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Protein

Hexokinase

Gene

Dere\GG18317

Organism
Drosophila erecta (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
Name:Dere\GG18317Imported
ORF Names:Dere_GG18317Imported, GG18317Imported
OrganismiDrosophila erecta (Fruit fly)Imported
Taxonomic identifieri7220 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000008711 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0110533. Dere\GG18317.

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

KOiK00844.
OrthoDBiEOG7S21X5.
PhylomeDBiB3NT59.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 1 hit.
PS51748. HEXOKINASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3NT59-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDRELNGAMR SVSINSAQLN GHNNGGGLDE TDRVGVAQGA ALSATEKLTT
60 70 80 90 100
TTAAATKSTT AATNATTATT TNLATHSPQQ IALLSAAEKS KMVHELCQQL
110 120 130 140 150
LLTDEQVEEL CYRILHELRR GLAKDTHPKA NVKCFVTYVQ DLPNGNERGK
160 170 180 190 200
FLALDLGGTN FRVLLIHLQE NNDFQMESRI YAIPQHIMIG SGTQLFDHIA
210 220 230 240 250
ECLSNFMAEH NVYKERLPLG FTFSFPLRQL GLTKGLLETW TKGFNCAGVV
260 270 280 290 300
NEDVVQLLKD AIARRGDVQI DVCAILNDTT GTLMSCAWKN HNCKIGLIVG
310 320 330 340 350
TGANACYMER VEEAELFAAE DPRKKHVLIN TEWGAFGDNG ALDFVRTEFD
360 370 380 390 400
RDIDVHSINP GKQTFEKMIS GMYMGELVRL VLVKMTQAGI LFNGQDSEVL
410 420 430 440 450
NTRGLFFTKY VSEIEADEPG NFTNCRLVLE ELGLTNATDG DCANVRYICE
460 470 480 490 500
CVSKRAAHLV SAGIATLINK MDEPTVTVGV DGSVYRFHPK FHNLMVEKIS
510 520 530
QLIKPGITFD LMLSEDGSGR GAALVAAVAC REDILNGKK
Length:539
Mass (Da):59,055
Last modified:September 2, 2008 - v1
Checksum:i29EA4E28D9E821BA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH954180 Genomic DNA. Translation: EDV46239.1.
RefSeqiXP_001977312.1. XM_001977276.1.

Genome annotation databases

EnsemblMetazoaiFBtr0138371; FBpp0136863; FBgn0110533.
GeneIDi6549781.
KEGGider:Dere_GG18317.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH954180 Genomic DNA. Translation: EDV46239.1.
RefSeqiXP_001977312.1. XM_001977276.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0138371; FBpp0136863; FBgn0110533.
GeneIDi6549781.
KEGGider:Dere_GG18317.

Organism-specific databases

FlyBaseiFBgn0110533. Dere\GG18317.

Phylogenomic databases

KOiK00844.
OrthoDBiEOG7S21X5.
PhylomeDBiB3NT59.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 1 hit.
PS51748. HEXOKINASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 14021-0224.01Imported.

Entry informationi

Entry nameiB3NT59_DROER
AccessioniPrimary (citable) accession number: B3NT59
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: June 24, 2015
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.