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B3QH48 (B3QH48_RHOPT) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length1053 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs By similarity. HAMAP-Rule MF_00970

Catalytic activity

Endonucleolytic cleavage of single-stranded RNA in A- and U-rich regions. HAMAP-Rule MF_00970

Cofactor

Binds 1 Mg2+ ion per subunit By similarity. HAMAP-Rule MF_00970

Binds 2 Zn2+ ions per homotetramer By similarity. HAMAP-Rule MF_00970

Subunit structure

Homotetramer formed by a dimer of dimers By similarity. HAMAP-Rule MF_00970

Subcellular location

Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side By similarity HAMAP-Rule MF_00970.

Sequence similarities

Belongs to the RNase E/G family. RNase E subfamily. HAMAP-Rule MF_00970

Contains 1 S1 motif domain. HAMAP-Rule MF_00970

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain40 – 11172S1 motif By similarity HAMAP-Rule MF_00970
Region645 – 6484Required for zinc-mediated homotetramerization and catalytic activity By similarity HAMAP-Rule MF_00970

Sites

Metal binding5441Magnesium; catalytic By similarity HAMAP-Rule MF_00970
Metal binding5871Magnesium; catalytic By similarity HAMAP-Rule MF_00970
Metal binding6451Zinc; shared with dimeric partner By similarity HAMAP-Rule MF_00970
Metal binding6481Zinc; shared with dimeric partner By similarity HAMAP-Rule MF_00970

Sequences

Sequence LengthMass (Da)Tools
B3QH48 [UniParc].

Last modified September 2, 2008. Version 1.
Checksum: 630391D431EEC8AE

FASTA1,053115,731
        10         20         30         40         50         60 
MANKMLIDAT HPEETRVVVV RGNRVEEFDF ETAQRKQLRG NIYLAKVTRV EPSLQAAFIE 

        70         80         90        100        110        120 
YGGNRHGFLA FSEIHPDYYQ IPVADRQALI EADERAHREA EEENEQRSSR RRSRHRSHRR 

       130        140        150        160        170        180 
RNNGERVQSE IVEAATDVAA EQPHEAADHH EAHEAGAHAE AERLMHELPE GETAEQHDAE 

       190        200        210        220        230        240 
YAADHEHTHV EAAPSEPQVS AAAEPVTIEQ PAAAEAPAPV EAPQAAASHD ETDAHDDDHG 

       250        260        270        280        290        300 
EDSANYAEDA PFPIDEHHEA EDEHEAHDDH VEGEHEVETD SDSDTEAEAE DDEEEDDEEE 

       310        320        330        340        350        360 
AEEDVVESVG GDDVLEEVPE RAFRPRRQYK IQEVIKRRQV MLVQVVKEER GNKGAALTTY 

       370        380        390        400        410        420 
LSLAGRYAVL MPNTARGGGI SRKITSAQDR SRLKEVVQDL DVPEGMGVIL RTAGASRTKP 

       430        440        450        460        470        480 
EIKRDFEYLI RMWETVRDVT LNSQAPKLVY EEGSLIKRSL RDLYNKEIDE VLVAGEAGYR 

       490        500        510        520        530        540 
EARDFMHMLM PSQVRAVKLY RDGQPLFSRM GVESQLDAMF SPTVQLRSGG YIVINQTEAL 

       550        560        570        580        590        600 
VSIDVNSGRS TREHHIEDTA LKTNMEAAEE VARQLRLRDL AGLIVIDFID MDEKRNNRAV 

       610        620        630        640        650        660 
ERKLSDCLRQ DRARIQVGRI SHFGLLEMSR QRIRASVLES STEPCPHCGG SGHVRSVSSV 

       670        680        690        700        710        720 
ALQLLRGLEE VLMKGATHNL IVRTRTDVAL YVLNHKRGHL RDLETGFRVS LSVLADPTVS 

       730        740        750        760        770        780 
GQQSFVIDRG EQVHTLETAK ALLAAQIAAS PAPLDEPEDD DGYDFEAEIE TDETVGLAED 

       790        800        810        820        830        840 
QGSEAGESES EGRKRRRRRR RRRSGEPREA AEAGAVGEDG EQPFVSEGVE QVGEADEGDE 

       850        860        870        880        890        900 
AGEDDSDAEA RADQGENGER RPRRRGRRGG RRRRGNAEAG ENEAGVVGSI SDELSPTDEA 

       910        920        930        940        950        960 
EAADAVADFD GGSPSVQPSF EPAAEAEQPH DAPPHDIVPS EPQHTAATAA PDTSDPSAED 

       970        980        990       1000       1010       1020 
DSAAKKAARR RSTVREKVSF GASAAASETT AEAAAEVQPE PTAQAEQPAT AAPAVEAPAA 

      1030       1040       1050 
EAAPQAAAQP AEEPSSAAPR RVGWWSRRFG GGN 

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References

[1]"Complete sequence of Rhodopseudomonas palustris TIE-1."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. expand/collapse author list , Emerson D., Newman D.K., Roden E., Richardson P.
Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: TIE-1 EMBL ACF01237.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001096 Genomic DNA. Translation: ACF01237.1.
RefSeqYP_001991712.1. NC_011004.1.

3D structure databases

ProteinModelPortalB3QH48.
SMRB3QH48. Positions 36-80.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING395960.Rpal_2728.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACF01237; ACF01237; Rpal_2728.
GeneID6410392.
KEGGrpt:Rpal_2728.
PATRIC23309912. VBIRhoPal88240_2766.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1530.
HOGENOMHOG000258026.
KOK08300.
OMAPFGLLEM.
OrthoDBEOG6PCPTH.

Enzyme and pathway databases

BioCycRPAL395960:GHPC-2750-MONOMER.

Family and domain databases

Gene3D2.40.50.140. 2 hits.
HAMAPMF_00970. RNase_E.
InterProIPR012340. NA-bd_OB-fold.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR019307. RNA-bd_AU-1/RNase_E/G.
IPR022967. RNA-binding_domain_S1.
IPR028878. RNase_E.
IPR004659. RNase_E/G.
[Graphical view]
PfamPF10150. RNase_E_G. 1 hit.
PF00575. S1. 1 hit.
[Graphical view]
SMARTSM00316. S1. 1 hit.
[Graphical view]
SUPFAMSSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00757. RNaseEG. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB3QH48_RHOPT
AccessionPrimary (citable) accession number: B3QH48
Entry history
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: June 11, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)