Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phospho-N-acetylmuramoyl-pentapeptide-transferase

Gene

mraY

Organism
Rhodopseudomonas palustris (strain TIE-1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan.UniRule annotation

Catalytic activityi

UDP-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala) + undecaprenyl phosphate = UMP + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol.UniRule annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processCell cycle, Cell division, Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

BioCyciRPAL395960:RPAL_RS20045-MONOMER
UniPathwayiUPA00219

Names & Taxonomyi

Protein namesi
Recommended name:
Phospho-N-acetylmuramoyl-pentapeptide-transferaseUniRule annotation (EC:2.7.8.13UniRule annotation)
Alternative name(s):
UDP-MurNAc-pentapeptide phosphotransferaseUniRule annotation
Gene namesi
Name:mraYUniRule annotation
Ordered Locus Names:Rpal_4051
OrganismiRhodopseudomonas palustris (strain TIE-1)
Taxonomic identifieri395960 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
Proteomesi
  • UP000001725 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei25 – 45HelicalUniRule annotationAdd BLAST21
Transmembranei72 – 92HelicalUniRule annotationAdd BLAST21
Transmembranei95 – 115HelicalUniRule annotationAdd BLAST21
Transmembranei135 – 155HelicalUniRule annotationAdd BLAST21
Transmembranei169 – 189HelicalUniRule annotationAdd BLAST21
Transmembranei200 – 220HelicalUniRule annotationAdd BLAST21
Transmembranei240 – 260HelicalUniRule annotationAdd BLAST21
Transmembranei264 – 284HelicalUniRule annotationAdd BLAST21
Transmembranei289 – 309HelicalUniRule annotationAdd BLAST21
Transmembranei338 – 358HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000906631 – 361Phospho-N-acetylmuramoyl-pentapeptide-transferaseAdd BLAST361

Structurei

3D structure databases

SMRiB3QFN4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 4 family. MraY subfamily.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000275122
KOiK01000
OMAiLMSPLHH
OrthoDBiPOG091H00VH

Family and domain databases

CDDicd06852 GT_MraY, 1 hit
HAMAPiMF_00038 MraY, 1 hit
InterProiView protein in InterPro
IPR000715 Glycosyl_transferase_4
IPR003524 PNAcMuramoyl-5peptid_Trfase
IPR018480 PNAcMuramoyl-5peptid_Trfase_CS
PANTHERiPTHR22926 PTHR22926, 1 hit
PfamiView protein in Pfam
PF00953 Glycos_transf_4, 1 hit
PF10555 MraY_sig1, 1 hit
TIGRFAMsiTIGR00445 mraY, 1 hit
PROSITEiView protein in PROSITE
PS01347 MRAY_1, 1 hit
PS01348 MRAY_2, 1 hit

Sequencei

Sequence statusi: Complete.

B3QFN4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLYWLIDLSS SFPAFNVFRY ITFRTGGAMV TGALFVFMFG PWIIDNLRLR
60 70 80 90 100
QGKGQPIRTD GPQSHLMTKK GTPTMGGLMI LSGLTVGTVL WANPLNPYVW
110 120 130 140 150
IVLAVTLGFG FVGFYDDYMK VTKQTHAGIS GRTRLLIEFI IAGAACFALV
160 170 180 190 200
WLGRAPLSSS LVIPFFKEVM LNLGWAFVVF GAFVVVGAGN AVNLTDGLDG
210 220 230 240 250
LAIVPVMIAA ASFGLISYLA GNAVFAEYLQ INYVAGTGEL AVLCGALLGA
260 270 280 290 300
GLGFLWFNAP PASIFMGDTG SLALGGMLGS IAVAVKHEIV LAVIGGLFVL
310 320 330 340 350
EAVSVIVQVA SFKLTGKRVF KMAPIHHHFE QKGWTEPQIV IRFWIIAVML
360
ALAGLSTLKL R
Length:361
Mass (Da):38,715
Last modified:September 2, 2008 - v1
Checksum:i186292188342A032
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001096 Genomic DNA Translation: ACF02547.1
RefSeqiWP_012496968.1, NC_011004.1

Genome annotation databases

EnsemblBacteriaiACF02547; ACF02547; Rpal_4051
KEGGirpt:Rpal_4051

Similar proteinsi

Entry informationi

Entry nameiMRAY_RHOPT
AccessioniPrimary (citable) accession number: B3QFN4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 2, 2008
Last modified: June 20, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health