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B3MTV1

- B3MTV1_DROAN

UniProt

B3MTV1 - B3MTV1_DROAN

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Protein
Submitted name:

GF23177

Gene

Dana\GF23177

Organism
Drosophila ananassae (Fruit fly)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

GO - Molecular functioni

  1. histone methyltransferase activity (H3-K4 specific) Source: InterPro
  2. sequence-specific DNA binding Source: InterPro
  3. sequence-specific DNA binding transcription factor activity Source: InterPro
  4. zinc ion binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotation, Transferase

Keywords - Ligandi

Metal-binding, S-adenosyl-L-methionineSAAS annotation, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
GF23177Imported
Gene namesi
Name:Dana\GF23177Imported
ORF Names:Dana_GF23177Imported, GF23177Imported
OrganismiDrosophila ananassae (Fruit fly)Imported
Taxonomic identifieri7217 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000007801: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0100171. Dana\GF23177.

Subcellular locationi

GO - Cellular componenti

  1. histone methyltransferase complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi7217.FBpp0126369.

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains 2 post-SET domains.UniRule annotation
Contains SET domain.SAAS annotation
Contains post-SET domain.SAAS annotation

Keywords - Domaini

Zinc-fingerSAAS annotation

Phylogenomic databases

eggNOGiCOG2940.
InParanoidiB3MTV1.
KOiK09186.
OrthoDBiEOG75XGJZ.
PhylomeDBiB3MTV1.

