B3PD57 (ARAA_CELJU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
L-arabinose isomerase
EC=5.3.1.4

Gene names

Name:	araA
Ordered Locus Names:	CJA_3015

Organism

Cellvibrio japonicus (strain Ueda107) (Pseudomonas fluorescens subsp. cellulosa) [Complete proteome] [HAMAP]

Taxonomic identifier

498211 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Cellvibrio

Protein attributes

Sequence length	500 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of L-arabinose to L-ribulose By similarity. HAMAP MF_00519
Catalytic activity	L-arabinose = L-ribulose. HAMAP MF_00519
Cofactor	Binds 1 manganese ion per subunit By similarity. HAMAP MF_00519
Pathway	Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 1/3. HAMAP MF_00519
Sequence similarities	Belongs to the arabinose isomerase family.

Ontologies

Keywords
Biological process	Arabinose catabolism Carbohydrate metabolism
Ligand	Manganese Metal-binding
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arabinose catabolic process Inferred from electronic annotation. Source: UniProtKB-KW fucose metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	L-arabinose isomerase activity Inferred from electronic annotation. Source: EC L-fucose isomerase activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 500	500	L-arabinose isomerase HAMAP MF_00519		PRO_1000127598
Sites
	Metal binding	306	1	Manganese By similarity
	Metal binding	333	1	Manganese By similarity
	Metal binding	349	1	Manganese By similarity
	Metal binding	448	1	Manganese By similarity

Sequences

	Sequence		Length	Mass (Da)
	B3PD57 [UniParc]. Last modified September 2, 2008. Version 1. Checksum: 70BEF23E0F2029BB	FASTA	500	55,099
	10 20 30 40 50 60 MKVYGDKEVW LVTGSQHLYG PGVLKQVAEN SQKIAAGLTE SSLVSIKVVA QETVKSPGEI 70 80 90 100 110 120 LAVAQAANSN PNCVGLILWM HTFSPAKMWI GGLRALNKPY MHLHTQFNAE LPFSDINMHF 130 140 150 160 170 180 MNLNQSAHGD REFGHISTRL RQDRKVVVGH WATASVQQQI DSWCRVAMGW YESQNLKIAR 190 200 210 220 230 240 FGDNMRQVAV TEGDKVSAQI QFGYEVHAYG LGDLQKVVDA VTDEQVAAQI ETYKKDYEVS 250 260 270 280 290 300 PAIFDDEHQF QMLKNEARLE LGMLKFLTDG GFGAFTNCFE NLTGLTNLPG LATQRLMQQG 310 320 330 340 350 360 FGYGGEGDWK TAAMVRIAKV MSKGREGGSS FMEDYTYHFG AVDQVLGAHM LEVCPSIAAA 370 380 390 400 410 420 KPKLEVHLHT IGCRNDIARL IFTGKTGPAL CISVIDMGTR FRMIINEVDT VNPPQELPQL 430 440 450 460 470 480 PVAKALWEPR PNLEIAASAW IHAGGAHHSA YTQGITVDEA VDYAEMAGIE AVVIGADTTV 490 500 RSFKTELRHN AAYYHLKDGV

References

[1]

"Insights into plant cell wall degradation from the genome sequence of the soil bacterium Cellvibrio japonicus." DeBoy R.T., Mongodin E.F., Fouts D.E., Tailford L.E., Khouri H., Emerson J.B., Mohamoud Y., Watkins K., Henrissat B., Gilbert H.J., Nelson K.E. J. Bacteriol. 190:5455-5463(2008) [PubMed: 18556790] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Ueda107.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000934 Genomic DNA. Translation: ACE84530.1.
RefSeq	YP_001983469.1. NC_010995.1.
3D structure databases
ProteinModelPortal	B3PD57.
ModBase	Search...
Protein-protein interaction databases
STRING	B3PD57.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6415862.
GenomeReviews	Gene locus CJA_3015 in contig CP000934_GR.
KEGG	cja:CJA_3015.
PATRIC	21329425. VBICelJap122165_2977.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG297198.
OMA	EVCPTIA.
ProtClustDB	PRK02929.
Enzyme and pathway databases
BioCyc	CJAP155077:CJA_3015-MONOMER.
Family and domain databases
HAMAP	MF_00519. Arabinose_Isome. [Tree]
InterPro	IPR024664. Ara_Isoase_C. IPR004216. Fuc/Ara_isomerase_C. IPR009015. Fucose_isomerase_N/cen. IPR003762. Lara_isomerase. [Graphical view]
KO	K01804.
Pfam	PF11762. Arabinose_Iso_C. 1 hit. PF02610. Arabinose_Isome. 1 hit. [Graphical view]
PIRSF	PIRSF001478. L-ara_isomerase. 1 hit.
ProDom	PD018364. Lara_isomerase. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF50443. Fuc_isomerase_C. 1 hit. SSF53743. Fuc_isomerase_N. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ARAA_CELJU

Accession

Primary (citable) accession number: B3PD57

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	September 2, 2008
Last modified:	January 25, 2012
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program