Rpal_4625

Organism
Rhodopseudomonas palustris (strain TIE-1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.UniRule annotation

GO - Molecular functioni

  1. phosphorylase activity Source: InterPro
  2. thymidine phosphorylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. pyrimidine nucleobase metabolic process Source: InterPro
  2. pyrimidine nucleoside metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Enzyme and pathway databases

BioCyciRPAL395960:GHPC-4670-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative thymidine phosphorylaseUniRule annotation (EC:2.4.2.4UniRule annotation)
Alternative name(s):
TdRPaseUniRule annotation
Gene namesi
Ordered Locus Names:Rpal_4625
OrganismiRhodopseudomonas palustris (strain TIE-1)
Taxonomic identifieri395960 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
ProteomesiUP000001725: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 514514Putative thymidine phosphorylasePRO_1000132353Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi395960.Rpal_4625.

Structurei

3D structure databases

ProteinModelPortaliB3QKL9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0213.
HOGENOMiHOG000252767.
KOiK00758.
OMAiMAVLGNE.
OrthoDBiEOG61ZTGG.

Family and domain databases

Gene3Di3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPiMF_00703. Thymid_phosp_2.
InterProiIPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view]
PANTHERiPTHR10515. PTHR10515. 1 hit.
PfamiPF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view]
PIRSFiPIRSF000478. TP_PyNP. 1 hit.
SMARTiSM00941. PYNP_C. 1 hit.
[Graphical view]
SUPFAMiSSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsiTIGR02645. ARCH_P_rylase. 1 hit.
PROSITEiPS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3QKL9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNAPDLTRPP LTIRRISLDT GRENVAVISR RSRALRPEVF RGFSRVELRI
60 70 80 90 100
NSKVLLATLM ITDDDAMIGP DEVGLSEPAF RRFNEPVGSA VSVTPARSPA
110 120 130 140 150
SLDAVRAKIQ GHTLSAAEIT AIVDDLAHFR YSDMEIAAFL ISAARFTTTD
160 170 180 190 200
ELLALVGAMA SVGTKLTWDT PIVVDKHCIG GIPGNRTTMI VVPIVAAHGL
210 220 230 240 250
MIPKTSSRAI TSPAGTADTM ELLARVDLDV EQMKQVVHAC GGCLVWGGHV
260 270 280 290 300
NLSPADDILI SVERPLSLDT PEQMVASIMS KKLAAGSTRL LIDFPVGPSA
310 320 330 340 350
KVTSANEAMR LRKLFEFVGD HFGISVEVVT TDGRQPIGRG IGPVLEARDV
360 370 380 390 400
MAVLGNKPGA PADLREKSLR LAAHLLEYDP KLRGGTGYAR AKELLDSGAA
410 420 430 440 450
LKKMQQIIDA QGPSPCPAEL GSYAADVLAA ADGVVNGIDC LRINRLARSA
460 470 480 490 500
GAPVAKGAGI DLFKKIGDRV EKGEPLYRVY ASDRSEFDLA LAAAQAESGF
510
AINHHTPADV DLVS
Length:514
Mass (Da):54,652
Last modified:September 2, 2008 - v1
Checksum:i245697DBC324B925
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001096 Genomic DNA. Translation: ACF03116.1.
RefSeqiYP_001993591.1. NC_011004.1.

Genome annotation databases

EnsemblBacteriaiACF03116; ACF03116; Rpal_4625.
GeneIDi6412311.
KEGGirpt:Rpal_4625.
PATRICi23313781. VBIRhoPal88240_4678.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001096 Genomic DNA. Translation: ACF03116.1.
RefSeqiYP_001993591.1. NC_011004.1.

3D structure databases

ProteinModelPortaliB3QKL9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi395960.Rpal_4625.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACF03116; ACF03116; Rpal_4625.
GeneIDi6412311.
KEGGirpt:Rpal_4625.
PATRICi23313781. VBIRhoPal88240_4678.

Phylogenomic databases

eggNOGiCOG0213.
HOGENOMiHOG000252767.
KOiK00758.
OMAiMAVLGNE.
OrthoDBiEOG61ZTGG.

Enzyme and pathway databases

BioCyciRPAL395960:GHPC-4670-MONOMER.

Family and domain databases

Gene3Di3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPiMF_00703. Thymid_phosp_2.
InterProiIPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view]
PANTHERiPTHR10515. PTHR10515. 1 hit.
PfamiPF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view]
PIRSFiPIRSF000478. TP_PyNP. 1 hit.
SMARTiSM00941. PYNP_C. 1 hit.
[Graphical view]
SUPFAMiSSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsiTIGR02645. ARCH_P_rylase. 1 hit.
PROSITEiPS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TIE-1.

Entry informationi

Entry nameiTYPH_RHOPT
AccessioniPrimary (citable) accession number: B3QKL9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 2, 2008
Last modified: February 4, 2015
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.