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B3PTE1 (BETB_RHIE6) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Betaine aldehyde dehydrogenase
Short name=BADH
EC=1.2.1.8
Gene names
Name:betB
Ordered Locus Names:RHECIAT_CH0001220
OrganismRhizobium etli (strain CIAT 652) [Complete proteome] [HAMAP]
Taxonomic identifier491916 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Rhizobium

Protein attributes

Sequence length487 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Betaine aldehyde + NAD+ + H2O = betaine + NADH. HAMAP MF_00804

Pathway

Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine from betaine aldehyde: step 1/1. HAMAP MF_00804

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processbetaine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionbetaine-aldehyde dehydrogenase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 487487Betaine aldehyde dehydrogenase HAMAP MF_00804
PRO_1000133957

Regions

Nucleotide binding228 – 2336NAD By similarity

Sites

Active site2501 By similarity
Active site2841 By similarity

Sequences

Sequence LengthMass (Da)Tools
B3PTE1 [UniParc].

Last modified September 2, 2008. Version 1.
Checksum: 2E71E2C662F4CCD0

FASTA48751,692
        10         20         30         40         50         60 
MKAQPKASHF IDGEYVEDSD GTVIESLYPA TGEVIARLHA ATPAIVEKAI AAAKSAQPEW 

        70         80         90        100        110        120 
AAMSPMARGR ILKRAADIMR ERNRELSELE TLDTGKPIQE TIVADPTSGA DAFEFFGGVA 

       130        140        150        160        170        180 
PAGLNGSHIP LGQDFAYTKR VPLGVCVGIG AWNYPQQIAC WKGAPALIAG NAMVFKPSEN 

       190        200        210        220        230        240 
TPLGALKIAE ILHEAGLPKG LFNVIQGDRD TGPLLVNHPD VAKVSLTGSV PTGRRVAAAA 

       250        260        270        280        290        300 
AGSLKHVTME LGGKSPLIVF DDADLDSAVG GAMLGNFYST GQVCSNGTRV FVQKGIKTEF 

       310        320        330        340        350        360 
LKRLKARTEA MLIGDPMDEA TQIGPMVSWA QREKVVAYIE KGKAEGATLV AGGGIPNNVS 

       370        380        390        400        410        420 
GEGYYVQPTV FADVTDEMTI AREEIFGPVM SVLDFDDEDE VITRANASEF GLSGGVFTAD 

       430        440        450        460        470        480 
LTRAHRVVDR LEAGTLWINA YNLAPVEIPF GGSKQSGFGR ENSLAALEHY SELKTVYVGM 


GPVQAPY

« Hide

References

[1]"Genome diversity and DNA divergence of Rhizobium etli."
Gonzalez V., Acosta J.L., Santamaria R.I., Bustos P., Hernandez-Gonzalez I.L., Fernandez J.L., Diaz R., Flores M., Mora J., Palacios R., Davila G.
Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CIAT 652.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001074 Genomic DNA. Translation: ACE90201.1.
RefSeqYP_001977379.1. NC_010994.1.

3D structure databases

ProteinModelPortalB3PTE1.
ModBaseSearch...

Protein-protein interaction databases

STRINGB3PTE1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6399307.
GenomeReviewsGene locus betB in contig CP001074_GR.
KEGGrec:RHECIAT_CH0001220.
PATRIC23095860. VBIRhiEtl120572_1187.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG752218.
OMAIMRERNR.
ProtClustDBPRK13252.

Family and domain databases

HAMAPMF_00804. BADH.
[Tree]
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR011264. Betaine_Ald_DH.
[Graphical view]
Gene3DG3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit.
G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KOK00130.
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMsTIGR01804. BADH. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBETB_RHIE6
AccessionPrimary (citable) accession number: B3PTE1
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 2, 2008
Last modified: January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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