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B3QH48

- B3QH48_RHOPT

UniProt

B3QH48 - B3QH48_RHOPT

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Protein
Ribonuclease E
Gene
rne, Rpal_2728
Organism
Rhodopseudomonas palustris (strain TIE-1)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs By similarity.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of single-stranded RNA in A- and U-rich regions.UniRule annotation

Cofactori

Binds 1 Mg2+ ion per subunit By similarity.UniRule annotation
Binds 2 Zn2+ ions per homotetramer By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi544 – 5441Magnesium; catalytic By similarityUniRule annotation
Metal bindingi587 – 5871Magnesium; catalytic By similarityUniRule annotation
Metal bindingi645 – 6451Zinc; shared with dimeric partner By similarityUniRule annotation
Metal bindingi648 – 6481Zinc; shared with dimeric partner By similarityUniRule annotation

GO - Molecular functioni

  1. RNA binding Source: UniProtKB-HAMAP
  2. endoribonuclease activity Source: UniProtKB-HAMAP
  3. magnesium ion binding Source: UniProtKB-HAMAP
  4. ribonuclease E activity Source: InterPro
  5. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. mRNA catabolic process Source: UniProtKB-HAMAP
  2. rRNA processing Source: UniProtKB-HAMAP
  3. tRNA processing Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

EndonucleaseUniRule annotation, Hydrolase, Nuclease

Keywords - Biological processi

rRNA processingUniRule annotation, tRNA processingUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation, RNA-bindingUniRule annotation, ZincUniRule annotation

Enzyme and pathway databases

BioCyciRPAL395960:GHPC-2750-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease EUniRule annotation (EC:3.1.26.12UniRule annotation)
Short name:
RNase EUniRule annotation
Gene namesi
Name:rneUniRule annotation
Ordered Locus Names:Rpal_2728Imported
OrganismiRhodopseudomonas palustris (strain TIE-1)Imported
Taxonomic identifieri395960 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
ProteomesiUP000001725: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. cytoplasmic side of plasma membrane Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membraneUniRule annotation, Cell membrane, CytoplasmUniRule annotation, Membrane

Interactioni

Subunit structurei

Homotetramer formed by a dimer of dimers By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi395960.Rpal_2728.

Structurei

3D structure databases

ProteinModelPortaliB3QH48.
SMRiB3QH48. Positions 36-80.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini40 – 11172S1 motif By similarityUniRule annotation
Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni645 – 6484Required for zinc-mediated homotetramerization and catalytic activity By similarityUniRule annotation

Sequence similaritiesi

Belongs to the RNase E/G family. RNase E subfamily.UniRule annotation
Contains 1 S1 motif domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG1530.
HOGENOMiHOG000258026.
KOiK08300.
OMAiPFGLLEM.
OrthoDBiEOG6PCPTH.

Family and domain databases

Gene3Di2.40.50.140. 2 hits.
HAMAPiMF_00970. RNase_E.
InterProiIPR012340. NA-bd_OB-fold.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR019307. RNA-bd_AU-1/RNase_E/G.
IPR022967. RNA-binding_domain_S1.
IPR028878. RNase_E.
IPR004659. RNase_E/G.
[Graphical view]
PfamiPF10150. RNase_E_G. 1 hit.
PF00575. S1. 1 hit.
[Graphical view]
SMARTiSM00316. S1. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00757. RNaseEG. 1 hit.

Sequencei

Sequence statusi: Complete.

