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B3PKV6 (APAH_CELJU) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

EC=3.6.1.41
Alternative name(s):
Ap4A hydrolase
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase
Diadenosine tetraphosphatase
Gene names
Name:apaH
Ordered Locus Names:CJA_0863
OrganismCellvibrio japonicus (strain Ueda107) (Pseudomonas fluorescens subsp. cellulosa) [Complete proteome] [HAMAP]
Taxonomic identifier498211 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaeCellvibrio

Protein attributes

Sequence length270 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP By similarity. HAMAP-Rule MF_00199

Catalytic activity

P1,P(4)-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP. HAMAP-Rule MF_00199

Sequence similarities

Belongs to the Ap4A hydrolase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular_functionbis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 270270Bis(5'-nucleosyl)-tetraphosphatase, symmetrical HAMAP-Rule MF_00199
PRO_1000099318

Sequences

Sequence LengthMass (Da)Tools
B3PKV6 [UniParc].

Last modified September 2, 2008. Version 1.
Checksum: B702F700390E2698

FASTA27030,303
        10         20         30         40         50         60 
MATYAIGDIQ GCYEPLQCLL EKIDFDTAKD KLWLVGDLIN RGPDSLATLR FLYSIRSSLE 

        70         80         90        100        110        120 
VVLGNHDLHL LAVYFGLRKQ NKSDTLTPIL EAPDAPELIH WLRQQKLMHH DATLGYALVH 

       130        140        150        160        170        180 
AGIPPIWSLD KALACAREVE DYLRGPDFKT FLAHMYGNQP SVWDDSLQGQ ERLRLITNYF 

       190        200        210        220        230        240 
TRMRFCSADG ELELTTKENA AAAPPGFAPW FSFMQRKTRQ DRILFGHWAA LEGQVSTANV 

       250        260        270 
YALDTGCVWG GYLTAMCLET GALVQCACEA 

« Hide

References

[1]"Insights into plant cell wall degradation from the genome sequence of the soil bacterium Cellvibrio japonicus."
DeBoy R.T., Mongodin E.F., Fouts D.E., Tailford L.E., Khouri H., Emerson J.B., Mohamoud Y., Watkins K., Henrissat B., Gilbert H.J., Nelson K.E.
J. Bacteriol. 190:5455-5463(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Ueda107.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000934 Genomic DNA. Translation: ACE84062.1.
RefSeqYP_001981371.1. NC_010995.1.

3D structure databases

ProteinModelPortalB3PKV6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING498211.CJA_0863.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACE84062; ACE84062; CJA_0863.
GeneID6415468.
KEGGcja:CJA_0863.
PATRIC21325105. VBICelJap122165_0857.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0639.
HOGENOMHOG000251871.
KOK01525.
OMAINAFTRM.
OrthoDBEOG66B3WP.

Enzyme and pathway databases

BioCycCJAP498211:GHIT-863-MONOMER.

Family and domain databases

Gene3D3.60.21.10. 2 hits.
HAMAPMF_00199. ApaH.
InterProIPR004617. ApaH.
IPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
[Graphical view]
PfamPF00149. Metallophos. 1 hit.
[Graphical view]
PIRSFPIRSF000903. B5n-ttraPtase_sm. 1 hit.
SUPFAMSSF56300. SSF56300. 1 hit.
TIGRFAMsTIGR00668. apaH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAPAH_CELJU
AccessionPrimary (citable) accession number: B3PKV6
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 2, 2008
Last modified: June 11, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families