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B3PPT2

- GLSA_RHIE6

UniProt

B3PPT2 - GLSA_RHIE6

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Protein

Glutaminase

Gene
glsA, RHECIAT_CH0002407
Organism
Rhizobium etli (strain CIAT 652)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei64 – 641Substrate By similarity
Binding sitei114 – 1141Substrate By similarity
Binding sitei160 – 1601Substrate By similarity
Binding sitei167 – 1671Substrate By similarity
Binding sitei191 – 1911Substrate By similarity
Binding sitei243 – 2431Substrate By similarity
Binding sitei261 – 2611Substrate; via amide nitrogen By similarity

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciRETL1328306-WGS:GSTH-2320-MONOMER.
RETL491916:GH4T-2406-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase (EC:3.5.1.2)
Gene namesi
Name:glsA
Ordered Locus Names:RHECIAT_CH0002407
OrganismiRhizobium etli (strain CIAT 652)
Taxonomic identifieri491916 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
ProteomesiUP000008817: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 309309GlutaminaseUniRule annotationPRO_1000115701Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi491916.RHECIAT_CH0002407.

Structurei

3D structure databases

ProteinModelPortaliB3PPT2.

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiQRARRIN.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

B3PPT2-1 [UniParc]FASTAAdd to Basket

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MADLKAILDS IYTDILPRVG EGKVADYIPE LAKVDPRQFG MAIVTVDGKV    50
YRVGDADIAF SIQSISKVFM LTLALGKVGE GLWKRVGREP SGSAFNSIVQ 100
LEHESGIPRN PFINAGAIAV TDVVMAGHAP REAIGELLRF VRYLADDESI 150
TIDDKVARSE TQTGYRNVAL ANFMRAYRNL DHPVDHVLGV YFHQCALSMS 200
CEQLARAGLF LAARGSNPMT GHSVVSPKRA RRINALMLTC GHYDGSGDFA 250
YHVGLPGKSG VGGGIFAVAP GIASIAVWSP GLNKVGNSQL GAVALEMLAA 300
RTGWSVFGD 309
Length:309
Mass (Da):33,003
Last modified:September 2, 2008 - v1
Checksum:i59E24CFDF4176750
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001074 Genomic DNA. Translation: ACE91361.1.
RefSeqiYP_001978539.1. NC_010994.1.

Genome annotation databases

EnsemblBacteriaiACE91361; ACE91361; RHECIAT_CH0002407.
GeneIDi6400494.
KEGGirec:RHECIAT_CH0002407.
PATRICi23098302. VBIRhiEtl120572_2385.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001074 Genomic DNA. Translation: ACE91361.1 .
RefSeqi YP_001978539.1. NC_010994.1.

3D structure databases

ProteinModelPortali B3PPT2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 491916.RHECIAT_CH0002407.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACE91361 ; ACE91361 ; RHECIAT_CH0002407 .
GeneIDi 6400494.
KEGGi rec:RHECIAT_CH0002407.
PATRICi 23098302. VBIRhiEtl120572_2385.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi QRARRIN.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci RETL1328306-WGS:GSTH-2320-MONOMER.
RETL491916:GH4T-2406-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome diversity and DNA divergence of Rhizobium etli."
    Gonzalez V., Acosta J.L., Santamaria R.I., Bustos P., Hernandez-Gonzalez I.L., Fernandez J.L., Diaz R., Flores M., Mora J., Palacios R., Davila G.
    Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CIAT 652.

Entry informationi

Entry nameiGLSA_RHIE6
AccessioniPrimary (citable) accession number: B3PPT2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 2, 2008
Last modified: July 9, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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