B3QH48-1 [UniParc]FASTAAdd to Basket

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MANKMLIDAT HPEETRVVVV RGNRVEEFDF ETAQRKQLRG NIYLAKVTRV     50
EPSLQAAFIE YGGNRHGFLA FSEIHPDYYQ IPVADRQALI EADERAHREA 100
EEENEQRSSR RRSRHRSHRR RNNGERVQSE IVEAATDVAA EQPHEAADHH 150
EAHEAGAHAE AERLMHELPE GETAEQHDAE YAADHEHTHV EAAPSEPQVS 200
AAAEPVTIEQ PAAAEAPAPV EAPQAAASHD ETDAHDDDHG EDSANYAEDA 250
PFPIDEHHEA EDEHEAHDDH VEGEHEVETD SDSDTEAEAE DDEEEDDEEE 300
AEEDVVESVG GDDVLEEVPE RAFRPRRQYK IQEVIKRRQV MLVQVVKEER 350
GNKGAALTTY LSLAGRYAVL MPNTARGGGI SRKITSAQDR SRLKEVVQDL 400
DVPEGMGVIL RTAGASRTKP EIKRDFEYLI RMWETVRDVT LNSQAPKLVY 450
EEGSLIKRSL RDLYNKEIDE VLVAGEAGYR EARDFMHMLM PSQVRAVKLY 500
RDGQPLFSRM GVESQLDAMF SPTVQLRSGG YIVINQTEAL VSIDVNSGRS 550
TREHHIEDTA LKTNMEAAEE VARQLRLRDL AGLIVIDFID MDEKRNNRAV 600
ERKLSDCLRQ DRARIQVGRI SHFGLLEMSR QRIRASVLES STEPCPHCGG 650
SGHVRSVSSV ALQLLRGLEE VLMKGATHNL IVRTRTDVAL YVLNHKRGHL 700
RDLETGFRVS LSVLADPTVS GQQSFVIDRG EQVHTLETAK ALLAAQIAAS 750
PAPLDEPEDD DGYDFEAEIE TDETVGLAED QGSEAGESES EGRKRRRRRR 800
RRRSGEPREA AEAGAVGEDG EQPFVSEGVE QVGEADEGDE AGEDDSDAEA 850
RADQGENGER RPRRRGRRGG RRRRGNAEAG ENEAGVVGSI SDELSPTDEA 900
EAADAVADFD GGSPSVQPSF EPAAEAEQPH DAPPHDIVPS EPQHTAATAA 950
PDTSDPSAED DSAAKKAARR RSTVREKVSF GASAAASETT AEAAAEVQPE 1000
PTAQAEQPAT AAPAVEAPAA EAAPQAAAQP AEEPSSAAPR RVGWWSRRFG 1050
GGN 1053
Length:1,053
Mass (Da):115,731
Last modified:September 2, 2008 - v1
Checksum:i630391D431EEC8AE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001096 Genomic DNA. Translation: ACF01237.1.
RefSeqiWP_012495937.1. NC_011004.1.
YP_001991712.1. NC_011004.1.

Genome annotation databases

EnsemblBacteriaiACF01237; ACF01237; Rpal_2728.
GeneIDi6410392.
KEGGirpt:Rpal_2728.
PATRICi23309912. VBIRhoPal88240_2766.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001096 Genomic DNA. Translation: ACF01237.1 .
RefSeqi WP_012495937.1. NC_011004.1.
YP_001991712.1. NC_011004.1.

3D structure databases

ProteinModelPortali B3QH48.
SMRi B3QH48. Positions 36-80.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 395960.Rpal_2728.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACF01237 ; ACF01237 ; Rpal_2728 .
GeneIDi 6410392.
KEGGi rpt:Rpal_2728.
PATRICi 23309912. VBIRhoPal88240_2766.

Phylogenomic databases

eggNOGi COG1530.
HOGENOMi HOG000258026.
KOi K08300.
OMAi PFGLLEM.
OrthoDBi EOG6PCPTH.

Enzyme and pathway databases

BioCyci RPAL395960:GHPC-2750-MONOMER.

Family and domain databases

Gene3Di 2.40.50.140. 2 hits.
HAMAPi MF_00970. RNase_E.
InterProi IPR012340. NA-bd_OB-fold.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR019307. RNA-bd_AU-1/RNase_E/G.
IPR022967. RNA-binding_domain_S1.
IPR028878. RNase_E.
IPR004659. RNase_E/G.
[Graphical view ]
Pfami PF10150. RNase_E_G. 1 hit.
PF00575. S1. 1 hit.
[Graphical view ]
SMARTi SM00316. S1. 1 hit.
[Graphical view ]
SUPFAMi SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00757. RNaseEG. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TIE-1Imported.

Entry informationi

Entry nameiB3QH48_RHOPT
AccessioniPrimary (citable) accession number: B3QH48
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: September 3, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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