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Protein

Delta-like protein

Gene

Dere\GG12134

Organism
Drosophila erecta (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Putative Notch ligand involved in the mediation of Notch signaling.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental proteinUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Delta-like proteinUniRule annotation
Gene namesi
Name:Dere\GG12134Imported
ORF Names:Dere_GG12134Imported, GG12134Imported
OrganismiDrosophila erecta (Fruit fly)Imported
Taxonomic identifieri7220 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000008711 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0104426. Dere\GG12134.

Subcellular locationi

  • Membrane UniRule annotation; Single-pass type I membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei1222 – 1245HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi240 ↔ 249PROSITE-ProRule annotation
Disulfide bondi253 ↔ 265PROSITE-ProRule annotation
Disulfide bondi273 ↔ 282PROSITE-ProRule annotation
Disulfide bondi306 ↔ 315PROSITE-ProRule annotation
Disulfide bondi378 ↔ 387PROSITE-ProRule annotation
Disulfide bondi478 ↔ 487PROSITE-ProRule annotation
Disulfide bondi516 ↔ 525PROSITE-ProRule annotation
Disulfide bondi598 ↔ 607PROSITE-ProRule annotation
Disulfide bondi614 ↔ 624PROSITE-ProRule annotation
Disulfide bondi635 ↔ 644PROSITE-ProRule annotation
Disulfide bondi673 ↔ 682PROSITE-ProRule annotation
Disulfide bondi689 ↔ 699PROSITE-ProRule annotation
Disulfide bondi710 ↔ 719PROSITE-ProRule annotation
Disulfide bondi786 ↔ 795PROSITE-ProRule annotation
Disulfide bondi824 ↔ 833PROSITE-ProRule annotation
Disulfide bondi866 ↔ 875PROSITE-ProRule annotation
Disulfide bondi904 ↔ 913PROSITE-ProRule annotation
Disulfide bondi942 ↔ 951PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini238 – 282DSLInterPro annotationAdd BLAST45
Domaini283 – 316EGF-likeInterPro annotationAdd BLAST34
Domaini350 – 388EGF-likeInterPro annotationAdd BLAST39
Domaini451 – 488EGF-likeInterPro annotationAdd BLAST38
Domaini490 – 526EGF-likeInterPro annotationAdd BLAST37
Domaini570 – 608EGF-likeInterPro annotationAdd BLAST39
Domaini610 – 645EGF-likeInterPro annotationAdd BLAST36
Domaini647 – 683EGF-likeInterPro annotationAdd BLAST37
Domaini685 – 720EGF-likeInterPro annotationAdd BLAST36
Domaini760 – 796EGF-likeInterPro annotationAdd BLAST37
Domaini798 – 834EGF-likeInterPro annotationAdd BLAST37
Domaini836 – 876EGF-likeInterPro annotationAdd BLAST41
Domaini878 – 914EGF-likeInterPro annotationAdd BLAST37
Domaini916 – 952EGF-likeInterPro annotationAdd BLAST37

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotationSAAS annotation, RepeatUniRule annotationSAAS annotation, SignalUniRule annotation, Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

KOiK06052.
OMAiMPGAPDK.
OrthoDBiEOG091G0A88.
PhylomeDBiB3P843.

Family and domain databases

InterProiView protein in InterPro
IPR001774. DSL.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR009030. Growth_fac_rcpt_.
IPR026219. Jagged/Serrate.
IPR011651. Notch_ligand_N.
IPR001007. VWF_dom.
PfamiView protein in Pfam
PF01414. DSL. 1 hit.
PF00008. EGF. 6 hits.
PF07645. EGF_CA. 1 hit.
PF12661. hEGF. 2 hits.
PF07657. MNNL. 1 hit.
PRINTSiPR02059. JAGGEDFAMILY.
SMARTiView protein in SMART
SM00051. DSL. 1 hit.
SM00181. EGF. 14 hits.
SM00179. EGF_CA. 9 hits.
SM00215. VWC_out. 1 hit.
SUPFAMiSSF57184. SSF57184. 1 hit.
PROSITEiView protein in PROSITE
PS00010. ASX_HYDROXYL. 7 hits.
PS51051. DSL. 1 hit.
PS00022. EGF_1. 14 hits.
PS01186. EGF_2. 8 hits.
PS50026. EGF_3. 13 hits.
PS01187. EGF_CA. 5 hits.

Sequencei

Sequence statusi: Complete.

