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Protein

Aldose 1-epimerase

Gene

Dere\GG14088

Organism
Drosophila erecta (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Converts alpha-aldose to the beta-anomer.UniRule annotation

Catalytic activityi

Alpha-D-glucose = beta-D-glucose.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. aldose 1-epimerase activity Source: UniProtKB-EC
  2. carbohydrate binding Source: InterPro

GO - Biological processi

  1. hexose metabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolismUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00242.

Names & Taxonomyi

Protein namesi
Recommended name:
Aldose 1-epimeraseUniRule annotation (EC:5.1.3.3UniRule annotation)
Alternative name(s):
Galactose mutarotaseUniRule annotation
Gene namesi
Name:Dere\GG14088Imported
ORF Names:Dere_GG14088Imported, GG14088Imported
OrganismiDrosophila erecta (Fruit fly)Imported
Taxonomic identifieri7220 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000008711 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0106350. Dere\GG14088.

Structurei

3D structure databases

ProteinModelPortaliB3NGD1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldose epimerase family.UniRule annotation

Phylogenomic databases

KOiK01785.
OrthoDBiEOG7V7666.
PhylomeDBiB3NGD1.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR018052. Ald1_epimerase_CS.
IPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.
PROSITEiPS00545. ALDOSE_1_EPIMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3NGD1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVNVTEEVFA NGAVNPFTKS KDTIKRFTLS NGAGMSVQLI TRGATITSIK
60 70 80 90 100
TPDASGQIDD VTLGFDDLAG YQSDRNPYFG ATIGRVCNRI ANGSFYLDGK
110 120 130 140 150
LVEVSKNRDN KFQLHGGFVG FDKAHWEVVE VCRDGVTLSH TNPDGHEGYP
160 170 180 190 200
GNVTATASFT LSEDNCLHVQ MSAVTDKTTP VNLTNHSYFN LAGHKSGANG
210 220 230 240 250
LYEHNIEINA YGITETDQSS IPTGGITPVE GTGFDLRVSS NLGERLKALQ
260 270 280 290 300
PARGYDDNFC VTFTPPQPMV KVARATHPPS GRWLEVVSNQ PGVQFYTSNF
310 320 330 340 350
MPDVERGETP IPGKDGAAYA KHGAFCLETQ KFPDSVNHSN FPSTILRPGD
360
SYRHEVIYKF GVSH
Length:364
Mass (Da):39,576
Last modified:September 2, 2008 - v1
Checksum:iAEF8205EE6A1B6D0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH954178 Genomic DNA. Translation: EDV51097.1.
RefSeqiXP_001972071.1. XM_001972035.1.

Genome annotation databases

EnsemblMetazoaiFBtr0134142; FBpp0132634; FBgn0106350.
GeneIDi6545282.
KEGGider:Dere_GG14088.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH954178 Genomic DNA. Translation: EDV51097.1.
RefSeqiXP_001972071.1. XM_001972035.1.

3D structure databases

ProteinModelPortaliB3NGD1.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0134142; FBpp0132634; FBgn0106350.
GeneIDi6545282.
KEGGider:Dere_GG14088.

Organism-specific databases

FlyBaseiFBgn0106350. Dere\GG14088.

Phylogenomic databases

KOiK01785.
OrthoDBiEOG7V7666.
PhylomeDBiB3NGD1.

Enzyme and pathway databases

UniPathwayiUPA00242.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR018052. Ald1_epimerase_CS.
IPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.
PROSITEiPS00545. ALDOSE_1_EPIMERASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 14021-0224.01Imported.

Entry informationi

Entry nameiB3NGD1_DROER
AccessioniPrimary (citable) accession number: B3NGD1
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: February 4, 2015
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.