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Protein

S-adenosylmethionine:tRNA ribosyltransferase-isomerase

Gene

queA

Organism
Rhodopseudomonas palustris (strain TIE-1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + 7-aminomethyl-7-carbaguanosine(34) in tRNA = L-methionine + adenine + epoxyqueuosine(34) in tRNA.UniRule annotation

Pathwayi: tRNA-queuosine biosynthesis

This protein is involved in the pathway tRNA-queuosine biosynthesis, which is part of tRNA modification.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway tRNA-queuosine biosynthesis and in tRNA modification.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processQueuosine biosynthesis
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciRPAL395960:RPAL_RS14245-MONOMER
UniPathwayiUPA00392

Names & Taxonomyi

Protein namesi
Recommended name:
S-adenosylmethionine:tRNA ribosyltransferase-isomeraseUniRule annotation (EC:2.4.99.17UniRule annotation)
Alternative name(s):
Queuosine biosynthesis protein QueAUniRule annotation
Gene namesi
Name:queAUniRule annotation
Ordered Locus Names:Rpal_2875
OrganismiRhodopseudomonas palustris (strain TIE-1)
Taxonomic identifieri395960 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
Proteomesi
  • UP000001725 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000948081 – 360S-adenosylmethionine:tRNA ribosyltransferase-isomeraseAdd BLAST360

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB3QIN0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the QueA family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000004401
KOiK07568
OMAiYSYGDGM
OrthoDBiPOG091H00ZG

Family and domain databases

HAMAPiMF_00113 QueA, 1 hit
InterProiView protein in InterPro
IPR003699 QueA
IPR036100 QueA_sf
PANTHERiPTHR30307 PTHR30307, 1 hit
PfamiView protein in Pfam
PF02547 Queuosine_synth, 1 hit
SUPFAMiSSF111337 SSF111337, 1 hit
TIGRFAMsiTIGR00113 queA, 1 hit

Sequencei

Sequence statusi: Complete.

B3QIN0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRTELFDFDL PTQNIALRPV SPRDAARMLV VRPSVPLEDR IVRDLPALLA
60 70 80 90 100
PGDQLVVNDT RVIAAQLTGR RIGRGLEPKI EATLIKRLDG ARWQALVKPA
110 120 130 140 150
KKLLPGDVVR FGHDGRVCLL GHLDATVEAK GDAGEVTLAF SFHGPVLDQA
160 170 180 190 200
IAEVGATPLP PYIASKRAPD AQDIADYQTM FASNEGAVAA PTAGLHFTAE
210 220 230 240 250
LETALAARGV GLHRITLHVG AGTFLPVKAE DTSEHRMHAE WGTISSGTAE
260 270 280 290 300
ALNAARAAGG RIVAVGTTSL RLLESAARDD GRIAPFADET SIFITPGYRF
310 320 330 340 350
RAVDMLMTNF HLPRSTLFML VSAFCGLDTM QAAYAHAIRT GYRFYSYGDA
360
SLLFRNDITP
Length:360
Mass (Da):38,804
Last modified:September 2, 2008 - v1
Checksum:iC0E9F16CF4CF72A5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001096 Genomic DNA Translation: ACF01383.1
RefSeqiWP_012496047.1, NC_011004.1

Genome annotation databases

EnsemblBacteriaiACF01383; ACF01383; Rpal_2875
KEGGirpt:Rpal_2875

Similar proteinsi

Entry informationi

Entry nameiQUEA_RHOPT
AccessioniPrimary (citable) accession number: B3QIN0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 2, 2008
Last modified: June 20, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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