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Protein

Hexokinase

Gene

Dana\GF20735

Organism
Drosophila ananassae (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. kinase activity Source: UniProtKB-KW
  3. phosphotransferase activity, alcohol group as acceptor Source: InterPro

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
Name:Dana\GF20735Imported
ORF Names:Dana_GF20735Imported, GF20735Imported
OrganismiDrosophila ananassae (Fruit fly)Imported
Taxonomic identifieri7217 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000007801 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0097741. Dana\GF20735.

Interactioni

Protein-protein interaction databases

STRINGi7217.FBpp0123927.

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation
Contains 1 hexokinase type-1 domain.UniRule annotation
Contains 1 hexokinase type-2 domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG5026.
InParanoidiB3N1M6.
KOiK00844.
OrthoDBiEOG7TBC24.
PhylomeDBiB3N1M6.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.

Sequencei

Sequence statusi: Complete.

B3N1M6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAAKDESFV PERDFPEVHK MCKLFVPSED DLEKIMQLMD REITMGLTRE
60 70 80 90 100
GHERSTVPCK LSYVTDLPNG RERGQFLALE MMPTNCRIML VKFSSERDVY
110 120 130 140 150
TSSKCVIMPH TVAAGKGTEV FNFLASNIAT FVKEKKVEKE NMPLGIAFAF
160 170 180 190 200
TLNKTALDAG TLVSWTKEFG ATGAIGKDVV QLLREALAKF PEISVDVMGI
210 220 230 240 250
INVAAGSLLA LCWAQPDTRM GLIMGSIANS CYVEKIEKCD LYQGDPFKKI
260 270 280 290 300
MIINSDWAHF GDGGQLDFIR NEFDRQLDAE SITPGLRIYE KFSGALCLAE
310 320 330 340 350
LVRIVVLRLM KMGVIFEDGR RDYIGIQWKM DMVSLIEIES DPPGVYTRAQ
360 370 380 390 400
EVMDKFKIRH CSEKDLAALK YICATISNRA AMVVASGVAA LINRMKMPQI
410 420 430 440 450
SIAVDGGIYR LHPTYATVLN KYTKLLVDPH YKFEFVITQD SCGVGAAIMA
460
GMAHAQKYKT DAKLFEMDY
Length:469
Mass (Da):52,433
Last modified:September 2, 2008 - v1
Checksum:i82D727E66A3EF5D9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH902661 Genomic DNA. Translation: EDV33995.1.
RefSeqiXP_001967461.1. XM_001967425.1.

Genome annotation databases

EnsemblMetazoaiFBtr0125435; FBpp0123927; FBgn0097741.
GeneIDi6503428.
KEGGidan:Dana_GF20735.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH902661 Genomic DNA. Translation: EDV33995.1.
RefSeqiXP_001967461.1. XM_001967425.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7217.FBpp0123927.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0125435; FBpp0123927; FBgn0097741.
GeneIDi6503428.
KEGGidan:Dana_GF20735.

Organism-specific databases

FlyBaseiFBgn0097741. Dana\GF20735.

Phylogenomic databases

eggNOGiCOG5026.
InParanoidiB3N1M6.
KOiK00844.
OrthoDBiEOG7TBC24.
PhylomeDBiB3N1M6.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
ProtoNetiSearch...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 14024-0371.13Imported.

Entry informationi

Entry nameiB3N1M6_DROAN
AccessioniPrimary (citable) accession number: B3N1M6
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: March 4, 2015
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.