B3P843-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYKMFRKHFR RKPTSSSSAE STIESPDSLG MSKKTATKRQ RPRHREPKIA
60 70 80 90 100
TLPSTVRDCR SLKSACNLIA LILILLVHKI SAAGNFELEI LEISNTNSHL
110 120 130 140 150
LNGYCCGMPA ELRATKTIGC SPCTTAFRLC LKEYQTTEQG ASISTGCSFG
160 170 180 190 200
NATTKILGGS SFVLSDPGVG AIVLPFTFRW TKSFTLILQA LDMYNTSYPD
210 220 230 240 250
AERLIEETSY SGVILPSPEW KTLDHIGRNA RITYRVRVQC AVTYYNTTCT
260 270 280 290 300
TFCRPRDDQF GHYACGSEGQ KLCLNGWQGV NCEEAICKAG CDPVHGKCDR
310 320 330 340 350
PGECECRPGW RGPLCNECMV YPGCKHGSCN GSAWKCVCDT NWGGILCDQD
360 370 380 390 400
LNFCGTHEPC KHGGTCENTA PDKYRCTCAE GLSGEQCEIV EHPCATRPCR
410 420 430 440 450
NGGTCTLKPS NRTQAQVYRT SHGRSNMGRP VRRSSSMRSL DHLRPEGQAL
460 470 480 490 500
NGSSSSGLVS LGSLQLQQQL APDFTCDCAA GWTGPTCEIN IDECAGGPCE
510 520 530 540 550
HGGTCIDLIG GFRCECPPEW HGDVCQVDVN ECEAPHSAGI AANALLTTTA
560 570 580 590 600
TAIIGSNLSS TALLAALTSA VASTSMAIGP CINAKECRNQ PGSFACICKE
610 620 630 640 650
GWGGVTCAEN LDDCVGQCRN GATCIDLVND YRCACAAGFT GRDCETDIDE
660 670 680 690 700
CATSPCRNGG ECVDMVGKFN CICPLGYSGS LCEEAKENCT PSPCLEGHCL
710 720 730 740 750
NTPEGYYCHC PPDRAGKHCE QLRPLCSQPP CNEGCFANVS LATSATTTTT
760 770 780 790 800
STTSATTTRK MAKPSGLPCS GHGSCEMSDV GTFCKCHVGH TGTFCEHNLN
810 820 830 840 850
ECSPNPCRNG GICLDGDGDF TCECMSGWTG KRCSERATGC YAGQCQNGGT
860 870 880 890 900
CMPGAPDKAL QPHCRCTPGW TGLFCAEAID QCRGQPCHNG GTCESGAGWF
910 920 930 940 950
RCVCAQGFSG PDCRINVNEC SPQPCQGGAT CIDGIGGYSC ICPPGRHGLR
960 970 980 990 1000
CEILLSDPKS ACQNASNTIS PYTALNQSQN WLDIALTGRS EDDENCNACV
1010 1020 1030 1040 1050
CENGTSRCTN LWCGLPNCYK LDPLSKSSNL SGVCKQHEVC VPALSETCLS
1060 1070 1080 1090 1100
SPCTVRGDCR ALEPSRRVAP PRLPAKSSCW PNQAVVNENC ARLTILLALE
1110 1120 1130 1140 1150
RVGKGASVEG LCSLVRVLLA AKLIKKPAST LGQDPGMLMV LCDLKTGTND
1160 1170 1180 1190 1200
TVELTVSSSK INDQQLSVAV GLLGELLSSR QLNGVQHRKE LELQHAKLAA
1210 1220 1230 1240 1250
LTSIVEVKLE TARVADGSGH SLLIGVLCGV FIVLVGFSVF ISLYWKQRLA
1260 1270 1280 1290 1300
YRTSSGMNLT PSLDALRHEE EKSNNLQNEE NLRRYTNPLK GSTSSLRAAT
1310 1320 1330 1340 1350
GMELSLNPAP ELAASAASSS ALHRSQPLFP PCDFERELDS STGLKQAHKR
1360 1370 1380 1390 1400
SSQILLHKTQ NSDMRKNTVG SLDSPRKDFG KRSINCKSMP PSSGDEGSDV

LATTVMV
Length:1,407
Mass (Da):150,598
Last modified:September 2, 2008 - v1
Checksum:i5141A523F7153014
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH954182 Genomic DNA. Translation: EDV53447.1.
RefSeqiXP_001981577.1. XM_001981541.2.

Genome annotation databases

EnsemblMetazoaiFBtr0132188; FBpp0130680; FBgn0104426.
GeneIDi6554646.
KEGGider:Dere_GG12134.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH954182 Genomic DNA. Translation: EDV53447.1.
RefSeqiXP_001981577.1. XM_001981541.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0132188; FBpp0130680; FBgn0104426.
GeneIDi6554646.
KEGGider:Dere_GG12134.

Organism-specific databases

FlyBaseiFBgn0104426. Dere\GG12134.

Phylogenomic databases

KOiK06052.
OMAiMPGAPDK.
OrthoDBiEOG091G0A88.
PhylomeDBiB3P843.

Family and domain databases

InterProiView protein in InterPro
IPR001774. DSL.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR009030. Growth_fac_rcpt_.
IPR026219. Jagged/Serrate.
IPR011651. Notch_ligand_N.
IPR001007. VWF_dom.
PfamiView protein in Pfam
PF01414. DSL. 1 hit.
PF00008. EGF. 6 hits.
PF07645. EGF_CA. 1 hit.
PF12661. hEGF. 2 hits.
PF07657. MNNL. 1 hit.
PRINTSiPR02059. JAGGEDFAMILY.
SMARTiView protein in SMART
SM00051. DSL. 1 hit.
SM00181. EGF. 14 hits.
SM00179. EGF_CA. 9 hits.
SM00215. VWC_out. 1 hit.
SUPFAMiSSF57184. SSF57184. 1 hit.
PROSITEiView protein in PROSITE
PS00010. ASX_HYDROXYL. 7 hits.
PS51051. DSL. 1 hit.
PS00022. EGF_1. 14 hits.
PS01186. EGF_2. 8 hits.
PS50026. EGF_3. 13 hits.
PS01187. EGF_CA. 5 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiB3P843_DROER
AccessioniPrimary (citable) accession number: B3P843
Entry historyiIntegrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: February 15, 2017
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.