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B3P2E0

- B3P2E0_DROER

UniProt

B3P2E0 - B3P2E0_DROER

Protein

Histone deacetylase

Gene

Dere\GG10995

Organism
Drosophila erecta (Fruit fly)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 35 (01 Oct 2014)
      Sequence version 1 (02 Sep 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.UniRule annotation

    GO - Molecular functioni

    1. NAD-dependent histone deacetylase activity (H3-K14 specific) Source: UniProtKB-EC
    2. NAD-dependent histone deacetylase activity (H3-K18 specific) Source: UniProtKB-EC
    3. NAD-dependent histone deacetylase activity (H3-K9 specific) Source: UniProtKB-EC
    4. NAD-dependent histone deacetylase activity (H4-K16 specific) Source: UniProtKB-EC

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Chromatin regulatorUniRule annotation, HydrolaseUniRule annotationSAAS annotation

    Keywords - Biological processi

    Transcription, Transcription regulationUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Histone deacetylaseUniRule annotation (EC:3.5.1.98UniRule annotation)
    Gene namesi
    Name:Dere\GG10995Imported
    ORF Names:Dere_GG10995Imported, GG10995Imported
    OrganismiDrosophila erecta (Fruit fly)Imported
    Taxonomic identifieri7220 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
    ProteomesiUP000008711: Unassembled WGS sequence

    Organism-specific databases

    FlyBaseiFBgn0103297. Dere\GG10995.

    Subcellular locationi

    Nucleus UniRule annotation

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    NucleusUniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the histone deacetylase family. HD Type 1 subfamily.UniRule annotation

    Phylogenomic databases

    KOiK11404.
    OrthoDBiEOG7DNNTW.
    PhylomeDBiB3P2E0.

    Family and domain databases

    Gene3Di3.40.800.20. 1 hit.
    InterProiIPR000286. His_deacetylse.
    IPR003084. His_deacetylse_1.
    IPR023801. His_deacetylse_dom.
    [Graphical view]
    PANTHERiPTHR10625. PTHR10625. 1 hit.
    PfamiPF00850. Hist_deacetyl. 1 hit.
    [Graphical view]
    PIRSFiPIRSF037913. His_deacetylse_1. 1 hit.
    PRINTSiPR01270. HDASUPER.
    PR01271. HISDACETLASE.

    Sequencei

    Sequence statusi: Complete.

    B3P2E0-1 [UniParc]FASTAAdd to Basket

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    MTDRRVSYFY NADVGNFHYG AGHPMKPQRL AVTHSLVMNY GLHKKMKIYR    50
    PYKASAQDML RFHSDEYIAY LQQVTPQNIQ CNSVAYTKYL AHFSVGEDCP 100
    VFDGLFDFCA MYTGASLEGA QKLNHNHSDI CINWSGGLHH AKKFEASGFC 150
    YVNDIVIGIL ELLKYHPRVL YIDIDVHHGD GVQEAFYLTD RVMTASFHKY 200
    GNYFFPGTGD MYEIGAESGR YYSVNVPLKE GIDDQSYFQV FKPIISAIMD 250
    FYRPTAIVLQ CGADSLAGDR LGCFSLSTKG HGECVKFVKE LNVPTLVVGG 300
    GGYTLRNVAR CWTHETSLLV DQDIENDLPA TEYYDFFAPD FTLHPEINSR 350
    QDNANSKQYL ELIVKHVYEN LKMCQHSPSV QMVQTPPDVD LEELRNNREE 400
    ASDPDVRMSV ADEDKIVDAK NEFYDGDQDQ DKPDSAES 438
    Length:438
    Mass (Da):49,688
    Last modified:September 2, 2008 - v1
    Checksum:iEAE7D8A0687DB8B7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH954181 Genomic DNA. Translation: EDV47890.1.
    RefSeqiXP_001978932.1. XM_001978896.1.

    Genome annotation databases

    EnsemblMetazoaiFBtr0131049; FBpp0129541; FBgn0103297.
    GeneIDi6552202.
    KEGGider:Dere_GG10995.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH954181 Genomic DNA. Translation: EDV47890.1 .
    RefSeqi XP_001978932.1. XM_001978896.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai FBtr0131049 ; FBpp0129541 ; FBgn0103297 .
    GeneIDi 6552202.
    KEGGi der:Dere_GG10995.

    Organism-specific databases

    FlyBasei FBgn0103297. Dere\GG10995.

    Phylogenomic databases

    KOi K11404.
    OrthoDBi EOG7DNNTW.
    PhylomeDBi B3P2E0.

    Family and domain databases

    Gene3Di 3.40.800.20. 1 hit.
    InterProi IPR000286. His_deacetylse.
    IPR003084. His_deacetylse_1.
    IPR023801. His_deacetylse_dom.
    [Graphical view ]
    PANTHERi PTHR10625. PTHR10625. 1 hit.
    Pfami PF00850. Hist_deacetyl. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF037913. His_deacetylse_1. 1 hit.
    PRINTSi PR01270. HDASUPER.
    PR01271. HISDACETLASE.
    ProtoNeti Search...

    Publicationsi

    1. "Evolution of genes and genomes on the Drosophila phylogeny."
      Drosophila 12 genomes consortium
      Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Tucson 14021-0224.01Imported.

    Entry informationi

    Entry nameiB3P2E0_DROER
    AccessioniPrimary (citable) accession number: B3P2E0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 2, 2008
    Last sequence update: September 2, 2008
    Last modified: October 1, 2014
    This is version 35 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3