B3PXI8 (PHNN_RHIE6) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribose 1,5-bisphosphate phosphokinase PhnN
EC=2.7.4.23

Alternative name(s):
Ribose 1,5-bisphosphokinase

Gene names

Name:	phnN
Ordered Locus Names:	RHECIAT_CH0000198

Organism

Rhizobium etli (strain CIAT 652) [Complete proteome] [HAMAP]

Taxonomic identifier

491916 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Rhizobium › Rhizobium etli

Protein attributes

Sequence length	197 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) By similarity. HAMAP-Rule MF_00836
Catalytic activity	ATP + alpha-D-ribose 1,5-bisphosphate = ADP + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP-Rule MF_00836
Pathway	Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II): step 3/3. HAMAP-Rule MF_00836
Sequence similarities	Belongs to the ribose 1,5-bisphosphokinase family.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	5-phosphoribose 1-diphosphate biosynthetic process Inferred from electronic annotation. Source: HAMAP organic phosphonate metabolic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ribose 1,5-bisphosphate phosphokinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 197	197	Ribose 1,5-bisphosphate phosphokinase PhnN HAMAP-Rule MF_00836		PRO_0000412797
Regions
	Nucleotide binding	21 – 28	8	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	B3PXI8 [UniParc]. Last modified September 2, 2008. Version 1. Checksum: 9929467E725A853C	FASTA	197	21,102
	10 20 30 40 50 60 MTHEPHPGAG AERGIMVVVV GPSGAGKDTL MNLAARHFSG RADVHFTRRV ITRHRGAGGE 70 80 90 100 110 120 DHLSVSLQGF AAMEQSGSFA VWWEAHGLKY GIPAEVSVAL SKGHIVVANG SRSALHRFQA 130 140 150 160 170 180 AFPRLKVINV TASAEVLAGR LEARGRETHE DIMARLARGP LTVRGDYDVT ELDNSGSIEE 190 AEQKMIAILD GLLAEVH

References

[1]

"Genome diversity and DNA divergence of Rhizobium etli." Gonzalez V., Acosta J.L., Santamaria R.I., Bustos P., Hernandez-Gonzalez I.L., Fernandez J.L., Diaz R., Flores M., Mora J., Palacios R., Davila G. Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CIAT 652.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001074 Genomic DNA. Translation: ACE89194.1.
RefSeq	YP_001976372.1. NC_010994.1.
3D structure databases
ProteinModelPortal	B3PXI8.
ModBase	Search...
Protein-protein interaction databases
STRING	491916.RHECIAT_CH0000198.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACE89194; ACE89194; RHECIAT_CH0000198.
GeneID	6398497.
KEGG	rec:RHECIAT_CH0000198.
PATRIC	23093858. VBIRhiEtl120572_0198.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3709.
HOGENOM	HOG000037637.
KO	K05774.
OMA	KVINVTA.
ProtClustDB	CLSK557418.
Enzyme and pathway databases
BioCyc	RETL491916:GH4T-1951-MONOMER.
UniPathway	UPA00087; UER00175.
Family and domain databases
HAMAP	MF_00836. PhnN.
InterPro	IPR008144. Guanylate_kin. IPR008145. Guanylate_kin/L-typ_Ca_channel. IPR012699. PhnN. [Graphical view]
Pfam	PF00625. Guanylate_kin. 1 hit. [Graphical view]
SMART	SM00072. GuKc. 1 hit. [Graphical view]
TIGRFAMs	TIGR02322. phosphon_PhnN. 1 hit.
PROSITE	PS50052. GUANYLATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PHNN_RHIE6

Accession

Primary (citable) accession number: B3PXI8

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 21, 2011
Last sequence update:	September 2, 2008
Last modified:	May 1, 2013
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program