Family and domain databases

Gene3Di3.30.40.10. 3 hits.
InterProiIPR003889. FYrich_C.
IPR003888. FYrich_N.
IPR016569. MeTrfase_trithorax.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR011011. Znf_FYVE_PHD.
IPR001628. Znf_hrmn_rcpt.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF05965. FYRC. 1 hit.
PF05964. FYRN. 1 hit.
PF00628. PHD. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
PIRSFiPIRSF010354. Methyltransferase_trithorax. 1 hit.
SMARTiSM00542. FYRC. 1 hit.
SM00541. FYRN. 1 hit.
SM00249. PHD. 4 hits.
SM00508. PostSET. 2 hits.
SM00184. RING. 4 hits.
SM00317. SET. 1 hit.
[Graphical view]
SUPFAMiSSF57903. SSF57903. 2 hits.
PROSITEiPS51543. FYRC. 1 hit.
PS51542. FYRN. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
PS50016. ZF_PHD_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3MTV1-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MGRSKFPGKP SKSINRKRIS VLQLEDDQPQ QQPETQPDSQ PDTQQQQQQQ
60 70 80 90 100
TSSGSGAGSL TAREKGNNCD KDEDDNAPGG ASSTGGNNAS SSSASSSEST
110 120 130 140 150
GNGNSSASGS SSGSTNGGSV NGASSHKNAA NSDKEHQGEA KDGDKGRTKT
160 170 180 190 200
APLGGAASLG GKSSRTSSGS SASGAAFEKC AGGKGAKPPT GTASGKSCGS
210 220 230 240 250
GSVISIEISS GKQSEAASPR ALAGLSPGAS SASSSGLASP GGSSSGSFAL
260 270 280 290 300
SAALLRARKG SNKKFKNLNL ARAEVMLPST SKLKMQQQQE LNGPGAAGSG
310 320 330 340 350
SSSAPSPSSA ETAGMGLANP FAGEAGEDAA LKRRLADMPH EVASETASTS
360 370 380 390 400
SGSAGNDAAA GATTTAGAGP SGSAAGCSPK PGQAAAATGS GPGPAKQKKT
410 420 430 440 450
VTFRNVLETS DDKSVVKRFY NPDNRIPLVS IMKKDSLNRP LNYSRGGECI
460 470 480 490 500
VRPSILSKIL NKSSNIDKLN SLKFRSAPSS SGKSSESPNV FGLSRAFGAP
510 520 530 540 550
MDEDEEESGG VTFRRNDSPP GQKIDDDDDD MDEDEDEEEG NLDEEDNEQE
560 570 580 590 600
DIDEGVSEKS AETDRNGRES EERDSEEKQL VMDSHFVLPK RSTRSSRIIK
610 620 630 640 650
PNKRLIEDGA ISKKSAPSSS DSKSKSLFGA PAPSTSSTSA AGFSSFGSLK
660 670 680 690 700
LNSNTSGSGS GSGSGSGSGS FVLRQPRLRF QTDSKPVPFG SAAATKSSCP
710 720 730 740 750
TSPSAIQTPA SSLAMTSFGT LATSSSSPNP NPAAGSAGSS TCSVCSTSVS
760 770 780 790 800
SKEVAQPRKY GVVACDVCRK FMSKMTKKSI SANSSSPNAA GSSGGQQHLQ
810 820 830 840 850
CKGAEGSACS ILTAKSQLKN FKKLYKERCT ACWLKKCVNS FQLPAAHRSR
860 870 880 890 900
LSAILPAAMR VDVSSREDKS TELLSPTGSI RFTAPSALSS SSVAASTSVK
910 920 930 940 950
WKSSGDSSSS ALASIKSNPL AENNVTFGST PLLRPAILEK PLFLKISNAA
960 970 980 990 1000
DQKLGANEVG CPSPSRKAKQ DEEKEKEKEK EKEKAKDQDV GDKLLSPTLS
1010 1020 1030 1040 1050
ASKKPPSAEN PIPEAQKEEA QSSTTTMQAG TLNGTSQATN QSEANGDSNP
1060 1070 1080 1090 1100
NSNANATSSG ETLKRQRIDL KGPRVKHVCR SASIVLGQPL ATFGEDQEAE
1110 1120 1130 1140 1150
EEAEVQKEAV VPVPSESSAQ KPEPVVTDEN DNCASCKTHP SDGSNASQAS
1160 1170 1180 1190 1200
GSNQGEARKV APAGKENVTV AKAEPAAPSV PAKVATRNAT VASNMNVVAT
1210 1220 1230 1240 1250
KKQRNGDITS SSVTQTSNLS QGRRTKEQRQ QRTLISIDFW ENYDPAEVCQ
1260 1270 1280 1290 1300
TGFGLIVTET VAQRALCFLC GSTGLDPLIF CACCCEPYHQ YCVQDEYNLK
1310 1320 1330 1340 1350
HSSFEETTLM GSLLETSVTA VGSSSSLNQL TQRLNWLCPR CTVCYTCNMS
1360 1370 1380 1390 1400
SGSKVKCQKC QKNYHSTCLG TSKRLLGADR PLICVNCLKC KSCSTTKVSK
1410 1420 1430 1440 1450
FVGNLPMCTN CFKLRKKGNF CPICQKCYDD NDFDLKMMEC GDCRQWVHSK
1460 1470 1480 1490 1500
CEGLSDEQYN LLSTLPESIE FICKKCARRN ESSKMKAEEW RQAVMEEFKV
1510 1520 1530 1540 1550
SLYSVLKLLS KSRQACALLK LSPRKKLRCT CGAAGKLQPK ALQFSSGSDN
1560 1570 1580 1590 1600
GLGSDGESQN SDDVYEFKEQ QQRNMNQNKS RVGKSLSCSC QQPISQPQSF
1610 1620 1630 1640 1650
