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B3QBT0 (PQQC_RHOPT) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Pyrroloquinoline-quinone synthase
EC=1.3.3.11
Alternative name(s):
Coenzyme PQQ synthesis protein C
Pyrroloquinoline quinone biosynthesis protein C
Gene names
Name:pqqC
Ordered Locus Names:Rpal_2159
OrganismRhodopseudomonas palustris (strain TIE-1) [Complete proteome] [HAMAP]
Taxonomic identifier395960 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Rhodopseudomonas

Protein attributes

Sequence length254 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ By similarity. HAMAP MF_00654

Catalytic activity

6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 = 4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + 2 H2O2 + 2 H2O. HAMAP MF_00654

Pathway

Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis. HAMAP MF_00654

Sequence similarities

Belongs to the pqqC family.

Ontologies

Keywords
   Biological processPQQ biosynthesis
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processpyrroloquinoline quinone biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionpyrroloquinoline-quinone synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 254254Pyrroloquinoline-quinone synthase HAMAP MF_00654
PRO_1000131180

Sequences

Sequence LengthMass (Da)Tools
B3QBT0 [UniParc].

Last modified September 2, 2008. Version 1.
Checksum: 4145E2134F93B1FC

FASTA25428,674
        10         20         30         40         50         60 
MNAMTAFSLN GAAPLANADE LEAALRQIGT ARYHNLHPFH RLLHGGKLNK GQVQAWALNR 

        70         80         90        100        110        120 
YYYQSSIPIK DAVVISRFRD RATRVEWRHR IEDHDGDLGS EGGIERWLKL TEGLGLDSGY 

       130        140        150        160        170        180 
VESTQGILPA TRFAVDAYVH FVRDRTPLEA IASSLTELFA PNLHEERIAG MLAHYDFVNP 

       190        200        210        220        230        240 
EIMSYFKRRL EQAPRDTDFA LRYVKQHATT PAEREAVCNA LIFKTNVLWA QLDALHHAYV 

       250 
DGHIPPGAFV PQGF

« Hide

References

[1]"Complete sequence of Rhodopseudomonas palustris TIE-1."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. expand/collapse author list , Emerson D., Newman D.K., Roden E., Richardson P.
Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: TIE-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001096 Genomic DNA. Translation: ACF00680.1.
RefSeqYP_001991155.1. NC_011004.1.

3D structure databases

ProteinModelPortalB3QBT0.
ModBaseSearch...

Protein-protein interaction databases

STRINGB3QBT0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6409819.
GenomeReviewsGene locus Rpal_2159 in contig CP001096_GR.
KEGGrpt:Rpal_2159.
PATRIC23308769. VBIRhoPal88240_2199.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG288944.
OMAFRDRATR.
ProtClustDBPRK05157.

Family and domain databases

HAMAPMF_00654. PQQ_syn_PqqC.
[Tree]
InterProIPR016084. Haem_Oase-like_multi-hlx.
IPR011845. PQQ_synth_PqqC.
IPR004305. TENA/THI4/PQQ_synthPqqC_dom.
[Graphical view]
Gene3DG3DSA:1.20.910.10. Haem_Oase-like_multi-hlx. 1 hit.
KOK06137.
PfamPF03070. TENA_THI-4. 1 hit.
[Graphical view]
SUPFAMSSF48613. Heme_oxygenase. 1 hit.
TIGRFAMsTIGR02111. PQQ_syn_pqqC. 1 hit.
ProtoNetSearch...

Entry information

Entry namePQQC_RHOPT
AccessionPrimary (citable) accession number: B3QBT0
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 2, 2008
Last modified: January 25, 2012
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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