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Protein

RNA pyrophosphohydrolase

Gene

rppH

Organism
Rhodopseudomonas palustris (strain TIE-1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.UniRule annotationSAAS annotation

Cofactori

a divalent metal cationUniRule annotationSAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotationImported

Names & Taxonomyi

Protein namesi
Recommended name:
RNA pyrophosphohydrolaseUniRule annotationSAAS annotation (EC:3.6.1.-UniRule annotation)
Alternative name(s):
(Di)nucleoside polyphosphate hydrolaseUniRule annotation
Gene namesi
Name:rppHUniRule annotation
Synonyms:nudHUniRule annotation
Ordered Locus Names:Rpal_0169Imported
OrganismiRhodopseudomonas palustris (strain TIE-1)Imported
Taxonomic identifieri395960 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
Proteomesi
  • UP000001725 Componenti: Chromosome

Structurei

3D structure databases

ProteinModelPortaliB3Q743.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 163Nudix hydrolaseInterPro annotationAdd BLAST153

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi52 – 73Nudix boxUniRule annotationAdd BLAST22

Sequence similaritiesi

Belongs to the Nudix hydrolase family. RppH subfamily.UniRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000066722.
KOiK08311.
OMAiPLDCVIE.
OrthoDBiPOG091H0392.

Family and domain databases

CDDicd03671. Ap4A_hydrolase_plant_like. 1 hit.
HAMAPiMF_00298. Nudix_RppH. 1 hit.
InterProiView protein in InterPro
IPR020476. Nudix_hydrolase.
IPR020084. NUDIX_hydrolase_CS.
IPR000086. NUDIX_hydrolase_dom.
IPR015797. NUDIX_hydrolase_dom-like.
IPR022927. RppH.
PfamiView protein in Pfam
PF00293. NUDIX. 1 hit.
PRINTSiPR00502. NUDIXFAMILY.
SUPFAMiSSF55811. SSF55811. 1 hit.
PROSITEiView protein in PROSITE
PS51462. NUDIX. 1 hit.
PS00893. NUDIX_BOX. 1 hit.

Sequencei

Sequence statusi: Complete.

B3Q743-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSRPPIESL PYRRNVGIAL FGADGRVLIG RRFRDDGPEI ILPGLEWQMP
60 70 80 90 100
QGGIDEGEEP RIAVMRELWE ETGVTNAEIL GETDWASYDF PPYDGPPHRL
110 120 130 140 150
AVFRGQRQKW FALRFTGSET EIDPLAVRND MPPEFDAWRW EQLDRVADLV
160 170
VPFRREVYRE VARSFARFTA AQA
Length:173
Mass (Da):19,949
Last modified:September 2, 2008 - v1
Checksum:i417B94BFEB55B4B9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001096 Genomic DNA. Translation: ACE98731.1.
RefSeqiWP_012493966.1. NC_011004.1.

Genome annotation databases

EnsemblBacteriaiACE98731; ACE98731; Rpal_0169.
KEGGirpt:Rpal_0169.

Similar proteinsi

Entry informationi

Entry nameiB3Q743_RHOPT
AccessioniPrimary (citable) accession number: B3Q743
Entry historyiIntegrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: September 27, 2017
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported