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Protein

Histone-lysine N-methyltransferase

Gene

Dere\GG17783

Organism
Drosophila erecta (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotation, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone-lysine N-methyltransferaseSAAS annotation (EC:2.1.1.43SAAS annotation)
Gene namesi
Name:Dere\GG17783Imported
ORF Names:Dere_GG17783Imported, GG17783Imported
OrganismiDrosophila erecta (Fruit fly)Imported
Taxonomic identifieri7220 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000008711 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0110005. Dere\GG17783.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Family & Domainsi

Sequence similaritiesi

Contains 1 post-SET domain.UniRule annotation

Phylogenomic databases

KOiK11423.
OrthoDBiEOG7DFXBB.
PhylomeDBiB3NWN5.

Family and domain databases

InterProiIPR017956. AT_hook_DNA-bd_motif.
IPR006560. AWS_dom.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR013257. SRI.
IPR001202. WW_dom.
[Graphical view]
PfamiPF02178. AT_hook. 2 hits.
PF00856. SET. 1 hit.
PF08236. SRI. 1 hit.
PF00397. WW. 1 hit.
[Graphical view]
SMARTiSM00384. AT_hook. 2 hits.
SM00570. AWS. 1 hit.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
SM00456. WW. 1 hit.
[Graphical view]
SUPFAMiSSF51045. SSF51045. 1 hit.
PROSITEiPS51215. AWS. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
PS01159. WW_DOMAIN_1. 1 hit.
PS50020. WW_DOMAIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3NWN5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEESGPPSNP SAVASRGRGR GRPPKVAPTA VGHALKHSSL AIKNADAVAS
60 70 80 90 100
PTPPEDQDSG QSECRRSSRK KIIKFDVRDL LNKNRKAHKI QIEARIDSNP
110 120 130 140 150
SPGQSSGTTG ASTCTSMSAA SAASASSAAS VSRLFSMFEM SHPSLPPPPP
160 170 180 190 200
PPALEIFAKP RPTQSLIVAQ VTSEPSAAGG AHPVQTWVSL PAVTPRKRGR
210 220 230 240 250
PRKSQSADVA IVPTVIAPSC FDSDTNSTST TTSNMSSDSG EPAGFPKRKP
260 270 280 290 300
KSKLRVSLKR LNLSRRQESS DSGNSPSSSS PEVEPPALQD ENALDQQPDQ
310 320 330 340 350
EQNLTRIVAA EDNSDSDSQI MFIEIETESP KGQEEHEEQE EEQPVEVEPE
360 370 380 390 400
ELIDIDMELA KQGPTPDPEQ DLDEIMVEVL SGPPSLWSAD DEAEEEEDVT
410 420 430 440 450
VQRATPPEDE PTADSSSPAP RRSRRSAPLS GSSRQGKTLE ETFAEIAAES
460 470 480 490 500
SKQILEAEES QDPEEQHILI DLIEDTLSEP EVTSSVSPII EHIEVEEIVV
510 520 530 540 550
EDNQLLEEVD SKQELYINVA LEVSETKAVA SEPEQEFSES DKIVATLIAV
560 570 580 590 600
IPEPKVETKA TLNEELAIDV VPKPQLFAED VPIAQGIAET AVAVEQLHEK
610 620 630 640 650
TTIETKPPTE IIIAETKPSL VVKETPPKYE ADQKATQEDL PESKPAETIP
660 670 680 690 700
AFERIPHIEE ESIAAPLLLS ESDTRDKAIG EVLADQTSLS TVEKSNKKVE
710 720 730 740 750
KTEFPTEITA LNAETVQEDR PLAVPAEETR NNSSDEPKSL ENSERNQERE
760 770 780 790 800
DSEVAVVEIK ERNNQVEQEK TPIPEMKERK KPLRKGDKEV GKSTKENALE
810 820 830 840 850
KNMESKKSCP DGTPGKQKET GKAAKEATMK KEAEKEKASA SLSMDALDTS
860 870 880 890 900
SADFTPKRDK DTAQCPPLLH NSERSSTKPL QESALSEISK STSNEGAVAA
910 920 930 940 950
PDASKEEQAG KKPLTDKKLA TGFVECDAMF KAMDMANAQM RLEEKSKKKL
960 970 980 990 1000
KKVPPKAEAP SLLPTAKPVP GQKKSLAGKA SSRRNTVYED SPKQDRNSSP
1010 1020 1030 1040 1050
SSDSAQVNTS AGKLKRSRAK KKPNPRRSTI CEDAKDLRSS TSSTPTEEVA
1060 1070 1080 1090 1100
ASSPVSTSSD SSSKRNAPKG TSHELAGGSK LDQRRNTICE DRQAEIALPV
1110 1120 1130 1140 1150
PLTKRRFSMH PKASANPLHD TLLRTSGKKR ARKGGKESLS RQSSLDSSSS
1160 1170 1180 1190 1200
ASQGASKKKA QKSAEALNAA LLETESSEST SSGSKMRRWD VQTSPDLDPL
1210 1220 1230 1240 1250
SDIAKFIEDG VNLLKRDYKV DEDQREKGQD EVKREANPEE DEFAQRLANM
1260 1270 1280 1290 1300
ETPATTPSPS PTQSNPEDSA TPATILQESN AGGGVRRSHR IKQKPQGQRA
1310 1320 1330 1340 1350
SQGRGVASMA LAPISMDEQL TELANIEAIN EQFLRGEGLN TFQLLKENYY
1360 1370 1380 1390 1400
RCARQVSQEN AEMQCDCFLT GDEEAQGHLS CGAGCINRML MIECGPLCTN
1410 1420 1430 1440 1450
GARCTNKRFQ QHQCWPCRVF RTEKKGCGIT AELQIPPGEF IMEYVGEVID
1460 1470 1480 1490 1500
SEEFERRQHL YSKDRNRHYY FMALRGEAII DATSKGNISR YINHSCDPNA
1510 1520 1530 1540 1550
ETQKWTVNGE LRIGFFSVKP IQPGEEITFD YQYQRYGRDA QRCYCEAANC
1560 1570 1580 1590 1600
RGWIGGEPDS DEGEQLDVES DSEADLDEEE LEAEPEAEAE AEGGQPRKTS
1610 1620 1630 1640 1650
KAKSKSKIKA KLPLATSRKR KEQTKPKDRE YKAGRWLKPS SGGPSSAEKG
1660 1670 1680 1690 1700
SRKPKVNKFH AMLEDPDVLE ELSLLSRSGL KNQLDTLRFS RCMVRAKLLQ
1710 1720 1730 1740 1750
TRLQLLGVLT RGELPCRRLF LDYHGLRLLH AWISENGNDE QLRVALLDTL
1760 1770 1780 1790 1800
ESLPIPNRTM LNDSRVYQSV QLWSNGLEQQ KAAAPHATQA ALHKRMVALL
1810 1820 1830 1840 1850
QKWQALPEIF RIPKRERIEQ MKEHEREADR QQKHVHASTA LEDQRERESS
1860 1870 1880 1890 1900
SDRFRQDRFR RDTTSSRISK PIRMSGNNTI CTITTQQKGS NGAMDGMARN
1910 1920 1930 1940 1950
DSRRRSDMGP STEPRRTLSK ELRRSLFERK VALDEAERRV CSEDWREHEL
1960 1970 1980 1990 2000
RCEFFGADLN TDPKQLPFYQ NADTGEWFNS DDMLVPAPPR TELLSQALLS
2010 2020 2030 2040 2050
PEIDGGQAAP AVEYKLPAGV DPLPPAWHWR MTSDGDIYYY NLRERISQWE
2060 2070 2080 2090 2100
PPSPEQRLQT LLEEDPTQQP LHELQNDPAL LANELIQVDI DYVGSLSSKS
2110 2120 2130 2140 2150
LAQYVETKVR ERRDLRRSRL VSIRLISPRR DEDRLYNQLE SRKYKENKEK
2160 2170 2180 2190 2200
IRRRKELYRR RKLDAPPDIS ANAEDAIPGK PLPIQAYLYS SDEDETEVPV
2210 2220 2230 2240 2250
GEPAATEGTV APEEDQESLN LAPSTSHAAM AALGKSVAQA TQPSVVGAVV
2260 2270 2280 2290 2300
KRKLPMPPNV SAKKHRQEQR SKKGPSSQSL LTTTSGREAH EKFRFEISGH
2310 2320 2330 2340 2350
VADFLRPYRK ESCQLGRITS DEDYKFLIKR LSHHITTKEV RYCDITGNPL
2360 2370 2380
SCTESVKHKS YDFINQYMRK KGRVYRKPAE DTMF
Length:2,384
Mass (Da):264,836
Last modified:September 2, 2008 - v1
Checksum:i9E41332D068D787C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH954180 Genomic DNA. Translation: EDV47197.1.
RefSeqiXP_001978270.1. XM_001978234.1.

Genome annotation databases

EnsemblMetazoaiFBtr0137837; FBpp0136329; FBgn0110005.
GeneIDi6551019.
KEGGider:Dere_GG17783.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH954180 Genomic DNA. Translation: EDV47197.1.
RefSeqiXP_001978270.1. XM_001978234.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0137837; FBpp0136329; FBgn0110005.
GeneIDi6551019.
KEGGider:Dere_GG17783.

Organism-specific databases

FlyBaseiFBgn0110005. Dere\GG17783.

Phylogenomic databases

KOiK11423.
OrthoDBiEOG7DFXBB.
PhylomeDBiB3NWN5.

Family and domain databases

InterProiIPR017956. AT_hook_DNA-bd_motif.
IPR006560. AWS_dom.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR013257. SRI.
IPR001202. WW_dom.
[Graphical view]
PfamiPF02178. AT_hook. 2 hits.
PF00856. SET. 1 hit.
PF08236. SRI. 1 hit.
PF00397. WW. 1 hit.
[Graphical view]
SMARTiSM00384. AT_hook. 2 hits.
SM00570. AWS. 1 hit.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
SM00456. WW. 1 hit.
[Graphical view]
SUPFAMiSSF51045. SSF51045. 1 hit.
PROSITEiPS51215. AWS. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
PS01159. WW_DOMAIN_1. 1 hit.
PS50020. WW_DOMAIN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 14021-0224.01Imported.

Entry informationi

Entry nameiB3NWN5_DROER
AccessioniPrimary (citable) accession number: B3NWN5
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: March 4, 2015
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.