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B3QKL9

- TYPH_RHOPT

UniProt

B3QKL9 - TYPH_RHOPT

Protein

Putative thymidine phosphorylase

Gene

Rpal_4625

Organism
Rhodopseudomonas palustris (strain TIE-1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 41 (01 Oct 2014)
      Sequence version 1 (02 Sep 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.UniRule annotation

    GO - Molecular functioni

    1. phosphorylase activity Source: InterPro
    2. thymidine phosphorylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. pyrimidine nucleobase metabolic process Source: InterPro
    2. pyrimidine nucleoside metabolic process Source: InterPro

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Enzyme and pathway databases

    BioCyciRPAL395960:GHPC-4670-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative thymidine phosphorylaseUniRule annotation (EC:2.4.2.4UniRule annotation)
    Alternative name(s):
    TdRPaseUniRule annotation
    Gene namesi
    Ordered Locus Names:Rpal_4625
    OrganismiRhodopseudomonas palustris (strain TIE-1)
    Taxonomic identifieri395960 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
    ProteomesiUP000001725: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 514514Putative thymidine phosphorylasePRO_1000132353Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi395960.Rpal_4625.

    Structurei

    3D structure databases

    ProteinModelPortaliB3QKL9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0213.
    HOGENOMiHOG000252767.
    KOiK00758.
    OMAiLEWAFDE.
    OrthoDBiEOG61ZTGG.

    Family and domain databases

    Gene3Di3.40.1030.10. 1 hit.
    3.90.1170.30. 1 hit.
    HAMAPiMF_00703. Thymid_phosp_2.
    InterProiIPR000312. Glycosyl_Trfase_fam3.
    IPR017459. Glycosyl_Trfase_fam3_N_dom.
    IPR013102. PYNP_C.
    IPR000053. Pyrmidine_PPase.
    IPR017872. Pyrmidine_PPase_CS.
    IPR028579. Thym_Pase_Put.
    IPR013466. Thymidine/AMP_Pase.
    [Graphical view]
    PANTHERiPTHR10515. PTHR10515. 1 hit.
    PfamiPF02885. Glycos_trans_3N. 1 hit.
    PF00591. Glycos_transf_3. 1 hit.
    PF07831. PYNP_C. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000478. TP_PyNP. 1 hit.
    SMARTiSM00941. PYNP_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF47648. SSF47648. 1 hit.
    SSF52418. SSF52418. 1 hit.
    SSF54680. SSF54680. 1 hit.
    TIGRFAMsiTIGR02645. ARCH_P_rylase. 1 hit.
    PROSITEiPS00647. THYMID_PHOSPHORYLASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B3QKL9-1 [UniParc]FASTAAdd to Basket

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    MNAPDLTRPP LTIRRISLDT GRENVAVISR RSRALRPEVF RGFSRVELRI    50
    NSKVLLATLM ITDDDAMIGP DEVGLSEPAF RRFNEPVGSA VSVTPARSPA 100
    SLDAVRAKIQ GHTLSAAEIT AIVDDLAHFR YSDMEIAAFL ISAARFTTTD 150
    ELLALVGAMA SVGTKLTWDT PIVVDKHCIG GIPGNRTTMI VVPIVAAHGL 200
    MIPKTSSRAI TSPAGTADTM ELLARVDLDV EQMKQVVHAC GGCLVWGGHV 250
    NLSPADDILI SVERPLSLDT PEQMVASIMS KKLAAGSTRL LIDFPVGPSA 300
    KVTSANEAMR LRKLFEFVGD HFGISVEVVT TDGRQPIGRG IGPVLEARDV 350
    MAVLGNKPGA PADLREKSLR LAAHLLEYDP KLRGGTGYAR AKELLDSGAA 400
    LKKMQQIIDA QGPSPCPAEL GSYAADVLAA ADGVVNGIDC LRINRLARSA 450
    GAPVAKGAGI DLFKKIGDRV EKGEPLYRVY ASDRSEFDLA LAAAQAESGF 500
    AINHHTPADV DLVS 514
    Length:514
    Mass (Da):54,652
    Last modified:September 2, 2008 - v1
    Checksum:i245697DBC324B925
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001096 Genomic DNA. Translation: ACF03116.1.
    RefSeqiYP_001993591.1. NC_011004.1.

    Genome annotation databases

    EnsemblBacteriaiACF03116; ACF03116; Rpal_4625.
    GeneIDi6412311.
    KEGGirpt:Rpal_4625.
    PATRICi23313781. VBIRhoPal88240_4678.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001096 Genomic DNA. Translation: ACF03116.1 .
    RefSeqi YP_001993591.1. NC_011004.1.

    3D structure databases

    ProteinModelPortali B3QKL9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 395960.Rpal_4625.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACF03116 ; ACF03116 ; Rpal_4625 .
    GeneIDi 6412311.
    KEGGi rpt:Rpal_4625.
    PATRICi 23313781. VBIRhoPal88240_4678.

    Phylogenomic databases

    eggNOGi COG0213.
    HOGENOMi HOG000252767.
    KOi K00758.
    OMAi LEWAFDE.
    OrthoDBi EOG61ZTGG.

    Enzyme and pathway databases

    BioCyci RPAL395960:GHPC-4670-MONOMER.

    Family and domain databases

    Gene3Di 3.40.1030.10. 1 hit.
    3.90.1170.30. 1 hit.
    HAMAPi MF_00703. Thymid_phosp_2.
    InterProi IPR000312. Glycosyl_Trfase_fam3.
    IPR017459. Glycosyl_Trfase_fam3_N_dom.
    IPR013102. PYNP_C.
    IPR000053. Pyrmidine_PPase.
    IPR017872. Pyrmidine_PPase_CS.
    IPR028579. Thym_Pase_Put.
    IPR013466. Thymidine/AMP_Pase.
    [Graphical view ]
    PANTHERi PTHR10515. PTHR10515. 1 hit.
    Pfami PF02885. Glycos_trans_3N. 1 hit.
    PF00591. Glycos_transf_3. 1 hit.
    PF07831. PYNP_C. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000478. TP_PyNP. 1 hit.
    SMARTi SM00941. PYNP_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47648. SSF47648. 1 hit.
    SSF52418. SSF52418. 1 hit.
    SSF54680. SSF54680. 1 hit.
    TIGRFAMsi TIGR02645. ARCH_P_rylase. 1 hit.
    PROSITEi PS00647. THYMID_PHOSPHORYLASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: TIE-1.

    Entry informationi

    Entry nameiTYPH_RHOPT
    AccessioniPrimary (citable) accession number: B3QKL9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: September 2, 2008
    Last modified: October 1, 2014
    This is version 41 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3