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Protein

Catalase-peroxidase 1

Gene

katG1

Organism
Cellvibrio japonicus (strain Ueda107) (Pseudomonas fluorescens subsp. cellulosa)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.UniRule annotation

Catalytic activityi

Donor + H2O2 = oxidized donor + 2 H2O.UniRule annotation
2 H2O2 = O2 + 2 H2O.UniRule annotation

Cofactori

heme bUniRule annotationNote: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei95Transition state stabilizerUniRule annotation1
Active sitei99Proton acceptorUniRule annotation1
Metal bindingi267Iron (heme axial ligand)UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase, Peroxidase

Keywords - Biological processi

Hydrogen peroxide

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Catalase-peroxidase 1UniRule annotation (EC:1.11.1.21UniRule annotation)
Short name:
CP 1UniRule annotation
Alternative name(s):
Peroxidase/catalase 1UniRule annotation
Gene namesi
Name:katG1UniRule annotation
Ordered Locus Names:CJA_2891
OrganismiCellvibrio japonicus (strain Ueda107) (Pseudomonas fluorescens subsp. cellulosa)
Taxonomic identifieri498211 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaCellvibrionalesCellvibrionaceaeCellvibrio
Proteomesi
  • UP000001036 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003547551 – 729Catalase-peroxidase 1Add BLAST729

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Cross-linki98 ↔ 226Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-252)UniRule annotation
Cross-linki226 ↔ 252Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-98)UniRule annotation

Post-translational modificationi

The covalent Trp-Tyr-Met adduct is important for the catalase, but not the peroxidase activity of the enzyme.UniRule annotation

Proteomic databases

PRIDEiB3PC77.

Interactioni

Subunit structurei

Homodimer or homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi498211.CJA_2891.

Family & Domainsi

Sequence similaritiesi

Belongs to the peroxidase family. Peroxidase/catalase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C1X. Bacteria.
COG0376. LUCA.
HOGENOMiHOG000218110.
KOiK03782.
OMAiQPEEMML.
OrthoDBiPOG091H05R1.

Family and domain databases

HAMAPiMF_01961. Catal_peroxid. 1 hit.
InterProiIPR000763. Catalase_peroxidase.
IPR010255. Haem_peroxidase.
IPR002016. Haem_peroxidase_pln/fun/bac.
IPR019794. Peroxidases_AS.
[Graphical view]
PfamiPF00141. peroxidase. 2 hits.
[Graphical view]
PRINTSiPR00460. BPEROXIDASE.
PR00458. PEROXIDASE.
SUPFAMiSSF48113. SSF48113. 2 hits.
TIGRFAMsiTIGR00198. cat_per_HPI. 1 hit.
PROSITEiPS00436. PEROXIDASE_2. 1 hit.
PS50873. PEROXIDASE_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3PC77-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDNNPPTSTG KCPFTHGSVT ASGKSNTDWW PNALNLDILH QHDRKTNPLG
60 70 80 90 100
DDFSYAAAFK TLDLQAVKND LKALMTDSQD WWPADWGHYG GLFIRMAWHS
110 120 130 140 150
AGSYRIADGR GGAGTGNQRF APLNSWPDNG NLDKARRLLW PIKKKYGNKL
160 170 180 190 200
SWADLMILAG NMAYESMGLK TFGFGGGRED IWHPEKDVYW GSEKEWLAKS
210 220 230 240 250
GGEGSRYSGE RDLENPLAAV MMGLIYVNPE GVDGNPDPLR TAKDIRETFA
260 270 280 290 300
RMAMNDEETV ALTAGGHTVG KAHGNGNAAN LGPDPEAADV EEQGLGWVNH
310 320 330 340 350
KTRGIGRDTV TSGIEGAWTT HPTKWDNGYF DMLLNHDWEL TKSPAGAWQW
360 370 380 390 400
KPVSIKEEDM PVDVEDPSIR CTPLMTDADM AMKMDPEYRK ISERFYSDPA
410 420 430 440 450
YFSEVFARAW FKLTHRDLGP KARYLGADVP AEDLIWQDPV PTVDYTLSDA
460 470 480 490 500
DIADLKAKIL ASGLSVAELV ATAWDSARTF RGSDFRGGAN GARIRLAPQK
510 520 530 540 550
DWEGNEPARL QKVLGVFAGI QSGLSKKVSI ADLIVVGGAA AVEKAARDAG
560 570 580 590 600
VNITVPFAPG RGDATDAQTD AESFAPLEPV HDGFRNWVKK DYAVQPEEML
610 620 630 640 650
LDRAQLMGLT APEMTVLVGG MRVLGANYGG SKNGVFTDKV GVLSNDFFVN
660 670 680 690 700
LTDMAYQWKP TGKNSYNIVE RNTGTVKWSA TRVDLVFGSN SILRSYAEVY
710 720
AQDDNREKFV RDFVKAWVKV MNADRFDLK
Length:729
Mass (Da):80,327
Last modified:September 2, 2008 - v1
Checksum:i73D3FD614B291706
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000934 Genomic DNA. Translation: ACE86124.1.
RefSeqiWP_012488475.1. NC_010995.1.

Genome annotation databases

EnsemblBacteriaiACE86124; ACE86124; CJA_2891.
KEGGicja:CJA_2891.
PATRICi21329167. VBICelJap122165_2849.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000934 Genomic DNA. Translation: ACE86124.1.
RefSeqiWP_012488475.1. NC_010995.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi498211.CJA_2891.

Proteomic databases

PRIDEiB3PC77.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACE86124; ACE86124; CJA_2891.
KEGGicja:CJA_2891.
PATRICi21329167. VBICelJap122165_2849.

Phylogenomic databases

eggNOGiENOG4105C1X. Bacteria.
COG0376. LUCA.
HOGENOMiHOG000218110.
KOiK03782.
OMAiQPEEMML.
OrthoDBiPOG091H05R1.

Family and domain databases

HAMAPiMF_01961. Catal_peroxid. 1 hit.
InterProiIPR000763. Catalase_peroxidase.
IPR010255. Haem_peroxidase.
IPR002016. Haem_peroxidase_pln/fun/bac.
IPR019794. Peroxidases_AS.
[Graphical view]
PfamiPF00141. peroxidase. 2 hits.
[Graphical view]
PRINTSiPR00460. BPEROXIDASE.
PR00458. PEROXIDASE.
SUPFAMiSSF48113. SSF48113. 2 hits.
TIGRFAMsiTIGR00198. cat_per_HPI. 1 hit.
PROSITEiPS00436. PEROXIDASE_2. 1 hit.
PS50873. PEROXIDASE_4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiKATG1_CELJU
AccessioniPrimary (citable) accession number: B3PC77
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 25, 2008
Last sequence update: September 2, 2008
Last modified: November 2, 2016
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.