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B3PM19 (SYR_MYCA5) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:MARTH_orf134
OrganismMycoplasma arthritidis (strain 158L3-1) [Complete proteome] [HAMAP]
Taxonomic identifier243272 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length541 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 541541Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000095381

Regions

Motif123 – 13311"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
B3PM19 [UniParc].

Last modified September 2, 2008. Version 1.
Checksum: 39FFAF7DBE0FF235

FASTA54161,896
        10         20         30         40         50         60 
MITTKEIIIA SLNEALEKLE IKKPITLTEP KSYGDYSTNL ALTLQKELGK PAIEIAKEIV 

        70         80         90        100        110        120 
NAIDLKKHKE IVKVEVANPG FINFWVSNSV LSDLVNSINS LEDHYGDMSK EGKGAVNIEF 

       130        140        150        160        170        180 
VSANPTGFLH IGHARNAAIG ATLCNVLEKA GHRVVREYYV NDYGNQMNNL AASVFSRYQQ 

       190        200        210        220        230        240 
IFNKDFPMPD DAYKGHDMTI FADAFFKKYG DKYRNVAYTE EVKKLFRDFG REIALENIKI 

       250        260        270        280        290        300 
DLGRFGVWFD LYTSETQQYE KDRVWPVIRR LKSTYEKDGA TWLNTTKGGN DDKDRVIIKG 

       310        320        330        340        350        360 
NGESTYMCAD IAYHEQKFVE LHDPEKGKII DIWGADHSGY VERIKFSFED LGWRRDQIEI 

       370        380        390        400        410        420 
LLFQLLRVVK NGKEIKMSKR LGTSLTLREL LDLVGKDAVR YFLIERSYNS KIDFDINKVQ 

       430        440        450        460        470        480 
KSDETNPLFL IKYAHARCYQ LLEKAQIKNP IASNLENDFA QKLTNELKEY PNLIDTMAKT 

       490        500        510        520        530        540 
YKVNLLPPYL LKLAGAFNSF YSNVRISGDP NEQSYLALVK ATKIVLANAM KLMDLDIPNK 


M 

« Hide

References

[1]"Genome of Mycoplasma arthritidis."
Dybvig K., Zuhua C., Lao P., Jordan D.S., French C.T., Tu A.H., Loraine A.E.
Infect. Immun. 76:4000-4008(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 158L3-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001047 Genomic DNA. Translation: ACF07071.1.
RefSeqYP_001999775.1. NC_011025.1.

3D structure databases

ProteinModelPortalB3PM19.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243272.MARTH_orf134.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACF07071; ACF07071; MARTH_orf134.
GeneID6418240.
KEGGmat:MARTH_orf134.
PATRIC20003305. VBIMycArt31993_0104.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMANPNGPLH.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycMART243272:GHIZ-105-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_MYCA5
AccessionPrimary (citable) accession number: B3PM19
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 2, 2008
Last modified: April 16, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries