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Protein

Hexokinase

Gene

Dana\GF22320

Organism
Drosophila ananassae (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
Name:Dana\GF22320Imported
ORF Names:Dana_GF22320Imported, GF22320Imported
OrganismiDrosophila ananassae (Fruit fly)Imported
Taxonomic identifieri7217 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000007801 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0099318. Dana\GF22320.

Interactioni

Protein-protein interaction databases

STRINGi7217.FBpp0125512.

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG5026.
InParanoidiB3MW58.
KOiK00844.
OrthoDBiEOG7S21X5.
PhylomeDBiB3MW58.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 1 hit.
PS51748. HEXOKINASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3MW58-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDRELNGAMR SVSINSNGTA QLNGHSRDET DRVGGVPGGV VTATAAAAAA
60 70 80 90 100
SQTTTKCSST ANANATAATN AAIALEANLF AAASASEKKK MVHELCQQLL
110 120 130 140 150
LTDEQVQELC YRILHELRRG LAKDTHPKAN VKCFVTYVQD LPNGNERGKF
160 170 180 190 200
LALDLGGTNF RVLLIHLQEN NDFQMESRIY AIPQHIMIGS GTQLFDHIAE
210 220 230 240 250
CLSNFMAEHN VYQERLPLGF TFSFPLRQLG LTKGLLETWT KGFNCAGVVN
260 270 280 290 300
EDVVQLLKDA IARRGDVQID VCAILNDTTG TLMSCAWKNH NCKIGLIVGT
310 320 330 340 350
GANACYMERV EEAELFDVEA DNKKPHVLIN TEWGAFGDNG ALDFVRTEFD
360 370 380 390 400
RDIDVHSINP GKQTFEKMIS GMYMGELVRL VLVKMTHAGI LFNGQDSEVL
410 420 430 440 450
NTRGLFFTKY VSEIEADEPG TFTNCRLVLE ELGLTNATDG DCANVRYICE
460 470 480 490 500
CVSKRAAHLV SAGIATLINK MDEPHVTVGV DGSVYRFHPK FHNLMVEKIS
510 520 530
KLIKPGITFD LMLSEDGSGR GAALVAAVAC REDMLSPKK
Length:539
Mass (Da):58,927
Last modified:September 2, 2008 - v1
Checksum:iB8ED832F1C9DA1D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH902625 Genomic DNA. Translation: EDV35203.1.
RefSeqiXP_001965688.1. XM_001965652.1.

Genome annotation databases

EnsemblMetazoaiFBtr0127020; FBpp0125512; FBgn0099318.
GeneIDi6504984.
KEGGidan:Dana_GF22320.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH902625 Genomic DNA. Translation: EDV35203.1.
RefSeqiXP_001965688.1. XM_001965652.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7217.FBpp0125512.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0127020; FBpp0125512; FBgn0099318.
GeneIDi6504984.
KEGGidan:Dana_GF22320.

Organism-specific databases

FlyBaseiFBgn0099318. Dana\GF22320.

Phylogenomic databases

eggNOGiCOG5026.
InParanoidiB3MW58.
KOiK00844.
OrthoDBiEOG7S21X5.
PhylomeDBiB3MW58.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 1 hit.
PS51748. HEXOKINASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 14024-0371.13Imported.

Entry informationi

Entry nameiB3MW58_DROAN
AccessioniPrimary (citable) accession number: B3MW58
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: June 24, 2015
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.