Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Ribosomal RNA large subunit methyltransferase H

Gene

rlmH

Organism
Rhizobium etli (strain CIAT 652)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + pseudouridine(1915) in 23S rRNA = S-adenosyl-L-homocysteine + N3-methylpseudouridine(1915) in 23S rRNA.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei76S-adenosyl-L-methionine; via carbonyl oxygenUniRule annotation1
Binding sitei108S-adenosyl-L-methionine; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processrRNA processing
LigandS-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA large subunit methyltransferase HUniRule annotation (EC:2.1.1.177UniRule annotation)
Alternative name(s):
23S rRNA (pseudouridine1915-N3)-methyltransferaseUniRule annotation
23S rRNA m3Psi1915 methyltransferaseUniRule annotation
rRNA (pseudouridine-N3-)-methyltransferase RlmHUniRule annotation
Gene namesi
Name:rlmHUniRule annotation
Ordered Locus Names:RHECIAT_CH0004366
OrganismiRhizobium etli (strain CIAT 652)
Taxonomic identifieri491916 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
Proteomesi
  • UP000008817 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003666441 – 160Ribosomal RNA large subunit methyltransferase HAdd BLAST160

Proteomic databases

PRIDEiB3PS03

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi491916.RHECIAT_CH0004366

Structurei

3D structure databases

ProteinModelPortaliB3PS03
SMRiB3PS03
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni127 – 132S-adenosyl-L-methionine bindingUniRule annotation6

Sequence similaritiesi

Belongs to the RNA methyltransferase RlmH family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UXA Bacteria
COG1576 LUCA
HOGENOMiHOG000218433
KOiK00783
OMAiNGEPYHK
OrthoDBiPOG091H028B

Family and domain databases

Gene3Di3.40.1280.10, 1 hit
HAMAPiMF_00658 23SrRNA_methyltr_H, 1 hit
InterProiView protein in InterPro
IPR029028 Alpha/beta_knot_MTases
IPR003742 RlmH-like
IPR029026 tRNA_m1G_MTases_N
PANTHERiPTHR33603 PTHR33603, 1 hit
PfamiView protein in Pfam
PF02590 SPOUT_MTase, 1 hit
PIRSFiPIRSF004505 MT_bac, 1 hit
SUPFAMiSSF75217 SSF75217, 1 hit

Sequencei

Sequence statusi: Complete.

B3PS03-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRVGLFAVGR LKSGPEKDLA ARYFDRFAKA GPAVGLELAR IAETAESRAS
60 70 80 90 100
NAETRKREEA AILLKSLAEG SVLILLDERG KALDSEAFAN LLGAYRDQGK
110 120 130 140 150
RDLMIAIGGA DGLDPALYDR ADVTLCLGKM TWPHQLVRTL IAEQLYRAVT
160
ILSGHPYHRV
Length:160
Mass (Da):17,463
Last modified:September 2, 2008 - v1
Checksum:iD3BFEE81A899602C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001074 Genomic DNA Translation: ACE93293.1
RefSeqiWP_012485644.1, NC_010994.1

Genome annotation databases

EnsemblBacteriaiACE93293; ACE93293; RHECIAT_CH0004366
KEGGirec:RHECIAT_CH0004366

Similar proteinsi

Entry informationi

Entry nameiRLMH_RHIE6
AccessioniPrimary (citable) accession number: B3PS03
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 2, 2008
Last modified: May 23, 2018
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health