Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

Gene

apaH

Organism
Cellvibrio japonicus (strain Ueda107) (Pseudomonas fluorescens subsp. cellulosa)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.UniRule annotation

Catalytic activityi

P1,P(4)-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP.UniRule annotation

GO - Molecular functioni

  1. bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciCJAP498211:GHIT-863-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetricalUniRule annotation (EC:3.6.1.41UniRule annotation)
Alternative name(s):
Ap4A hydrolaseUniRule annotation
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolaseUniRule annotation
Diadenosine tetraphosphataseUniRule annotation
Gene namesi
Name:apaHUniRule annotation
Ordered Locus Names:CJA_0863
OrganismiCellvibrio japonicus (strain Ueda107) (Pseudomonas fluorescens subsp. cellulosa)
Taxonomic identifieri498211 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaeCellvibrio
ProteomesiUP000001036 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 270270Bis(5'-nucleosyl)-tetraphosphatase, symmetricalPRO_1000099318Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi498211.CJA_0863.

Structurei

3D structure databases

ProteinModelPortaliB3PKV6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Ap4A hydrolase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0639.
HOGENOMiHOG000251871.
KOiK01525.
OMAiMPWFDVP.
OrthoDBiEOG66B3WP.

Family and domain databases

Gene3Di3.60.21.10. 2 hits.
HAMAPiMF_00199. ApaH.
InterProiIPR004617. ApaH.
IPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PIRSFiPIRSF000903. B5n-ttraPtase_sm. 1 hit.
SUPFAMiSSF56300. SSF56300. 1 hit.
TIGRFAMsiTIGR00668. apaH. 1 hit.

Sequencei

Sequence statusi: Complete.

B3PKV6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATYAIGDIQ GCYEPLQCLL EKIDFDTAKD KLWLVGDLIN RGPDSLATLR
60 70 80 90 100
FLYSIRSSLE VVLGNHDLHL LAVYFGLRKQ NKSDTLTPIL EAPDAPELIH
110 120 130 140 150
WLRQQKLMHH DATLGYALVH AGIPPIWSLD KALACAREVE DYLRGPDFKT
160 170 180 190 200
FLAHMYGNQP SVWDDSLQGQ ERLRLITNYF TRMRFCSADG ELELTTKENA
210 220 230 240 250
AAAPPGFAPW FSFMQRKTRQ DRILFGHWAA LEGQVSTANV YALDTGCVWG
260 270
GYLTAMCLET GALVQCACEA
Length:270
Mass (Da):30,303
Last modified:September 1, 2008 - v1
Checksum:iB702F700390E2698
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000934 Genomic DNA. Translation: ACE84062.1.
RefSeqiWP_012486524.1. NC_010995.1.
YP_001981371.1. NC_010995.1.

Genome annotation databases

EnsemblBacteriaiACE84062; ACE84062; CJA_0863.
KEGGicja:CJA_0863.
PATRICi21325105. VBICelJap122165_0857.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000934 Genomic DNA. Translation: ACE84062.1.
RefSeqiWP_012486524.1. NC_010995.1.
YP_001981371.1. NC_010995.1.

3D structure databases

ProteinModelPortaliB3PKV6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi498211.CJA_0863.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACE84062; ACE84062; CJA_0863.
KEGGicja:CJA_0863.
PATRICi21325105. VBICelJap122165_0857.

Phylogenomic databases

eggNOGiCOG0639.
HOGENOMiHOG000251871.
KOiK01525.
OMAiMPWFDVP.
OrthoDBiEOG66B3WP.

Enzyme and pathway databases

BioCyciCJAP498211:GHIT-863-MONOMER.

Family and domain databases

Gene3Di3.60.21.10. 2 hits.
HAMAPiMF_00199. ApaH.
InterProiIPR004617. ApaH.
IPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PIRSFiPIRSF000903. B5n-ttraPtase_sm. 1 hit.
SUPFAMiSSF56300. SSF56300. 1 hit.
TIGRFAMsiTIGR00668. apaH. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Insights into plant cell wall degradation from the genome sequence of the soil bacterium Cellvibrio japonicus."
    DeBoy R.T., Mongodin E.F., Fouts D.E., Tailford L.E., Khouri H., Emerson J.B., Mohamoud Y., Watkins K., Henrissat B., Gilbert H.J., Nelson K.E.
    J. Bacteriol. 190:5455-5463(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Ueda107.

Entry informationi

Entry nameiAPAH_CELJU
AccessioniPrimary (citable) accession number: B3PKV6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 23, 2009
Last sequence update: September 1, 2008
Last modified: March 31, 2015
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.