Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

DNA ligase

Gene

Dere\GG17130

Organism
Drosophila erecta (Fruit fly)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n)-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) + AMP + diphosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseUniRule annotation
Biological processDNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Name:Dere\GG17130Imported
ORF Names:Dere_GG17130Imported, GG17130Imported
OrganismiDrosophila erecta (Fruit fly)Imported
Taxonomic identifieri7220 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000008711 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0109358 Dere\GG17130

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini357 – 491DNA_LIGASE_A3InterPro annotationAdd BLAST135
Domaini714 – 802BRCTInterPro annotationAdd BLAST89

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

KOiK10776
OMAiDCIYFND
OrthoDBiEOG091G0XBU
PhylomeDBiB3P1B6

Family and domain databases

Gene3Di1.10.3260.10, 1 hit
3.40.50.10190, 1 hit
InterProiView protein in InterPro
IPR001357 BRCT_dom
IPR036420 BRCT_dom_sf
IPR000977 DNA_ligase_ATP-dep
IPR012309 DNA_ligase_ATP-dep_C
IPR012310 DNA_ligase_ATP-dep_cent
IPR016059 DNA_ligase_ATP-dep_CS
IPR012308 DNA_ligase_ATP-dep_N
IPR036599 DNA_ligase_N_sf
IPR012340 NA-bd_OB-fold
PfamiView protein in Pfam
PF04679 DNA_ligase_A_C, 1 hit
PF01068 DNA_ligase_A_M, 1 hit
PF04675 DNA_ligase_A_N, 1 hit
SUPFAMiSSF117018 SSF117018, 1 hit
SSF50249 SSF50249, 1 hit
SSF52113 SSF52113, 1 hit
TIGRFAMsiTIGR00574 dnl1, 1 hit
PROSITEiView protein in PROSITE
PS50172 BRCT, 1 hit
PS00697 DNA_LIGASE_A1, 1 hit
PS00333 DNA_LIGASE_A2, 1 hit
PS50160 DNA_LIGASE_A3, 1 hit

Sequencei

Sequence statusi: Complete.

B3P1B6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLPRLTWQT RFLTRLACNK MASKGLRNED NKFDTFRRIC DEIAGESSYL
60 70 80 90 100
KKAEKLQRFF EKGSSGKGFK GDTLLWVQFL IPEANQRVYN LQNKALIKLF
110 120 130 140 150
SRILNANQQQ MHLDLEQDGD VSETLRKHFA ASRKLKPQVQ SKLYLQEVEQ
160 170 180 190 200
LLLKLVERTK EDEQTELLHE LCSKATDLDL RTFIRLVKHD LRINARARHI
210 220 230 240 250
LDAFGSEAYP AYQSSRDLVA IVGQFAGKDN KKDAHSPIKK ANKTNSSAIQ
260 270 280 290 300
VMTPISPMLA SPCKSVEEAF KKSPTGLYSE IKYDGERVQI HKQGNEFKFF
310 320 330 340 350
SRNLKPVVDH KIRALKEYIP QAFPGGGEMI LDSEIILVDT DTGALLPFGS
360 370 380 390 400
LGAHKKQTFA NAAVCLFVFD CILYDGEDLT QLPFRKRREI LEQNIQPIKS
410 420 430 440 450
HVQLSESEFL KTTKELAVMT ARVLHANLEG VVLKSPTSTY QPGKRNWLKV
460 470 480 490 500
KKDYLFDGKM ADTADLVVLG AWYGSGKKGG TLSIFLMGCY DAFGRLWKTV
510 520 530 540 550
TKVHSGLDDA TNAEVHESLI KLTERADANA IPSWLLCSKS LVPDVLAKDP
560 570 580 590 600
LKMPVWEITG AEFTKSDAHT ASGISIRFPR ITRRRSDKSA KEANDLAHLE
610 620 630 640 650
DIFEASKTNV NVDLLLANCS KDEKAIDIKT SPQKEKKLNG NRSSSTKKLK
660 670 680 690 700
RRKTSTDDED EAPALSKHKE AKAIRSLSPS QKGLKDFFKP SKELKSVVKK
710 720 730 740 750
EPKQTENATE PTSSKGKLFE GLVAYFAMEK DSSKLMQQFS QHGGSCTTEP
760 770 780 790 800
RKANLVFYNT NEASDMEKLR RLYRRSCRHL NVSWLQNSLD TQSRQPYPLY

AVMMK
Length:805
Mass (Da):91,029
Last modified:September 2, 2008 - v1
Checksum:i7335881521A600D9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH954181 Genomic DNA Translation: EDV49375.1
RefSeqiXP_001980417.1, XM_001980381.2

Genome annotation databases

EnsemblMetazoaiFBtr0137184; FBpp0135676; FBgn0109358
GeneIDi6553675
KEGGider:Dere_GG17130

Similar proteinsi

Entry informationi

Entry nameiB3P1B6_DROER
AccessioniPrimary (citable) accession number: B3P1B6
Entry historyiIntegrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: March 28, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health