Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Catalase-peroxidase

Gene

katG

Organism
Rhizobium etli (strain CIAT 652)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.UniRule annotation

Catalytic activityi

Donor + H2O2 = oxidized donor + 2 H2O.UniRule annotation
2 H2O2 = O2 + 2 H2O.UniRule annotation

Cofactori

heme bUniRule annotationNote: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei93Transition state stabilizerUniRule annotation1
Active sitei97Proton acceptorUniRule annotation1
Metal bindingi259Iron (heme axial ligand)UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase, Peroxidase
Biological processHydrogen peroxide
LigandHeme, Iron, Metal-binding

Enzyme and pathway databases

BioCyciRETL491916:G1GBZ-5248-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Catalase-peroxidaseUniRule annotation (EC:1.11.1.21UniRule annotation)
Short name:
CPUniRule annotation
Alternative name(s):
Peroxidase/catalaseUniRule annotation
Gene namesi
Name:katGUniRule annotation
Ordered Locus Names:RHECIAT_PC0000007
Encoded oniPlasmid pC0 Publication
OrganismiRhizobium etli (strain CIAT 652)
Taxonomic identifieri491916 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
Proteomesi
  • UP000008817 Componenti: Plasmid pC

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003548831 – 728Catalase-peroxidaseAdd BLAST728

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Cross-linki96 ↔ 218Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-244)UniRule annotation
Cross-linki218 ↔ 244Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-96)UniRule annotation

Post-translational modificationi

Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.UniRule annotation

Proteomic databases

PRIDEiB3Q4F9

Interactioni

Subunit structurei

Homodimer or homotetramer.UniRule annotation

Structurei

3D structure databases

SMRiB3Q4F9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peroxidase family. Peroxidase/catalase subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000218110
KOiK03782
OrthoDBiPOG091H05R1

Family and domain databases

HAMAPiMF_01961 Catal_peroxid, 1 hit
InterProiView protein in InterPro
IPR000763 Catalase_peroxidase
IPR010255 Haem_peroxidase
IPR002016 Haem_peroxidase_pln/fun/bac
IPR019794 Peroxidases_AS
IPR019793 Peroxidases_heam-ligand_BS
PANTHERiPTHR30555 PTHR30555, 1 hit
PfamiView protein in Pfam
PF00141 peroxidase, 2 hits
PRINTSiPR00460 BPEROXIDASE
PR00458 PEROXIDASE
SUPFAMiSSF48113 SSF48113, 2 hits
TIGRFAMsiTIGR00198 cat_per_HPI, 1 hit
PROSITEiView protein in PROSITE
PS00435 PEROXIDASE_1, 1 hit
PS00436 PEROXIDASE_2, 1 hit
PS50873 PEROXIDASE_4, 1 hit

Sequencei

Sequence statusi: Complete.

B3Q4F9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDNPTDTAGK CPVAHGNKPR GPSNRDWWPN QLNVQILHHN SGRADPMGKD
60 70 80 90 100
FDYAEEFKKL DLDALKKDLT ALMTDSQDWW PADFGHYGGL FIRMAWHSAG
110 120 130 140 150
TYRITDGRGG AGQGQQRFAP LNSWPDNANL DKARRLLWPI KQKYGNRISW
160 170 180 190 200
ADLLILTGNV ALESMGFKTF GFAGGRADVW EPEELYWGPE GTWLGDERYS
210 220 230 240 250
GERQLAEPLG AVQMGLIYVN PEGPGGNPDP LASARDIRET FARMAMNDEE
260 270 280 290 300
TVALIAGGHT FGKTHGAGDP SFIGAEPEGG AIEDQGLGWK SSFGSGVGKD
310 320 330 340 350
AITAGLEVTW SQTPTKWSNY FFENLFAYEW ELTKSPAGAH QWQAKNAEAS
360 370 380 390 400
IPDAYEAGKK HLPTMLTSDL ALRFDPIYEK ISRRFLENPD QFADAFARAW
410 420 430 440 450
FKLTHRDMGP KVRYLGPEVP AEDLIWQDVI PAVDHPLVGD KDIAELKAKV
460 470 480 490 500
LATGLSVQEL VSTAWASAST FRGSDKRGGA NGARIRLAPQ KDWDANQPAQ
510 520 530 540 550
LAKVLGVLEG LQKDFNAAQT GGKKISLADM IVLAGAAGVE KAAAAGGTTV
560 570 580 590 600
SVPFTPGRMD ASEAQTDAHS FAALEPRIDG FRNYVNDKRL QFMKPEEALV
610 620 630 640 650
DRAQLLTLTG PEMTVLVGGL RVLKAGQPEH GVFTARPETL TNDFFVNLLD
660 670 680 690 700
MATQWVPAAG KDGVYEGRDR KTGAAKWTGT RVDLIFGSHS QLRAFAEVYG
710 720
QADAKEKFVK DFVAAWNKVM NADRFDLV
Length:728
Mass (Da):79,730
Last modified:November 25, 2008 - v2
Checksum:i091272AB6A487A44
GO

Sequence cautioni

The sequence ACE94090 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001077 Genomic DNA Translation: ACE94090.1 Different initiation.
RefSeqiWP_041684052.1, NC_010997.1

Genome annotation databases

EnsemblBacteriaiACE94090; ACE94090; RHECIAT_PC0000007
KEGGirec:RHECIAT_PC0000007

Similar proteinsi

Entry informationi

Entry nameiKATG_RHIE6
AccessioniPrimary (citable) accession number: B3Q4F9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 25, 2008
Last sequence update: November 25, 2008
Last modified: May 23, 2018
This is version 60 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Plasmid

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health