SLVDIKQKIA NNSYVSLAEF NYDMSRVIQQ SNCDELDIAY KELLSEQFPW
1660 1670 1680 1690 1700
FQNETKACTD ALEEDMFESC AGGNYEDLPD GAGGSSVYND HSTSQGESRS
1710 1720 1730 1740 1750
GVLDIPIEEV DDLGSCGIKM RLDSRVCLFC RKSGEGLSGE EARLLYCGHD
1760 1770 1780 1790 1800
CWVHTNCAMW SAEVFEEIDG SLQNVHSAVA RGRMIKCTVC GNRGATVGCN
1810 1820 1830 1840 1850
VRSCGEHYHY PCARSIECAF LTDKSMYCPT HAKNGNALKA NGSPSVTYES
1860 1870 1880 1890 1900
NFEVSRPVYV ELDRKRKKLI EPVRVQFHIG SLEVRQLGTI VPRFSDSYEA
1910 1920 1930 1940 1950
VVPINFLCSR LYWSSKEPWK IVEYTVRTTI QNSSSSTLTA LDVGRNYTVD
1960 1970 1980 1990 2000
HSNPNGKEVQ LGLAQIARWH STLARSDLLE SNGTDWNGDF ANQNSCVPPD
2010 2020 2030 2040 2050
ENTEEEPQQQ ADLLPPEIKD AIFEDLPHEI LDGISMLDIF MYDDLADKSD
2060 2070 2080 2090 2100
LFAISEQSKD GTQAMTSHQA QSQQGQQAGG GSVSICDEDT RNSNTSLGNA
2110 2120 2130 2140 2150
WPASNPVEDA MLSAARNSSQ VQMLKTLAWP KLDGNCAMAT AIKRRKLSKN
2160 2170 2180 2190 2200
LAEGVILTLS SQQRSKKEMA TVAGVSRRQS ISETSTEASS SSSVRSKSFT
2210 2220 2230 2240 2250
WSAAKRYFEK SEGREEAAKM RIMQMDGVDD SITEYRIIAD GNLSTAQFTG
2260 2270 2280 2290 2300
QLKCERCQCT YRNYDAFQRH LPGCEPAMST NDTESEVNAT GTTTNATHLS
2310 2320 2330 2340 2350
AESLNELQKQ LLANAGGLNY LQTAAAATTF PQVQSLGSLG QFGLQGLQPL
2360 2370 2380 2390 2400
QLQPQSLGNG FFLSQPNPAP SQSNGTEELQ IYANSLQSLA ANLGGGFTLA
2410 2420 2430 2440 2450
QPTVTAAPQP QLIAVSTNPD GTQQFIQIPQ TTAPAATYQT LQATNTDKKI
2460 2470 2480 2490 2500
VLPLSTAGKP LKTVATKAAQ QAAAKQKQLK SGHQVKPIQA KLQPHPQQQA
2510 2520 2530 2540 2550
TQVQQAQPIT VMGQNLLQPQ LLFQSSAQAQ TPQLILPQTQ PQNIISFVTG
2560 2570 2580 2590 2600
DGSQGQPLQY ISIPTGGEYK PQPQPTATPT FLTTAAPGAG ATFLQTDASG
2610 2620 2630 2640 2650
NLMLTTAPTN SGLQMLTAAP LQSQPQVIGT LIQPQTLQLS GATDGSQPGA
2660 2670 2680 2690 2700
SQQSLILGGT SGGGTTGLEF ATTTPQVILA TQPMYYGLET IVQNTVMSSQ
2710 2720 2730 2740 2750
QFVSTAMPGV LSQNASFSAT TTQVFQASKI EPIVDLPAGY VVLNNPTDGT
2760 2770 2780 2790 2800
GAGTFLNAAS VLQQQQSQDD LLQNANFQFQ AVPSSSSSAT LDYSAPLVVT
2810 2820 2830 2840 2850
AKIPPVTQMK RANSNAGKAA GVSGVSKVPP QVVNKVLPTS IAAQQSQVQL
2860 2870 2880 2890 2900
KNTTSGNLKH TVKGKAVSQT GTNCGAPPSI ASKPLQKKTN LIRPIHKLEV
2910 2920 2930 2940 2950
KPKVMKPAPK VHVQNHAILQ QQQQQQTVPQ QQPAAPKITI TQQRIPVQTQ
2960 2970 2980 2990 3000
QQQPQPTQLL QISQPLHQQP QPVHVPQQQL QVQVQPSMPI ITIAEAPALQ
3010 3020 3030 3040 3050
TQFVIDQQEL VNQQEMVNRA QHFAGSSTSN SLPTNVVNPL QQQAPPTTNI
3060 3070 3080 3090 3100
STTRPTNRVL PMQQRQDPNP PTIESPVMPS PTPPKPLEQQ VIQQITSASA
3110 3120 3130 3140 3150
PKCYMPKTVS PIYEAELKTV TGLDSIVPSN VDCEIMEQPV TESIYTEGLY
3160 3170 3180 3190 3200
EKHSPSDAKT EQLIIQQQQR EQLTQHLANN SFLLEKHTFE VDAMDTDSYR
3210 3220 3230 3240 3250
DDDLEDEDDE EDDFSLKMAA SVGNDHEMSD TEEPAVKDKI SKILDNLTND
3260 3270 3280 3290 3300
DCADSIATAT TAEVEASAAG YQQMVEDVLA TTAAASSAPT EEFEGTLETA
3310 3320 3330 3340 3350
AVEAAASYIN EMAEAHVLEL KQLENGVELE LTRRKGEPQK QESVAKQQVK
3360 3370 3380 3390 3400
VPTAAAPEPP PPIREPKKIS GPHLLYEIQS EDGFTYKSSS ISEIWEKVFE
3410 3420 3430 3440 3450
AVQVARRAHG LTPLPEGPLA DMGGIQMIGL KTNALKYLIE QLPGVEKCSK
3460 3470 3480 3490 3500
YTPKYHKRNG NVSTAANAGH GGSTGGGNAS LASNGDPQAL LDYGSDQDEL
3510 3520 3530 3540 3550
QENAFECARC EPYSSRSDYD MFSWLASRHR KQPIQVFVQP SDSELVPRRG
3560 3570 3580 3590 3600
TGSNLPMAMK YRTLKETYKD YVGVFRSHIH GRGLYCTKDI EAGEMVIEYA
3610 3620 3630 3640 3650
GELIRSTLTD KRERYYDSRG IGCYMFKIDD NLVVDATMRG NAARFINHSC
3660 3670 3680 3690 3700
EPNCYSKVVD ILGHKHIIIF ALRRIVQGEE LTYDYKFPFE EEKIPCSCGS

KRCRKYLN
Length:3,708
Mass (Da):397,280
Last modified:September 2, 2008 - v1
Checksum:i299F76CCBF9F853E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH902623 Genomic DNA. Translation: EDV30232.1.
RefSeqiXP_001964436.1. XM_001964400.1.

Genome annotation databases

EnsemblMetazoaiFBtr0127877; FBpp0126369; FBgn0100171.
GeneIDi6505823.
KEGGidan:Dana_GF23177.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH902623 Genomic DNA. Translation: EDV30232.1 .
RefSeqi XP_001964436.1. XM_001964400.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 7217.FBpp0126369.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0127877 ; FBpp0126369 ; FBgn0100171 .
GeneIDi 6505823.
KEGGi dan:Dana_GF23177.

Organism-specific databases

FlyBasei FBgn0100171. Dana\GF23177.

Phylogenomic databases

eggNOGi COG2940.
InParanoidi B3MTV1.
KOi K09186.
OrthoDBi EOG75XGJZ.
PhylomeDBi B3MTV1.

Family and domain databases

Gene3Di 3.30.40.10. 3 hits.
InterProi IPR003889. FYrich_C.
IPR003888. FYrich_N.
IPR016569. MeTrfase_trithorax.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR011011. Znf_FYVE_PHD.
IPR001628. Znf_hrmn_rcpt.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view ]
Pfami PF05965. FYRC. 1 hit.
PF05964. FYRN. 1 hit.
PF00628. PHD. 1 hit.
PF00856. SET. 1 hit.
[Graphical view ]
PIRSFi PIRSF010354. Methyltransferase_trithorax. 1 hit.
SMARTi SM00542. FYRC. 1 hit.
SM00541. FYRN. 1 hit.
SM00249. PHD. 4 hits.
SM00508. PostSET. 2 hits.
SM00184. RING. 4 hits.
SM00317. SET. 1 hit.
[Graphical view ]
SUPFAMi SSF57903. SSF57903. 2 hits.
PROSITEi PS51543. FYRC. 1 hit.
PS51542. FYRN. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
PS50016. ZF_PHD_2. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tucson 14024-0371.13Imported.

Entry informationi

Entry nameiB3MTV1_DROAN
AccessioniPrimary (citable) accession number: B3MTV1
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: November 26, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3