Reviewed, UniProtKB/Swiss-Prot B3PI82 (GCST_CELJU)

Names and origin

Protein names

Recommended name:
    Aminomethyltransferase
    EC=2.1.2.10
Alternative name(s):
    Glycine cleavage system T protein

Gene names

Name:	gcvT
Ordered Locus Names:	CJA_0421

Organism

Cellvibrio japonicus (strain Ueda107) [Complete proteome] [HAMAP]

Taxonomic identifier

498211 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Cellvibrio

Protein attributes

Sequence length	371 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	The glycine cleavage system catalyzes the degradation of glycine By similarity.
Catalytic activity	[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. HAMAP MF_00259
Subunit structure	The glycine cleavage system is composed of four proteins: P, T, L and H By similarity.
Sequence similarities	Belongs to the gcvT family.

Ontologies

Keywords
Molecular function	Aminotransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine decarboxylation via glycine cleavage system Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	aminomethyltransferase activity Inferred from electronic annotation. Source: HAMAP transaminase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 371	371	Aminomethyltransferase HAMAP MF_00259		PRO_1000114085

Sequences

	Sequence		Length	Mass (Da)
	B3PI82-1 [UniParc]. Last modified September 2, 2008. Version 1. Checksum: 9680ABFA0194D4E1	FASTA	371	40,220
	10 20 30 40 50 60 MGNKTALYDI HQSMGGKIVD FGGWDMPLHY GSQIDEHHKV RQHAGMFDVS HMTVVDVTGS 70 80 90 100 110 120 DAKAYLQYLL ANDVAKLDNL VGKALYSGML NEQGGVIDDL IVYNMGDWYR VVVNCSTREK 130 140 150 160 170 180 DLAWMSQVAN NYQVKLQERA DLAMIAVQGP QAIAITKTLV SAEAATLIDN LQVFQGLAST 190 200 210 220 230 240 QQGSDWFFGR TGYTGEDGLE IMLPNEQAGT FWQALAAAGV APCGLGARDT LRLEAGMNLY 250 260 270 280 290 300 GHEMDENISP LAANMGWTIA WQPEARNFIG RAALTAEKSA GQRHKLVGLV LRERGVLRAE 310 320 330 340 350 360 QLVHIANSDE RGVITSGTFS PSLGYSIALA RVPVTQVPLT PGAQCQVEMR GKLVTVDVVA 370 PGFVRQGKAL V

References

[1]

"Insights into plant cell wall degradation from the genome sequence of the soil bacterium Cellvibrio japonicus." DeBoy R.T., Mongodin E.F., Fouts D.E., Tailford L.E., Khouri H., Emerson J.B., Mohamoud Y., Watkins K., Henrissat B., Gilbert H.J., Nelson K.E. J. Bacteriol. 190:5455-5463(2008) [PubMed: 18556790] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000934 Genomic DNA. Translation: ACE85491.1.
RefSeq	YP_001980945.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6416433.
GenomeReviews	Gene locus CJA_0421 in contig CP000934_GR.
KEGG	cja:CJA_0421.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	VEIRGKW.
Family and domain databases
HAMAP	MF_00259. [Tree]
InterPro	IPR013977. GCV_T_C. IPR006222. GCV_T_N. IPR006223. GcvT. [Graphical view]
Pfam	PF01571. GCV_T. 1 hit. PF08669. GCV_T_C. 1 hit. [Graphical view]
PIRSF	PIRSF006487. GcvT. 1 hit.
TIGRFAMs	TIGR00528. gcvT. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GCST_CELJU

Accession

Primary (citable) accession number: B3PI82

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	September 2, 2008
Last modified:	November 3, 2009
This is version 10 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)