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Protein

Arginine deiminase

Gene

arcA

Organism
Rhizobium etli (strain CIAT 652)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-arginine + H2O = L-citrulline + NH3.UniRule annotation

Pathwayi: L-arginine degradation via ADI pathway

This protein is involved in step 1 of the subpathway that synthesizes carbamoyl phosphate from L-arginine.UniRule annotation
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. Arginine deiminase (arcA)
  2. no protein annotated in this organism
This subpathway is part of the pathway L-arginine degradation via ADI pathway, which is itself part of Amino-acid degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes carbamoyl phosphate from L-arginine, the pathway L-arginine degradation via ADI pathway and in Amino-acid degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei398Amidino-cysteine intermediateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processArginine metabolism

Enzyme and pathway databases

BioCyciRETL491916:G1GBZ-130-MONOMER
UniPathwayiUPA00254; UER00364

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine deiminaseUniRule annotation (EC:3.5.3.6UniRule annotation)
Short name:
ADIUniRule annotation
Alternative name(s):
Arginine dihydrolaseUniRule annotation
Short name:
ADUniRule annotation
Gene namesi
Name:arcAUniRule annotation
Ordered Locus Names:RHECIAT_CH0000128
OrganismiRhizobium etli (strain CIAT 652)
Taxonomic identifieri491916 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
Proteomesi
  • UP000008817 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001007421 – 409Arginine deiminaseAdd BLAST409

Interactioni

Protein-protein interaction databases

STRINGi491916.RHECIAT_CH0000128

Structurei

3D structure databases

ProteinModelPortaliB3PWQ6
SMRiB3PWQ6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the arginine deiminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CEU Bacteria
COG2235 LUCA
HOGENOMiHOG000284536
KOiK01478
OMAiQERATMH
OrthoDBiPOG091H06H4

Family and domain databases

HAMAPiMF_00242 Arg_deiminase, 1 hit
InterProiView protein in InterPro
IPR003876 Arg_deiminase
IPR033199 DDAH/AD
PANTHERiPTHR12737 PTHR12737, 1 hit
PTHR12737:SF22 PTHR12737:SF22, 1 hit
PIRSFiPIRSF006356 Arg_deiminase, 1 hit
PRINTSiPR01466 ARGDEIMINASE
TIGRFAMsiTIGR01078 arcA, 1 hit

Sequencei

Sequence statusi: Complete.

B3PWQ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRGFGVHSEV GKLRTVMVCR PSLAHQRLTP ANCHDLLFDD VLWVHEAQKD
60 70 80 90 100
HFDFVLKMQE RGVEVLELHD LLGQTLANQQ ARDFLLDRRI TPNVLGSQIA
110 120 130 140 150
EAMRPWLDEM PAAQLAAFMI GGIAISDLPE VRAKSLMLSA LPETDFVIPP
160 170 180 190 200
IPNTLFQRDP SCWIYGGVTC NPMFWPARRA ETLIQRAIYK FHPIFLGGDF
210 220 230 240 250
QIWWGDSDQP FANASMEGGD VMPIGNGTVL IGMGERTTYQ AVGQVAQALF
260 270 280 290 300
RSKAAKRVIG CLMPKSRAAM HLDTVFSFCD RDVVTLFAEV VDQVRCYSMY
310 320 330 340 350
PKDDDGTFEI HPENRPMLDV VAEALDLPQL RTVETGGNSY QAEREQWDDG
360 370 380 390 400
NNVVALEPGV VVAYDRNTYT NTLLRKAGIE VITIRGSELG RGRGGGHCMT

CPIWRDPAY
Length:409
Mass (Da):45,712
Last modified:September 2, 2008 - v1
Checksum:i920A434DA72A3B3A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001074 Genomic DNA Translation: ACE89124.1
RefSeqiWP_012482189.1, NC_010994.1

Genome annotation databases

EnsemblBacteriaiACE89124; ACE89124; RHECIAT_CH0000128
KEGGirec:RHECIAT_CH0000128

Similar proteinsi

Entry informationi

Entry nameiARCA_RHIE6
AccessioniPrimary (citable) accession number: B3PWQ6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 2, 2008
Last modified: April 25, 2018
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health