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Protein

Alkaline phosphatase

Gene

Dere\GG20710

Organism
Drosophila erecta (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.UniRule annotation

GO - Molecular functioni

  1. alkaline phosphatase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Alkaline phosphataseUniRule annotation (EC:3.1.3.1UniRule annotation)
Gene namesi
Name:Dere\GG20710Imported
ORF Names:Dere_GG20710Imported, GG20710Imported
OrganismiDrosophila erecta (Fruit fly)Imported
Taxonomic identifieri7220 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000008711: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0112897. Dere\GG20710.

PTM / Processingi

Keywords - PTMi

PhosphoproteinUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB3NNE8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alkaline phosphatase family.UniRule annotation

Phylogenomic databases

KOiK01077.
OrthoDBiEOG7SN8CH.
PhylomeDBiB3NNE8.

Family and domain databases

Gene3Di3.40.720.10. 1 hit.
InterProiIPR017849. Alkaline_Pase-like_a/b/a.
IPR001952. Alkaline_phosphatase.
IPR018299. Alkaline_phosphatase_AS.
IPR017850. Alkaline_phosphatase_core.
[Graphical view]
PfamiPF00245. Alk_phosphatase. 1 hit.
[Graphical view]
PRINTSiPR00113. ALKPHPHTASE.
SMARTiSM00098. alkPPc. 1 hit.
[Graphical view]
SUPFAMiSSF53649. SSF53649. 1 hit.
PROSITEiPS00123. ALKALINE_PHOSPHATASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3NNE8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHSSQRQWLH PILLFLLASV GTALSRVQEV HNVLELTGQK ANQLRFGTDI
60 70 80 90 100
ATGKYTPPEE MDPQFWYKLA DEEIARRLLL PQPNSIKAKN VIMFLGDGMP
110 120 130 140 150
LSTVTAARIL KGQRQNKTGE ESSLSFEKFP YSGLSRTYCA NAQVPDSACT
160 170 180 190 200
ATAYLCGVKT NIINIGVSAA VNFNNCTASQ DPANRLTSIA EWSQNAGKST
210 220 230 240 250
GFVTTTTLTH ASPSGAYAKT ANRMWQSDTD VTSYGVDAST CVDMATQLVT
260 270 280 290 300
QTPGKNFEVM FGGGMGKFLP KTMKDSHGKA GERSDGVNLL SRWQGLHDKG
310 320 330 340 350
VLVTNRKQLL NLDVSTASSI IGTFQSGLMD FHMDADPTYQ PTLSELTEVA
360 370 380 390 400
IKKLSHNKNG YFVFIEGGLI DYGNHYTQPG YALDEALEFE KAIQLARDMT
410 420 430 440 450
NISETLIVVT ADHGHAVSIA GYPGRGTPIL GINQHDTDIN GVKYSVLNYA
460 470 480 490 500
AGPNQYLDEN GQRIPLDDIL GPDDAIAPSY IAKEIGVHSG EDVGIWASGP
510 520 530
QSHLFTGVMQ QSTIPHLMAY ASCVGSGKQV CDNSQRKA
Length:538
Mass (Da):58,284
Last modified:September 2, 2008 - v1
Checksum:iA70C6CEF74BB672C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH954179 Genomic DNA. Translation: EDV55572.1.
RefSeqiXP_001975172.1. XM_001975136.1.

Genome annotation databases

EnsemblMetazoaiFBtr0140764; FBpp0139256; FBgn0112897.
GeneIDi6548081.
KEGGider:Dere_GG20710.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH954179 Genomic DNA. Translation: EDV55572.1.
RefSeqiXP_001975172.1. XM_001975136.1.

3D structure databases

ProteinModelPortaliB3NNE8.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0140764; FBpp0139256; FBgn0112897.
GeneIDi6548081.
KEGGider:Dere_GG20710.

Organism-specific databases

FlyBaseiFBgn0112897. Dere\GG20710.

Phylogenomic databases

KOiK01077.
OrthoDBiEOG7SN8CH.
PhylomeDBiB3NNE8.

Family and domain databases

Gene3Di3.40.720.10. 1 hit.
InterProiIPR017849. Alkaline_Pase-like_a/b/a.
IPR001952. Alkaline_phosphatase.
IPR018299. Alkaline_phosphatase_AS.
IPR017850. Alkaline_phosphatase_core.
[Graphical view]
PfamiPF00245. Alk_phosphatase. 1 hit.
[Graphical view]
PRINTSiPR00113. ALKPHPHTASE.
SMARTiSM00098. alkPPc. 1 hit.
[Graphical view]
SUPFAMiSSF53649. SSF53649. 1 hit.
PROSITEiPS00123. ALKALINE_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 14021-0224.01Imported.

Entry informationi

Entry nameiB3NNE8_DROER
AccessioniPrimary (citable) accession number: B3NNE8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: January 7, 2015
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.