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B3QHB7 (B3QHB7_RHOPT) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1 HAMAP MF_00191
EC=1.17.1.2 HAMAP MF_00191
Gene names
Name:ispH1 HAMAP MF_00191
Ordered Locus Names:Rpal_4255
OrganismRhodopseudomonas palustris (strain TIE-1) [Complete proteome] [HAMAP]
Taxonomic identifier395960 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Rhodopseudomonas

Protein attributes

Sequence length314 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) By similarity. HAMAP MF_00191 SAAS SAAS003451

Catalytic activity

Dimethylallyl diphosphate + NAD(P)+ + H2O = (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H. HAMAP MF_00191 SAAS SAAS003451

Isopentenyl diphosphate + NAD(P)+ + H2O = (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H. HAMAP MF_00191 SAAS SAAS003451

Cofactor

Binds 1 3Fe-4S cluster By similarity. HAMAP MF_00191

Pathway

Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from (2E)-4-hydroxy-3-methylbutenyl diphosphate: step 1/1. HAMAP MF_00191 SAAS SAAS003451

Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 6/6. HAMAP MF_00191 SAAS SAAS003451

Sequence similarities

Belongs to the IspH family. HAMAP MF_00191

Sequences

Sequence LengthMass (Da)Tools
B3QHB7 [UniParc].

Last modified September 2, 2008. Version 1.
Checksum: 9EBA6301DD10C35B

FASTA31433,815
        10         20         30         40         50         60 
MSEVRPLEVF LAQPRGFCAG VVRAIEIVER ALEKYGPPVY VRHEIVHNKY VVESLKAKGA 

        70         80         90        100        110        120 
IFVEELSEVP PKAVTVFSAH GVARSIEEEA AARDLPVLNA TCPLVTKVHN QGKRYTSKGR 

       130        140        150        160        170        180 
TLILIGHAGH PEVEGTMGQV PGPVLLVQNL DDVAALTLPP ETPVAYITQT TLSVDDTKDI 

       190        200        210        220        230        240 
IVALSKKFHD IEGPDTRDIC YATQNRQSAV RQMSKLVDLI LVVGANNSSN SNRLREIGTE 

       250        260        270        280        290        300 
AGIPSYLIAD GSELDPAWLD GKKAVGITAG ASAPEVLVDD VIEALRRIVP VTVSVLPGRE 

       310 
ENIEFVLPAE LATA

« Hide

References

[1]"Complete sequence of Rhodopseudomonas palustris TIE-1."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. expand/collapse author list , Emerson D., Newman D.K., Roden E., Richardson P.
Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: TIE-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001096 Genomic DNA. Translation: ACF02751.1.
RefSeqYP_001993226.1. NC_011004.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB3QHB7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6411939.
GenomeReviewsGene locus Rpal_4255 in contig CP001096_GR.
KEGGrpt:Rpal_4255.
PATRIC23313021. VBIRhoPal88240_4301.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG335228.
OMAHNQGKRY.
ProtClustDBPRK01045.

Family and domain databases

HAMAPMF_00191. IspH.
[Tree]
InterProIPR003451. LytB.
[Graphical view]
KOK03527.
PfamPF02401. LYTB. 1 hit.
[Graphical view]
TIGRFAMsTIGR00216. IspH_lytB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB3QHB7_RHOPT
AccessionPrimary (citable) accession number: B3QHB7
Entry history
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: December 14, 2011
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info