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B3P1B6

- B3P1B6_DROER

UniProt

B3P1B6 - B3P1B6_DROER

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Protein
DNA ligase
Gene
Dere\GG17130, Dere_GG17130, GG17130
Organism
Drosophila erecta (Fruit fly)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: UniProtKB-KW
  3. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Name:Dere\GG17130Imported
ORF Names:Dere_GG17130Imported, GG17130Imported
OrganismiDrosophila erecta (Fruit fly)
Taxonomic identifieri7220 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000008711: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0109358. Dere\GG17130.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

KOiK10776.
OrthoDBiEOG7BKCT2.
PhylomeDBiB3P1B6.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 1 hit.
PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3P1B6-1 [UniParc]FASTAAdd to Basket

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MLLPRLTWQT RFLTRLACNK MASKGLRNED NKFDTFRRIC DEIAGESSYL    50
KKAEKLQRFF EKGSSGKGFK GDTLLWVQFL IPEANQRVYN LQNKALIKLF 100
SRILNANQQQ MHLDLEQDGD VSETLRKHFA ASRKLKPQVQ SKLYLQEVEQ 150
LLLKLVERTK EDEQTELLHE LCSKATDLDL RTFIRLVKHD LRINARARHI 200
LDAFGSEAYP AYQSSRDLVA IVGQFAGKDN KKDAHSPIKK ANKTNSSAIQ 250
VMTPISPMLA SPCKSVEEAF KKSPTGLYSE IKYDGERVQI HKQGNEFKFF 300
SRNLKPVVDH KIRALKEYIP QAFPGGGEMI LDSEIILVDT DTGALLPFGS 350
LGAHKKQTFA NAAVCLFVFD CILYDGEDLT QLPFRKRREI LEQNIQPIKS 400
HVQLSESEFL KTTKELAVMT ARVLHANLEG VVLKSPTSTY QPGKRNWLKV 450
KKDYLFDGKM ADTADLVVLG AWYGSGKKGG TLSIFLMGCY DAFGRLWKTV 500
TKVHSGLDDA TNAEVHESLI KLTERADANA IPSWLLCSKS LVPDVLAKDP 550
LKMPVWEITG AEFTKSDAHT ASGISIRFPR ITRRRSDKSA KEANDLAHLE 600
DIFEASKTNV NVDLLLANCS KDEKAIDIKT SPQKEKKLNG NRSSSTKKLK 650
RRKTSTDDED EAPALSKHKE AKAIRSLSPS QKGLKDFFKP SKELKSVVKK 700
EPKQTENATE PTSSKGKLFE GLVAYFAMEK DSSKLMQQFS QHGGSCTTEP 750
RKANLVFYNT NEASDMEKLR RLYRRSCRHL NVSWLQNSLD TQSRQPYPLY 800
AVMMK 805
Length:805
Mass (Da):91,029
Last modified:September 2, 2008 - v1
Checksum:i7335881521A600D9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH954181 Genomic DNA. Translation: EDV49375.1.
RefSeqiXP_001980417.1. XM_001980381.1.

Genome annotation databases

EnsemblMetazoaiFBtr0137184; FBpp0135676; FBgn0109358.
GeneIDi6553675.
KEGGider:Dere_GG17130.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH954181 Genomic DNA. Translation: EDV49375.1 .
RefSeqi XP_001980417.1. XM_001980381.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0137184 ; FBpp0135676 ; FBgn0109358 .
GeneIDi 6553675.
KEGGi der:Dere_GG17130.

Organism-specific databases

FlyBasei FBgn0109358. Dere\GG17130.

Phylogenomic databases

KOi K10776.
OrthoDBi EOG7BKCT2.
PhylomeDBi B3P1B6.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProi IPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SMARTi SM00292. BRCT. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS50172. BRCT. 1 hit.
PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 14021-0224.01.

Entry informationi

Entry nameiB3P1B6_DROER
AccessioniPrimary (citable) accession number: B3P1B6
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: June 11, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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