Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Histone-lysine N-methyltransferase

Gene

Dere\GG19893

Organism
Drosophila erecta (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. histone-lysine N-methyltransferase activity Source: UniProtKB-EC
  3. zinc ion binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotation, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone-lysine N-methyltransferaseSAAS annotation (EC:2.1.1.43SAAS annotation)
Gene namesi
Name:Dere\GG19893Imported
ORF Names:Dere_GG19893Imported, GG19893Imported
OrganismiDrosophila erecta (Fruit fly)Imported
Taxonomic identifieri7220 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000008711 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0112094. Dere\GG19893.

Subcellular locationi

  1. Nucleus UniRule annotation

GO - Cellular componenti

  1. chromosome Source: UniProtKB-KW
  2. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

ChromosomeSAAS annotation, NucleusUniRule annotationSAAS annotation

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains 1 post-SET domain.UniRule annotation
Contains 1 pre-SET domain.UniRule annotation

Phylogenomic databases

KOiK11421.
OrthoDBiEOG7ZD1TG.
PhylomeDBiB3NQY4.

Family and domain databases

Gene3Di3.30.890.10. 1 hit.
InterProiIPR016177. DNA-bd_dom.
IPR001739. Methyl_CpG_DNA-bd.
IPR003616. Post-SET_dom.
IPR007728. Pre-SET_dom.
IPR001214. SET_dom.
[Graphical view]
PfamiPF01429. MBD. 1 hit.
PF05033. Pre-SET. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00317. SET. 1 hit.
[Graphical view]
SUPFAMiSSF54171. SSF54171. 1 hit.
PROSITEiPS50982. MBD. 1 hit.
PS50868. POST_SET. 1 hit.
PS50867. PRE_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3NQY4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHYALYNSCP VAHKHLPPLD IEPSVGDYVH HVPPAGEIVR PPIQLGETYY
60 70 80 90 100
AVKNKAIASW VSIKVIEFTE STAINGNTMK SYKIRYLNTP YQMIKTVTAK
110 120 130 140 150
HIAYFEPPPV RLTIGTRVIA YFDGTTLSRG KDKGVVQSAF YPGIIAEPLK
160 170 180 190 200
QANRYRYLIF YDDGYTQYVP HRDVRLVCQA SEKVWEDVHA ASRDFIQKYV
210 220 230 240 250
EKYSVDRPMV QCTRGQSMNT ESNGTWLYAR VIDIDCSLVL MQFEGDKNHT
260 270 280 290 300
EWIYRGSLRL GPVFRETQNT MNSSSAQQMR VPRRTEPFIR YTKEMESSSK
310 320 330 340 350
VNQQMRAFAR KSSASGQNVA LAAAASSSAT SGGGRTNVGG ASTSNSASAV
360 370 380 390 400
RHLNNSTIYV DDENRPKGHV VYFTAKRNLP PKMYKCHECS PNCLFKIVHR
410 420 430 440 450
LDSYSPLAKP LLSGWERLVM RQKTKKSVVY KGPCGKSLRN LAEVHRYLRA
460 470 480 490 500
TENVLNVDNF DFTPDLKCLA EYSIDPSIVK DTDISRGQEK MAIPLVNYYD
510 520 530 540 550
NTLPPPCTYA KQRIPTEGVH LNLDEEFLLC CDCEDDCSDK SKCACWQLTV
560 570 580 590 600
AGVRYCNPKK PIEEIGYQYK RLHEHVPTGI YECNSRCKCK KNCLNRVVQF
610 620 630 640 650
SLEMKLQVFK TSNRGWGLRC VNDIPKGAFI CIYAGHLLTE TMANEGGQDA
660 670 680 690 700
GDEYFADLDY IEVAEQLKEG YESEVDHSDP DAEEDNGGPD AEDDDDFRPN
710 720 730 740 750
YHYQRKIKRT SRSNSTQSSE LDSQERAVIN FNPNADLDET VRENSVRRLF
760 770 780 790 800
GKDEAPYIMD AKTTGNLGRY FNHSCNPNLF VQNVFVDTHD LRFPWVAFFS
810 820 830 840
AAHIRSGTEL TWNYNYEVGV VPGKVLYCQC GAPNCRIRLL
Length:840
Mass (Da):95,347
Last modified:September 2, 2008 - v1
Checksum:iCA3C6AF2EF4093F5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH954179 Genomic DNA. Translation: EDV57067.1.
RefSeqiXP_001976667.1. XM_001976631.1.

Genome annotation databases

EnsemblMetazoaiFBtr0139947; FBpp0138439; FBgn0112094.
GeneIDi6548401.
KEGGider:Dere_GG19893.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH954179 Genomic DNA. Translation: EDV57067.1.
RefSeqiXP_001976667.1. XM_001976631.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0139947; FBpp0138439; FBgn0112094.
GeneIDi6548401.
KEGGider:Dere_GG19893.

Organism-specific databases

FlyBaseiFBgn0112094. Dere\GG19893.

Phylogenomic databases

KOiK11421.
OrthoDBiEOG7ZD1TG.
PhylomeDBiB3NQY4.

Family and domain databases

Gene3Di3.30.890.10. 1 hit.
InterProiIPR016177. DNA-bd_dom.
IPR001739. Methyl_CpG_DNA-bd.
IPR003616. Post-SET_dom.
IPR007728. Pre-SET_dom.
IPR001214. SET_dom.
[Graphical view]
PfamiPF01429. MBD. 1 hit.
PF05033. Pre-SET. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00317. SET. 1 hit.
[Graphical view]
SUPFAMiSSF54171. SSF54171. 1 hit.
PROSITEiPS50982. MBD. 1 hit.
PS50868. POST_SET. 1 hit.
PS50867. PRE_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 14021-0224.01Imported.

Entry informationi

Entry nameiB3NQY4_DROER
AccessioniPrimary (citable) accession number: B3NQY4
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: March 4, 2015
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.