Reviewed, UniProtKB/Swiss-Prot B3PXL5 (PNCB_RHIE6)

Names and origin

Protein names

Recommended name:
    Nicotinate phosphoribosyltransferase
      Short name=NAPRTase
    EC=2.4.2.11

Gene names

Name:	pncB
Ordered Locus Names:	RHECIAT_CH0000225

Organism

Rhizobium etli (strain CIAT 652) [Complete proteome] [HAMAP]

Taxonomic identifier

491916 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Rhizobium

Protein attributes

Sequence length	434 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP MF_00570
Pathway	Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP MF_00570
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the NAPRTase family.

Ontologies

Keywords
Biological process	Pyridine nucleotide biosynthesis
Cellular component	Cytoplasm
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	NAD biosynthetic process Inferred from electronic annotation. Source: HAMAP nicotinate nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nicotinate phosphoribosyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 434	434	Nicotinate phosphoribosyltransferase HAMAP MF_00570		PRO_1000129480

Sequences

	Sequence		Length	Mass (Da)
	B3PXL5-1 [UniParc]. Last modified September 2, 2008. Version 1. Checksum: 940F61E09C1D41FE	FASTA	434	49,501
	10 20 30 40 50 60 MAKTDIARRV YNHAWKLDPI IRSLIDTDFY KLLMLQMIWK LYPDVNASFT LINRTKRVHL 70 80 90 100 110 120 AEEIDEGELR EQLDHARTLR LSKKEMIWLA GNSFYGRAQI FEPEFLAWLS NFQLPEYELS 130 140 150 160 170 180 KKDGQYVLDF HGAWKETTMW EIPALAIVNE LRSRSAMKAL GPFTLDVLYA RAKAKMWSKV 190 200 210 220 230 240 ERLRELPGLR ISDFGTRRRH SFLWQRWCVE ALKEGIGPAF TGTSNVLLAM DSDLEAVGTN 250 260 270 280 290 300 AHELPMVAAA LAQTDEQLRN APYKILRDWN KLYGGNLLIV LPDAFGTAAF LRDAPEWVAD 310 320 330 340 350 360 WTGFRPDSAP PIEGGEKIID WWKKMGRDPR QKLLIFSDGL DVDAIIDTYR HFEGRVRMSF 370 380 390 400 410 420 GWGTNLTNDF AGCAPTEISG LNPISVVCKV SDANGRPAVK LSDNPQKATG EPAEVERYLK 430 FFGTEDRVDQ TVLV

References

[1]

"Genome diversity and DNA divergence of Rhizobium etli." Gonzalez V., Acosta J.L., Santamaria R.I., Bustos P., Hernandez-Gonzalez I.L., Fernandez J.L., Diaz R., Flores M., Mora J., Palacios R., Davila G. Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP001074 Genomic DNA. Translation: ACE89221.1.
RefSeq	YP_001976399.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6398099.
GenomeReviews	Gene locus pncB in contig CP001074_GR.
KEGG	rec:RHECIAT_CH0000225.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	ALTDTFG.
Family and domain databases
HAMAP	MF_00570. [Tree]
InterPro	IPR006406. Nic_PRibTrfase. IPR015977. Nic_PRibTrfase-like. IPR007229. Nic_PRibTrfase-rel. [Graphical view]
PANTHER	PTHR11098:SF1. NAPRTase. 1 hit.
Pfam	PF04095. NAPRTase. 1 hit. [Graphical view]
PIRSF	PIRSF000484. NAPRT. 1 hit.
TIGRFAMs	TIGR01514. NAPRTase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PNCB_RHIE6

Accession

Primary (citable) accession number: B3PXL5

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	September 2, 2008
Last modified:	November 3, 2009
This is version 12 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)